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Importance of Decarboxylation for Cannabis Professor DeBacco Research Article ALEKSANDROV, M., & JANEVIK IVANOVSKA, E. (2022). THE ROLE AND IMPORTANCE OF THE DECARBOXYLATION PROCESS IN THE PRODUCTION OF QUALITY FULL-SPECTRUM CANNABIS EXTRACT FOR MEDICINAL PURPOSES. International Journal of Medical Sciences, 7(13-14), 119-128. https://eprints.unite.edu.mk/963/ What is Decarboxylation? All cannabinoids contained within the trichomes of raw cannabis flowers consists of cannabinoids in their acidic form and have an extra carboxyl ring or group (-COOH) attached to their chain. Decarboxylation (or “decarbing”) is where raw cannabis is heated so that the chemical structure of the acid cannabinoids changes to a neutral (non-acid) form. Acidic to Neutral Form Conversion When one states that cannabinoids are in their “acidic form”, they are referring to the chemical structure of the compound itself. A cannabinoid in its acidic form has a carboxyl group (-COOH) attached and the neutral forms, will have this carboxyl group removed. Acid = Raw plant material Neutral = Decarboxylated compound Chemical Structure Changes Transforming cannabinoid acids into their neutral forms, need to remove the carboxyl group. The weak bond holding the carboxyl group can be broken by a combination of heat and time. Why Does Cannabis need Carboxylation? This process essentially converts the chemicals into an “active” form by increasing the bodies ability to absorb and bind to the molecules. Essentially the body can use the “active” form. Carboxylation happens naturally when the plant material is ignited. Importance of Decarboxylation: THCA vs THC While THCA is the non-psychoactive (not decarboxylated form) precursor to THC (the decarboxylated form), it does not bind to the CB1 and CB2 receptors. Note: THCA binds with other cannabinoids receptors in the endocannabinoid system. Although THCA possesses therapeutic effects, like anti-inflammatory and neuroprotective qualities, it is not in its most beneficial or psychoactive form. Decarboxylation Requires Heat and Time The two main catalysts for decarboxylation to occur are heat and time. Drying and curing cannabis over time will cause partial decarboxylation to occur. While heat is needed to decarboxylate the acids into the active form of cannabinoids our bodies can use, extreme temperatures can destroy many of the important plant materials that contribute to positive health outcomes, like terpenes. Use Minimal Temperature to Preserve Terpenes Cannabis Trim Trim is what is removed from the final flower after harvest. Trim includes sugar leaves, bits of cut-off buds, and knocked off trichomes, or kief. Kief Explained When trichomes dry and break off of the plant, they become kief. Kief, because it has oxidized and loses its freshness when separated from the plant buds, usually has a darker color than trichomes, ranging from light gold to brown. It has a powdery appearance and a texture that is somewhat sticky, though less so than trichomes on a bud. Kief tends to decarb faster than an intact flower. Other Factors of Variability… Variety of Cannabis Used Each type of cannabis contains different amounts and ratios of different cannabinoids and terpenes which impact the optimum decarboxylation time and temperatures. This can also be impacted by the physical structure of the flower Age (Freshness) of Product There will be noticeable differences in the final product depending on the age (freshness) of the material you start with. Remember: The decarboxylation process only converts the acidic form to the bioactive neutral form, it does not “create” the CBD or THC molecule. If the flower consistency is widely variable grinding up the plant material will increase the uniformity of the decarboxylation process. General Key Points Need to have in mind that, at higher temperatures, Kief and Hash tend to decarboxylate faster than dried flowers. High CBD strains tend to decarboxylate a bit slower than those with high THC content Three Main Decarboxylating Factors for Cannabis The most important parameters to perform a good decarboxylation process are… Time (duration) Temperature Quality decarboxylation equipment Suggestions for Decarboxylating Your Cannabis From the review of published literature data… Highest concentration of THC (about 15 mg/g) is obtained when the material is decarboxylated at 122°C for 27 minutes. Converting CBDA to CBD, a higher temperature is required, about 150°C, for about 30 minutes. To decarboxylate Kief or Hash in an oven, bake it for 10 minutes at 300°F (149°C). Link to Lecture Slides: https://drive.google.com/file/d/1l4M8JxgL0GUVZO8Cbr15ncUTSSa7QduO/view?usp=drive_link *Due to the description character limit the full work cited for "Importance of Decarboxylation for Cannabis" can be viewed at... https://docs.google.com/document/d/1d7MFDC65xVjxHVmaqPvKlzLVNLidOfyw/edit?usp=drive_link&ouid=104237452697237972847&rtpof=true&sd=true
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If you have already seen my basic How To Make Cannabis Oil in 7 Easy Steps at 7easysteps.org, you should find this video even more interesting! If you are just stumbling upon my tutorials for the first time, please know, I am not a chemist, I am not a Dr. I am a patient turned healer and I needed to quickly learn how to make oil. WARNINGS: USE WELL VENTILATED AREA!!! NO SMOKING WHILE MAKING OIL!!!!! DONT REPLACE ETHYL with ISOPROPYL ALCOHOL!!! DO NOT PURCHASE ANY OIL OFF OF THE COMMENTS IN THIS SITE!!!! For winterizing, it is very important you do not let your tincture warm to below 32degrees Farenheit, otherwise you will not have a chance to filter out the lipids that melt! Need a reliable source for incredible whole plant terpene rich hemp extract CBD oil? Contact [email protected] today! (US ONLY) The beaker I used is a 500ml erlenmeyer filter flask For dosing: Everyone is different, therefore answers vary. Contact [email protected] for guidance on how to apply cannabinoid therapy