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CBG and CBGa Cannabinoids Professor DeBacco Research Article Russo, E. B. (2011). Taming THC: potential cannabis synergy and phytocannabinoid‐terpenoid entourage effects. British journal of pharmacology, 163(7), 1344-1364. https://www.researchgate.net/publication/51485891_Taming_THC_Potential_cannabis_synergy_and_phytocannabinoid-terpenoid_entourage_effects CBGA Pathway CBGA is produced from GPP and OA by the synthase “Aromatic Prenyltransferase” or AP. This biochemistry takes place in the plastid, which is also where the MEP pathway produces GPP and terpenes. GPP is a shared substrate for both cannabinoids and terpenes. After CBGA is synthesized, it is transported out of the plastid in a “hyaline” glob (Mahlberg), into the apoplast (Gulck). This is where the conversion of CBGA to subsequent cannabinoids takes place. If CBGA is not converted into a subsequent cannabinoid, it will accumulate in the trichome. Heat may cause it to convert to its neutral, active form, CBG. Interaction with Cannabinoid Receptors CBGA and CBG have been shown to interact with cannabinoid receptors that bind CBD and THC, modulating their effect. Anecdotal Reports Many anecdotal reports have shown that CBG has similar effects to CBD. Medical studies have shown that CBG is a “potent adrenoceptor agonist,” (Cascio et al 2010) and other studies have shown that CBG has antibiotic properties (Appendino et al 2008). It is worth noting that all of the general side-chain cannabinoids have been shown to exhibit potent antimicrobial properties. Cannabinoid Biosynthesis CBGA is the cannabinoid precursor The biosynthesis pathway leads through (or can be restricted by) CBGA Link to Lecture Slides: https://drive.google.com/file/d/1txUxTJ9Ho6Z3R4jH5jOYUHjQuzwO2GSm/view?usp=sharing *Due to the description character limit the full work cited for "CBG and CBGa Cannabinoids" can be viewed at... https://drive.google.com/file/d/1wi6esQPT0U7bIZdU5zoJqSstbUTmMCwe/view?usp=sharing

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Dr. Natalie Klag of @OSUWexMed focuses on the distinction between THC and CBD and their potential benefits and risks for professional athletes. Dr. Klag and Host Dan Hauser elaborate on the different components of cannabis and how CBD could benefit athletes, especially in areas like pain management and concussion recovery. #professionalsports #marijuana #cannabis #prosports #sports #marijuanaindustry #addictionrecovery #cannabismedicinal #painmanagement #mentalhealth #sportspsychology #sportsnews #sportsmentalhealth #addictionhelp #podcast #boardcertified Produced by @ChrisCarberg and @MichaelMoesch-kd4ly Copyright, AddictionHelp.com, 2023. All rights reserved.

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Be careful where you put your edibles. Dogs don’t know they not food.

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Marijuana gummies have become increasingly popular in recent years as an alternative way to consume cannabis. These gummies offer a convenient and discreet method of enjoying the effects of marijuana, without the need to smoke or vape. They come in a variety of flavors and strengths, catering to different preferences and tolerance levels.

Flavors

One of the most appealing aspects of marijuana gummies is the wide range of flavors available. From fruity options like strawberry, watermelon, and cherry, to more exotic choices like mango, pineapple, and passion fruit, there is a flavor to suit every palate. Some brands even offer unique combinations such as blue raspberry lemonade or green apple caramel.

Each flavor can enhance the overall experience of consuming marijuana gummies, providing a burst of taste that complements the effects of the cannabis. Whether you prefer sweet, sour, or tangy flavors, there is bound to be a gummy option that you will enjoy.

Additionally, some manufacturers infuse their gummies with natural fruit juices and organic ingredients, adding an extra layer of quality and flavor to the product. These premium options may come at a higher price point, but many consumers find them to be worth the investment for the enhanced taste experience.

Effects

When it comes to the effects of marijuana gummies, there are a few key factors to consider. The potency of the gummies will depend on the dosage of THC and CBD, the two main active compounds in cannabis. Higher THC levels typically result in a stronger psychoactive effect, while CBD is known for its calming and therapeutic properties.

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Consumers should be mindful of their tolerance levels and start with a low dosage to assess their individual response to the gummies. It is recommended to wait at least 1-2 hours after consuming a gummy before deciding to take more, as the effects may take some time to kick in fully.

In general, marijuana gummies offer a longer-lasting high compared to smoking or vaping cannabis, as the edible form is metabolized differently in the body. This slower onset and prolonged duration can be beneficial for those looking for a more sustained experience, whether for recreational or medicinal purposes.

Tips for Enjoying Marijuana Gummies

To maximize your enjoyment of marijuana gummies, consider the following tips:

1. Start with a low dosage and wait patiently for the effects to kick in before taking more.

2. Stay hydrated and have some snacks on hand to help alleviate any potential cottonmouth or munchies.

3. Experiment with different flavors and brands to find your favorites and discover new taste sensations.

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