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On this episode of the She’s Healthy podcast your host and Nurse Practitioner, Lori Aikman, looks at the research to see… Which is better for weight loss semaglutide (Wegovy) or tirzepatide (Zepbound)? If you're a woman who is struggling to lose weight, maybe all the things you used to do like diet and exercise aren't working and you're looking for more. If you're considering taking one of these medications to help your stubborn weight loss, this is an episode you won't want to miss. Key Takeaways: Mechanism of Action: Lori reviews how both semaglutide and tirzepatide work to induce weight loss. If you missed the details, check out the first episode for an in-depth discussion. Approval Timeline: Semaglutide received FDA approval for treating obesity before tirzepatide. Tirzepatide was FDA approved for obesity on 11/8/23. Clinical Trials: Explore the results of the STEP trials, focusing on semaglutide's effectiveness for obesity. Learn about the SURPASS trials that studied tirzepatide's impact on patients with diabetes, and get a sneak peek into the upcoming SURMOUNT trials examining tirzepatide's efficacy for obesity in both diabetic and non-diabetic patients. Pharmaceutical Source: Both semaglutide and tirzepatide injections are products of the renowned pharmaceutical company, Eli Lilly. Prescribing Guidelines: Understand the obesity prescribing guidelines, emphasizing that these medications are intended for individuals with a BMI greater than 30 or a BMI greater than 27 with weight-related comorbidities such as diabetes, pre-diabetes, high blood pressure, high cholesterol, cardiovascular disease, etc. SURMOUNT-1 Trial: Delve into the findings of the SURMOUNT-1 trial, exploring the effectiveness of various tirzepatide doses compared to a placebo for weight loss. Discover that weight loss increases with higher doses of tirzepatide. Comparison Study: Gain insights from the study "Weight loss with subcutaneous semaglutide versus other glucagon-like peptide 1 receptor agonists in type 2 diabetes." Find out how tirzepatide outperformed semaglutide, dulaglutide, exenatide, and liraglutide in terms of weight loss. Appetite Reduction: Uncover takeaways from the study "Tirzepatide Reduces Appetite, Energy Intake, and Fat Mass in People With Type 2 Diabetes." Cost-Effective Options: Lori suggests a cost-effective alternative – getting these medications from a compounding pharmacy. Whether you're on a weight loss journey or simply curious about these medications, Lori provides valuable insights to guide your decisions. Tune in to the She’s Healthy podcast and stay informed about optimizing your health in your 30s and 40s! Curious about working with Lori? Click here to book a 15 Minute Connection Call: https://crownexecutivehealth.practicebetter.io/#/631766a4a7504499f968aef3/bookings?s=63f18e116f764b1753415af8 Check out the website: http://www.queenbeemedicine.com Follow us on Instagram: https://www.instagram.com/queenbeemedicine/ https://www.instagram.com/loriaikman/

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Why don’t more people take the weight loss medications currently on the market? Subscribe to NutritionFacts.org’s free newsletter to receive our B12 infographic that covers the latest research takeaways and Dr. Greger’s updated recommendations: https://nutritionfacts.org/subscribe/ The video I mentioned is Brown Fat: Losing Weight Through Thermogenesis (https://nutritionfacts.org/video/brown-fat-losing-weight-through-thermogenesis). Stay tuned for Are Weight Loss Pills Effective? (http://nutritionfacts.org/video/are-weight-loss-pills-effective) So what does work for weight loss? That’s the topic of my new book, How Not to Diet. You can preorder now at https://nutritionfacts.org/how-not-to-diet/, and you’ll be among the first to get it when it’s out in December. (All proceeds I receive from my books are donated to charity.) In the meantime, you can find more on weight loss in: • Eating More to Weigh Less (https://nutritionfacts.org/video/eating-more-to-weigh-less) • How to Prevent Prediabetes in Children (https://nutritionfacts.org/video/how-to-prevent-prediabetes-in-children/) • Nutrient Dense Approach to Weight Management (https://nutritionfacts.org/video/nutrient-dense-approach-to-weight-management/) • How Much Exercise to Sustain Weight Loss (https://nutritionfacts.org/video/how-much-exercise-to-sustain-weight-loss/) • Keep Your Waist Circumference to Less than Half Your Height (https://nutritionfacts.org/video/keep-your-waist-circumference-to-less-than-half-your-height/) • Does Apple Cider Vinegar Help with Weight Loss? (https://nutritionfacts.org/video/apple-cider-vinegar-help-weight-loss/) • Can Morbid Obesity Be Reversed through Diet? (https://nutritionfacts.org/video/can-morbid-obesity-be-reversed-through-diet) • The Weight Loss Program that Got Better with Time (https://nutritionfacts.org/video/the-weight-loss-program-that-got-better-with-time/) Have a question about this video? Leave it in the comment section at http://nutritionfacts.org/video/are-weight-loss-pills-safe and someone on the NutritionFacts.org team will try to answer it. Want to get a list of links to all the scientific sources used in this video? Click on Sources Cited at http://nutritionfacts.org/video/are-weight-loss-pills-safe. You’ll also find a transcript and acknowledgements for the video, my blog and speaking tour schedule, and an easy way to search (by translated language even) through our videos spanning more than 2,000 health topics. If you’d rather watch these videos on YouTube, subscribe to my YouTube Channel here: https://www.youtube.com/subscription_center?add_user=nutritionfactsorg Thanks for watching. I hope you’ll join in the evidence-based nutrition revolution! -Michael Greger, MD FACLM Captions for this video are available in several languages. To find yours, click on the settings wheel on the lower-right of the video and then "Subtitles/CC." Do you have feedback about the translations in this video? