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www.youshockedtv.blogspot.com Cnn Medical marijuana and the entourage effect In the early 1960s, a young postdoctoral student stumbled onto something that puzzled him. After reading the literature on cannabis, he was surprised to see that while the active compound in morphine had been isolated from opium poppies 100 years before and cocaine isolated from coca leaves around the same time, the active component of marijuana was still unknown. This simple observation launched his life's work. That young Israeli researcher, Raphael Mechoulam, is now a heavily decorated scientist, recently nominated for the prestigious Rothschild Prize. More than 50 years ago, however, he had trouble starting his scientific journey. By 1963, he determined the structure of cannabidiol (CBD), an important component of marijuana. A year later, he became the first person to isolate delta-9 tetrahydrocannabinol (THC), the psychoactive ingredient in marijuana. Over the ensuing decades, Mechoulam and his team continued to isolate numerous compounds from the cannabis plant. Their work also went a long way toward illuminating how the drug works in the brain. When Mechoulam's team identified the first known endogenous cannabinoid, a chemical actually made by the brain itself, he named it "anandamide." In the Sanskrit language, ananda means "supreme bliss," which gives us some insight into what Mechoulam thinks of cannabinoids overall. It was halfway through our long afternoon discussion that Mechoulam, now 83, pulled out a paper he had written in 1999, describing something known as "the entourage effect." Think of it like this: There are more than 480 natural components found within the cannabis plant, of which 66 have been classified as "cannabinoids." Those are chemicals unique to the plant, including delta-9-tetrahydrocannabinol and cannabidiols. There are, however, many more, including: -- Cannabigerols (CBG); -- Cannabichromenes (CBC); -- other Cannabidiols (CBD); -- other Tetrahydrocannabinols (THC); -- Cannabinol (CBN) and cannabinodiol (CBDL); -- other cannabinoids (such as cannabicyclol (CBL), cannabielsoin (CBE), cannabitriol (CBT) and other miscellaneous types). Other constituents of the cannabis plant are: nitrogenous compounds (27 known), amino acids (18), proteins (3), glycoproteins (6), enzymes (2), sugars and related compounds (34), hydrocarbons (50), simple alcohols (7), aldehydes (13), ketones (13), simple acids (21), fatty acids (22), simple esters (12), lactones (1), steroids (11), terpenes (120), non-cannabinoid phenols (25), flavonoids (21), vitamins (1), pigments (2), and other elements (9). Minister's daughter: Cannabis "a gift from God" Here is the important point. Mechoulam, along with many others, said he believes all these components of the cannabis plant likely exert some therapeutic effect, more than any single compound alone. While science has not yet shown the exact role or mechanism for all these various compounds, evidence is mounting that these compounds work better together than in isolation: That is the "entourage effect." Take the case of Marinol, which is pure, synthetic THC. When the drug became available in the mid-1980s, scientists thought it would have the same effect as the whole cannabis plant. But it soon became clear that most patients preferred smoking marijuana to taking Marinol. Researchers began to realize that other components, such as CBD, might have a larger role than previously realized. To better understand the concept of the entourage effect, I traveled to the secret labs of GW Pharmaceuticals, outside London. In developing Sativex, a cannabis-based drug to treat multiple sclerosis, the company's chairman, Dr. Geoffrey Guy, told me the company ran into some of the same obstacles that Marinol faced. More than a decade of experiments revealed that a whole plant extract, bred to contain roughly the same amounts of THC and CBD in addition to the other components in the plant, was more effective in reducing the pain and spasms of MS than a medication made of a single compound. It could be that multiple individual compounds play a role, or it could be due to their interaction in the body; it could also be combination of both, Guy said. Now, maybe this all sounds obvious. After all, eating real fruits, vegetables and other plants provides better nutrition than just taking vitamin pills with one nutrient or mineral in each. Science is showing us that we can likely say the same about cannabis. As we move forward with creating medicines, like Charlotte's Web, for the patients who can benefit from cannabis -- this is an important point to keep in mind.
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During this weeks show we speak about CBD Edibles which includes CBD Gummies, Lollies as well as introducing CBD into your food. We also touch on the cosmetic value of using cannabinoids for your skin and your body. Be sure to check out our podcast below... Visit www.Optimal-Hemp.com to Keep Up to Date with Our Podcast - Available on iTunes Podcast, TuneIn Radio, Stitcher and other main podcasting platforms. You can also visit Optimal Hemp for CBD Oils and Hemp products for Optimal Health. Our show is brought to you in partnership with the United Patient Alliance: http://www.upalliance.org/ Strong Hemp UK was originally founded as StrongVape UK, a flavoured CBD e-liquid specialist, but in December 2017 we merged with another up-and-coming brand called EV8 Life who create hand made hemp infused edibles and cosmetics. Our E-Liquid Products We feel the majority of CBD E-Liquid on the market today lack quality flavouring compared to regular nicotine based e-liquid manufacturers, so we decided to do something about it! We have taken manufacturing methods from the standard nicotine based e-liquid market and applied them to our CBD e-liquid manufacturing process. The most important part they have taken on-board is the steeping process. Steeping is allowing the flavoured e-liquid to sit in a dark room for a period of time for the flavours to mature. Think of it like a good wine, whiskey or cheese - it needs a certain amount of maturing time to become the flavour your know and love. At StrongVape UK, every bottle of e-liquid that we sell is steeped for between 4 and 12 weeks depending on how creamy the flavour is! Their goal is to have the widest range of CBD e-liquid flavours to suit all taste buds and a selection of strengths to meet everyone needs. They hope to increase their minimum steeping time to 12 weeks for all flavours and be in a position to launch flavoured CBD Drops which can be used in a RDA (rebuild-able dripping atomiser) or applied under the tongue. You can help us get there sooner by placing your next CBD e-liquid order with StrongVape UK. Strong Hemp can be found at: Website: https://www.stronghemp.uk Facebook: https://www.facebook.com/stronghempuk/ Twitter: https://twitter.com/stronghempuk Instagram: https://www.instagram.com/stronghempuk/
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Today we I am going to show you how to make a CBD cocktail. Not just 1 CBD cocktail but 3 CBD cocktails. All three CBD drinks have a low ABV. The Tropical Punch and Holiday CBD Cider each have 30 mg of CBD. Enjoy these CBD drink recipes Tropical CBD Fruit Punch 1 bottle Otto's Cider - Pineapple Passion flavor 1/2 oz. cassis, frambois and orange curacao 1 slice of lime Shake w ice This CBD Fruit Punch recipe has 30 mg of CBD Cafe au CBD - Coffee and CBD Decaff Tala Coffee 1 oz. Tala Bourbon Vanilla Sweetner 1 oz Half and Half 1 oz Bouvery Chocolate Liqeur Whipped Cream Ground Nutmeg Biscoff Cookie This Coffee and CBN butter recipe has about 5 mg of CBN. Hot CBD Holiday Cider 1 bottle Otto's Cider - Hopped Apple Flavor 1 stick cinnamon Ground Nutmeg Tablespoon of Clove Orange Slice 1 oz Koval Bourbon Whiskey Heat cider, cinnamon, grated nutmeg, orange slice and cloves. Bring to light boil and let simmer for 10 minutes. DO NOT OVER HEAT THE CIDER - the CBD will break down In a mug add one ounce Koval Bourbon Strain cinnamon, nutmeg, clove and orange slice into mug w Bourbon This CBD Cider recipe has 30 mg of CBD How to make CBD drinks Please enjoy each CBD cocktail responsibly.

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