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This trial is testing cannabidiol (CBD) to see if it's an effective treatment for symptoms associated with autism spectrum disorder (ASD), in children and adolescents. They are using a 98% pure CBD oral solution, given at a dose of 9 mg/kg/day. They will be testing up to 15 additional participants who also have a diagnosis of attention deficit/hyperactivity disorder (ADHD). This is a Phase 2 trial recruiting patients with Autism Spectrum Disorder. 00:00:28 How long is the trial? 00:00:38 Who can enroll? 00:01:07 Where is the study located? Discover more information about the trial and apply through Power here: http://bit.ly/3gKq6bK #autismspectrumdisorders #clinicaltrials #autismspectrumdisordersresearch #adhdclinicaltrials

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Recently, late actor Irrfan khan’s wife made an appeal to legalize CBD oil in India. Her appeal witnessed some criticism. The recent controversy about the use of drugs in Bollywood has stigmatized the usage of CBD. CBD oil is basically an extract from the cannabis plant. In this DNS we will know - What is CBD oil? What are its effects? Is its use and consumption legal in India? Voice and Script: Shiba Graphics: Pankaj Jain Editor: Shailesh Kumar

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In this video, I'll explain marijuana metabolism. I'll show how our body processes and excretes marijuana and its metabolites. Possessing this knowledge is extremely important in your understanding of how to detox from marijuana. DELTA-9-THC or THC is the primary psychoactive ingredient of cannabis. When cannabis is smoked or vaporized, THC enters the bloodstream via absorption through the lungs. According to a research study, we inhale only about 50% of the THC from the joint. Approximately 30% of the THC is destroyed by heat. Other THC is lost through sidestream and incomplete absorption in the lungs. Therefore, only a part of inhaled THC reaches body circulation due to what is called the first-pass metabolism. Because of the first-pass metabolism only 25-30% of smoked THC is absorbed into the blood. Studies have shown that heavy users receive ~25% of the THC available for absorbtion while occasional users get ~12%, the reason being because heavy users smoke more efficiently. When ingested as edibles, THC enters the bloodstream through the walls of the stomach and intestines. Tests show that 90-95% of the THC then permeates the blood after ingestion. THC and some of its metabolites are fat-soluble. This means that they can dissolve in fats or oils. THC rapidly penetrates highly vascularized tissues such as the lungs, liver, heart, and body fat. About 70% of the THC is taken up by tissues, mostly by body fat. The THC is then slowly released back into the blood. Through this process, THC is continuously moving from the fat tissues into the blood and back again. Once in the blood, THC infiltrates the liver and undergoes 2 phases of metabolism. The CYP2C9 enzyme converts THC to 11-OH-THC in the first phase, after which CYP2C19 and CYP3A4 enzymes convert 11-OH-THC to 11-COOH-THC. THC metabolites are prepared for excretion in the second phase. UGT enzymes add a glucuronide molecule to metabolites through a process known as glucuronidation. 11-COOH-THC is metabolized mainly by the UGT1A3 enzyme and forms THC-COO-Gluc. 11-OH-THC is metabolized mainly by UGT1A9 and UGT1A10 enzymes and forms THC-O-Gluc. The resulting metabolites are soluble in water. Afterwards, they are dissolved in the bile and water and excreted with the urine and feces. In the intestines, bacterial enzymes 'remove' glucuronide from most of the THC metabolites. These metabolites are then reabsorbed back into the blood, where they can begin the entire cycle over again. This process is called enterohepatic circulation. One unfortunate aspect of this process is that only about 20% of THC metabolites are excreted with the urine, while 65% are excreted with the feces. Therefore, most of the THC metabolites will enter the enterohepatic recirculation and return into your blood. This is why detoxification from marijuana is such a lengthy process. Need to detox from weed? Here are the best THC(marijuana) Detox Kits to detox from weed and pass your drug test with flying colors. 👍🏻 Most effective THC detox kits for passing a drug test: 👍🏻👍🏻👍🏻 Fast Marijuana Detox Kit(extra strong): https://greenfleets.org/products/fast-thc-marijuana-detox-kit-extra-strong/?utm_source=youtube.com&utm_medium=referral&utm_campaign=weedmetabolism&utm_term=fastdetoxstrong 👍🏻👍🏻👍🏻 Green Fleets Premium 7-day THC Detox Kit: https://greenfleets.org/products/premium-detox-7-day-comprehensive-cleansing-program-p2706.html?utm_source=youtube.com&utm_medium=referral&utm_campaign=weedmetabolism&utm_term=gf7day 👩‍⚕️ The ultimate guide to passing a urine drug test: https://greenfleets.org/pass-drug-test/?utm_source=youtube.com&utm_medium=referral&utm_campaign=weedmetabolism&utm_term=detoxkits 😍 Subscribe to our channel if you want more information about the ways to detox and pass a drug test: http://www.youtube.com.com/c/ThcdetoxUsofficial Green Fleets has helped to pass a drug test for more than 50000 marijuana users. And each year, we continue to help more people to find a solution to pass urine, hair, and saliva drug tests for marijuana. We know that passing a pre-employment drug test can be very important for you. And it’s hard to find a trusted source of information. We get it! This is the reason we created Green Fleets. 😎 Visit our website for more in-depth information about ways to pass a drug test: https://greenfleets.org/?utm_source=youtube.com&utm_medium=referral&utm_campaign=weedmetabolism&utm_term=mainpage 0:00 Why it's important to understand marijuana metabolism 0:21 How much THC gets into the blood after smoking 1:18 How much THC gets into the blood after ingestion 1:32 How THC is stored in the body 2:10 Phase 1 of marijuana metabolism 2:34 Phase 2 of marijuana metabolism 3:15 Excretion of THC 3:26 Enterohepatic circulation of THC metabolites 4:07 How to speed up THC detoxification

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Anxiety is a common mental health issue that affects millions of people worldwide. It can manifest in many different ways, including feelings of worry, fear, and unease. While some people may experience mild anxiety that is manageable, others may struggle with severe anxiety that significantly impacts their daily life. Fortunately, there are various treatment options available to help manage anxiety, including therapy, medication, and lifestyle changes. One alternative treatment that has gained popularity in recent years is the use of CBD oil.

What is CBD oil?

CBD, or cannabidiol, is a compound derived from the cannabis plant. Unlike THC, another compound found in cannabis, CBD is non-psychoactive, meaning it does not produce a “high.” CBD oil is made by extracting CBD from the cannabis plant and diluting it with a carrier oil, such as coconut or hemp seed oil. It is available in various forms, including tinctures, capsules, and topicals.

Research has shown that CBD may have potential therapeutic benefits for a range of conditions, including anxiety, pain, insomnia, and epilepsy. While more research is needed to fully understand how CBD works and its effects on the body, many people have reported positive experiences with using CBD oil to manage their anxiety.

When it comes to anxiety, CBD is thought to interact with the body’s endocannabinoid system, which plays a role in regulating stress and anxiety. By interacting with receptors in the brain and immune system, CBD may help reduce feelings of anxiety and promote a sense of calm. Additionally, CBD has been shown to have anti-inflammatory and neuroprotective properties, which may also contribute to its anxiety-relieving effects.

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How can CBD oil help with anxiety?

One of the primary ways that CBD oil may help with anxiety is by reducing the activity of the amygdala, a part of the brain that is involved in the processing of emotions such as fear and stress. Studies have shown that CBD can help dampen the response of the amygdala to stressful stimuli, leading to a reduction in anxiety levels.

In addition to its effects on the amygdala, CBD has also been found to increase levels of serotonin, a neurotransmitter that plays a key role in regulating mood. Low levels of serotonin have been linked to anxiety and depression, so increasing serotonin levels with CBD could help alleviate symptoms of anxiety.

Furthermore, CBD has been shown to promote neurogenesis, the growth and development of new neurons in the brain. This process is important for maintaining healthy brain function and has been implicated in the treatment of anxiety disorders. By promoting neurogenesis, CBD may help improve brain plasticity and resilience to stress, leading to a reduction in anxiety symptoms.

Is CBD oil safe to use for anxiety?

When used correctly and in moderation, CBD oil is generally considered safe for anxiety. However, it is important to note that CBD can interact with certain medications, so it is essential to consult with a healthcare provider before starting a CBD regimen, especially if you are taking other medications.

Some people may experience side effects when using CBD oil, such as dry mouth, dizziness, changes in appetite, and diarrhea. These side effects are typically mild and temporary, but if you experience any severe or persistent side effects, you should discontinue use and consult with a healthcare provider.

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It is also important to choose high-quality CBD products from reputable sources to ensure safety and effectiveness. Look for products that have been tested by third-party laboratories for potency and purity, and always follow the manufacturer’s dosing instructions.

Conclusion

In conclusion, CBD oil shows promise as a natural remedy for anxiety due to its interactions with the endocannabinoid system, serotonin levels, and neurogenesis. While more research is needed to fully understand the mechanisms behind CBD’s anxiety-relieving effects, many people have found relief from their symptoms by using CBD oil. If you are considering trying CBD oil for anxiety, be sure to consult with a healthcare provider to determine the best approach for your individual needs.

Overall, CBD oil can be a valuable tool in managing anxiety and promoting a sense of calm and well-being.

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Professor Mike Barnes answers all your CBD questions, to help you learn more about the many health benefits of CBD, such as improved sleep, pain management and reduced anxiety. Professor Mike Barnes is the Scientific + Clinical Advisor for Serena Organics and a consultant neurologist and medical cannabis expert, dedicating his career to the development of neurological rehabilitation and medical cannabis treatment and education. Shop now: https://www.serenaorganics.com/shop Follow us: Facebook: https://www.facebook.com/SerenaOrganicsCBD Instagram: https://www.instagram.com/serenaorganicscbd LinkedIn: https://www.linkedin.com/company/serenaorganics/

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