to your condition. For smoking: sure you can smoke this product, this is not our goal here. For sublingual: best to homogenize with a healthy fat such as organic unrefined coconut oil, organic cacao butter, organic butter (will turn rancid after some time), Ghee (clarified butter), honey, etc. For suppository: " " " " " " organic unrefined coconut oil or even better organic cacao butter (stays solid longer than coconut oil) For capsules: simply fill caps or homogenize with healthy fat such as organic unrefined coconut oil and than fill your caps to desired amount. For topical: simply apply to designated area or first homogenize with healthy fat for even better delivery! For Step 7: You can purge most of your alcohol and finish off the end of the tincture by letting it evaporate in a pyrex dish or cooking in a pot over a double boil which will be consistently around 200-210degrees. The lower the temp you use to purge, the more terpenes you will retain! If you enjoyed this video, please make a small donation at GuerillaHealer.org! If you want to learn more about applying cannabinoid therapy to your ailment, I am available for consultation. Please email [email protected] If you are poverty level and need to learn more, you can utilize my charity, GuerillaHealer, by emailing [email protected] camera work by Jordan Meunch of Monark Clothing Winterizing tech taught to BURNTmd by Ryan Eades If you find my video helpful please make a donation to GuerillaHealer.org help me expand my efforts to help others Music by: 1st song by Touchphonics 2nd song by Touchphonics 3rd song by E-train 4th song by Es-k 5th song by Mike Cash & BURNTmd Rest in power all our lost ones Our actions today help their spirits live on! #LiveLoveLife
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Watch the official music video for 7 Years by Lukas Graham from the self-titled album. 🔔 Subscribe to the channel: https://youtube.com/c/LukasGraham?sub_confirmation=1 Listen to Share That Love (feat. G-Eazy) here: https://lukasgraham.lnk.to/sharethatlove 3 (The Purple Album) available here: https://lukasgraham.lnk.to/3ThePurpleAlbum Directed by René Sascha Johannsen Produced by The Woerks & Seven Pictures "A mix of Christiania, Copenhagen and Los Angeles is combined to give you a beautiful imagery to help the song along. I really hope you like it." - Lukas Graham Follow Lukas Graham: Facebook: https://facebook.com/LukasGraham Twitter: https://twitter.com/LukasGraham Instagram: https://instagram.com/LukasGraham Spotify: https://smarturl.it/LukasGrahamSpotify Lukas Graham is a singer-songwriter renowned for his hits “7 Years,” “Love Someone,” “Mama Said,” “You’re Not There,” “Criminal Mind,” “Drunk In The Morning,” and “Lie.” He worked with artists like G-Eazy, Wiz Khalifa, Brandon Beal, and Kelsea Ballerini — amassing billions of global streams and achieved multi-platinum certifications across multiple continents. Lyrics: Once I was seven years old my mama told me, Go make yourself some friends or you'll be lonely Once I was seven years old It was a big, big world but we thought we were bigger Pushing each other to the limits, we were learning quicker By eleven smoking herb and drinking burning liquor Never rich so we were out to make that steady figure Once I was eleven years old my daddy told me, Go get yourself a wife or you'll be lonely Once I was eleven years old I always had that dream like my daddy before me So I started writing songs, I started writing stories Something about that glory just always seemed to bore me ‘Cause only those I really love will ever really know me Once I was twenty years old my story got told Before the morning sun when life was lonely Once I was twenty years old I only see my goals I don't believe in failure ‘Cause I know the smallest voices they can make it major I got my boys with me, at least those in favor And if we don't meet before I leave I hope I'll see you later Once I was twenty years old my story got told I waswriting 'bout everything I saw before me Once I was twenty years old Soon we'll be thirty years old, our songs have been sold We'vetraveled around the world and we're still roaming Soon we'll be thirty years old I'm still learning about life, my woman brought children for me So I can sing them all my songs and I can tell them stories Most of my boys are with me, some are still out seeking glory And some I had to leave behind, my brother I'm still sorry Soon I'll be sixty years old, my daddy got sixty-one Remember life and then your life becomes a better one I made a man so happy when I wrote a letter once I hope my children come and visit once or twice a month Soon I'll be sixty years old, will I think the world is cold Or will I have a lot of children who can warm me Soon I'll be sixty years old #OfficialMusicVideo #LukasGraham #7Years #WeAreWarnerRecords
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Dr. Matthew Dawson of Wild Health and Wild Health CBD joins Dr. Barrett to discuss why they choose CBD and what the Wild Health CBD brand is innovating! Dr. Barrett looked around at all the different CBD products out there and feels that Wild Health stands above and beyond. Learn about the extraction methods used and why quality CBD works so well for pre and post op treatments. Hear about how CBD can actually curb the need to prescribe opioids and other over the counter options that can make patient conditions worse. CBD itself is doing great things but, the quality of the product and the teams behind it all are key. Dr. Dawson explains everything from mass spectrometry methods to how they are able to test it all for contamination. Be sure to tune in and learn everything you need to know about CBD! Please visit www.wildhealth.com for info on the medical practice. www.wildhealthcbd.com is where you can purchase products and receive a 20% discount with PROMO CODE: drbarrett Visit our website at www.drdanielbarrett.com for more information. #CBD #WildHealth #NaturalPlasticSurgeon
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