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Este vídeo explica o funcionamento do sistema endocanabinóide, sua importância e como o canabidiol ajuda a mantê-lo equilibrado. Quer saber mais sobre o tratamento com Canabidiol? Quais os benefícios do cânhamo medicinal? Acesse: https://goo.gl/QZoM2a EndoPure Life Sciences Mais Natureza, Mais Vida #tratamento #canabidiol #autismo #cbd

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Cannabis is rapidly becoming one of the most consumed drugs in Canada. Many report using the drug as a coping mechanism for stress and anxiety. How exactly do our stress responses change in the presence of cannabis? Does cannabis actually relieve stress? This video considers the stress relieving effects of cannabis as it interacts with our body’s stress reaction system: the hypothalamic pituitary adrenal axis (HPA-axis). Followed by the potential of cannabis for treating chronic and acute stress related disorders. As research continues on the full uses of cannabis, this video serves as an overview of the research published thus far. If you are using cannabis to cope with stress, please do so safely by monitoring your usage, and reaching out to a registered healthcare professional for more guidance on coping with stress. This video was made by McMaster students Armaan Sekhon, Kriti Manuja, Krishna Patel & Sharleen Maduranayagam in collaboration with the McMaster Demystifying Medicine Program. Copyright McMaster University 2021 References: Canadian Centre on Substance Use and Addiction. (n.d.). Cannabis (Canadian Drug Summary) [Topic Summary]. Retrieved October 9, 2020, from https://www.ccsa.ca/cannabis-canadian-drug-summary Childs, E., Lutz, J. A., & de Wit, H. (2017). Dose-related effects of delta-9-THC on emotional responses to acute psychosocial stress. Drug and Alcohol Dependence, 177, 136–144. https://doi.org/10.1016/j.drugalcdep.2017.03.030 Cuttler, C., Spradlin, A., Nusbaum, A. T., Whitney, P., Hinson, J. M., & McLaughlin, R. J. (2017). Blunted stress reactivity in chronic cannabis users. Psychopharmacology, 234(15), 2299–2309. https://doi.org/10.1007/s00213-017-4648-z Gruber, S. A., Rogowska, J., & Yurgelun-Todd, D. A. (2009). Altered affective response in marijuana smokers: An FMRI study. Drug and Alcohol Dependence, 105(1–2), 139–153. https://doi.org/10.1016/j.drugalcdep.2009.06.019 Hyman, S. M., & Sinha, R. (2009). Stress-Related Factors in Cannabis Use and Misuse: Implications for Prevention and Treatment. Journal of Substance Abuse Treatment, 36(4), 400–413. https://doi.org/10.1016/j.jsat.2008.08.005 Micale, V., & Drago, F. (2018). Endocannabinoid system, stress and HPA axis. European Journal of Pharmacology, 834, 230–239. https://doi.org/10.1016/j.ejphar.2018.07.039 Orsolini, L., Chiappini, S., Volpe, U., De Berardis, D., Latini, R., Papanti, G. D., & Corkery, J. M. (2019). Use of Medicinal Cannabis and Synthetic Cannabinoids in Post-Traumatic Stress Disorder (PTSD): A Systematic Review. Medicina, 55(9). https://doi.org/10.3390/medicina55090525 Somaini, L., Manfredini, M., Amore, M., Zaimovic, A., Raggi, M. A., Leonardi, C., Gerra, M. L., Donnini, C., & Gerra, G. (2012). Psychobiological responses to unpleasant emotions in cannabis users. European Archives of Psychiatry and Clinical Neuroscience, 262(1), 47–57. https://doi.org/10.1007/s00406-011-0223-5 Turna, J., Patterson, B., & Van Ameringen, M. (2017). Is cannabis treatment for anxiety, mood, and related disorders ready for prime time? Depression and Anxiety, 34(11), 1006–1017. https://doi.org/10.1002/da.22664

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What is Delta-10 THC with Dr. Matt Moore What is Delta-10 THC? The Dime has its first returning guest, Dr. Matt Moore, principal scientist at Benuvia Manufacturing to discuss Delta-10 THC. Before listening to today’s episode, check out our prior session with Dr. Moore where we discussed Delta-8 THC (link: https://anchor.fm/thedime/episodes/Delta-8-THC-Deep-Dive-featuring-Dr--Matt-Moore-epgkvn) or our intro to Delta-8 episode (link: https://anchor.fm/thedime/episodes/Delta-8-THC-emd2s8) Chapters: 00:00:00 - Introduction: Sponsored by 8th Revolution 00:02:43 - The Science Behind Delta-8, Delta-9, and Other Cannabinoids 00:05:16 - Understanding Delta-10 THC and Its Psychoactive Potential 00:07:53 - Understanding the Shape and Psychoactive Characteristics of Cannabinoids, Specifically Delta-10 00:10:27 - Innovating Science and Making D10 from CBD 00:12:54 - The Challenges of Synthesizing Delta-10 THC 00:15:08 - The Cat and Mouse Game of THC and CBD Regulation 00:17:34 - Regulation of THC analogs and the FDA's dilemma 00:20:00 - The Potential of Delta 10 THC 00:22:32 - Speculative Claims about Cannabinoids and Increased Focus with Reduced Anxiety 00:24:58 - Vetted Claims and Misleading Marketing of Cannabinoids 00:27:19 - The Role of Terpenes and the Entourage Effect in Cannabis 00:29:44 - Attenuation of Cannabinoids and the Future of Cannabis Science 00:32:12 - The future regulation of the cannabinoid industry 00:34:40 - The Dangers of Buying Products Online and the Complexity of the Cannabis Industry 00:37:04 - The Difficulty of Organic Chemistry and the Grey Area of Marketing New Products 00:39:34 - The Importance of Purity Levels in Cannabinoids 00:42:00 - The Future of Legalization and Designer Cannabinoids 00:44:34 - Predictions for Future Cannabinoids 00:47:16 - The Potential Future of Synthetic Cannabinoids and the Controversial THCO Molecule 00:49:46 - The Risks of Mixing Alcohol and Smoking Lounges, Technical Issues Apologized For Featured in today’s episode: · Delta-10 THC · Tetrahydrocannabinol clinical research and analysis · Lawmakers lack knowledge about cannabis · What should be on the radar of people in the Cannabinoid space? Become a supporter of The Dime Podcast: https://anchor.fm/thedime/support Benuvia Manufacturing is a leading developer and manufacturer of high-purity, pharmaceutical cannabinoid ingredients and products.