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https://2013.psychedelicscience.org https://www.maps.org Marijuana for PTSD: Existing Evidence and MAPS' FDA-Approved Protocol Sue Sisley, MD Dr. Sisley will give an overview of MAPS' planned study of smoked or vaporized marijuana for 50 US veterans with chronic, treatment-resistant posttraumatic stress disorder (PTSD). This placebo-controlled, triple-blind, randomized crossover pilot study is the first of its kind, and will investigate the safety and efficacy of marijuana for PTSD in veterans using four marijuana strains each with a different level of D9-tetrahydrocannabinol (THC) along with a fifth strain containing equal amounts of THC (6%) and cannabidiol (CBD) (6%). PTSD symptoms will be compared across conditions during four weeks of self-administration to determine if strain potency or drug delivery method affects PTSD severity. While the U.S. Food and Drug Administration (FDA) and University of Arizona's Institutional Review Board (IRB) have accepted the protocol, the study remains blocked by the Drug Enforcement Administration and National Institute of Drug Abuse (NIDA), which refuses to sell us any of its monopoly supply of marijuana (maps.org/research/mmj/). Dr. Suzanne Sisley, MD has maintained a full-time telemedicine practice since 2009, where she employs a full array of telecommunications technology to deliver high-quality medical care to populations across rural and underserved areas of Arizona. Sue is an Institutional Member of the American Telemedicine Association and serves on the ATA's Legislative and Policy Committee. Sue also serves as Clinical Faculty at St. Joseph's Hospital and Medical Center at the MercyCare Adult Medicine Clinic for indigent patients. Dr. Sisley completed her medical degree at the University of Arizona College of Medicine and her five-year residency at Good Samaritan Regional Medical Center in Internal Medicine and Psychiatry. Sue is also Founder and CEO of Ensuring Tomorrow Productions, a non-profit organization delivering health education through music, theater, and dance. Dr. Sisley has received many recent honors including the President's Point of Light Award and the Leo B. Hart Humanitarian Award from the University of Arizona. Dr. Sisley was also honored with the Arizona Medical Association's highest award, the President's Distinguished Service Award, as well as with the Hon Kachina Award, Arizona's most prestigious recognition for volunteerism. More videos available at https://2013.psychedelicscience.org At Psychedelic Science 2013, over 100 of the world's leading researchers and more than 1,900 international attendees gathered to share recent findings on the benefits and risks of LSD, psilocybin, MDMA, ayahuasca, ibogaine, 2C-B, ketamine, DMT, marijuana, and more, over three days of conference presentations, and two days of pre- and post-conference workshops.

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It's no surprise that sleep is an incredibly important determinant of health, but did you know that getting less than 6 hours of sleep a night on a continuous basis increases the risk for a variety of health issues? Yet despite knowing the importance of a good night’s rest, so many patients you see struggle to achieve quality sleep. They may have tried other treatment methods in the past, and now they’re coming to you with questions. Could CBD help them fall asleep and stay asleep? Experts Alyson Evans and Joe LaVacca continue their CBD info series with a focused look at CBD and sleep. Join them for this discussion of the research and therapeutic applications of CBD – and get the credible information you and your clients need!

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In 2018, the FDA granted approval to cannabidiol (CBD; Epidiolex) for the treatment of rare forms of epilepsy, Dravet syndrome and Lennox-Gastaut syndrome, and while the addition was a welcomed one, this did not mark the complete understanding of the therapy’s use. Although CBD and other medications continue to be studied in some instances post-approval and often for other conditions, the need for subgroup analyses—especially in epilepsy—is paramount. As Kelly Knupp, MD, pediatric neurologist and epilepsy specialist, Children’s Hospital Colorado, pointed out in a conversation with NeurologyLive, when it comes to CBD, physicians still do not completely understand why specific subgroups of patients respond to CBD and others do not. “I think it would be worthwhile to look at that and try to figure that out,” Knupp said. The data from the clinical trials are compelling, she noted, but it’s important to remember that patients, while achieving reductions, have not been achieving seizure freedom. At the 2019 International Epilepsy Congress, June 22-26, in Bangkok, Thailand, she spoke about the use of cannabinoids in epilepsy and where they may play a role in other epilepsies.

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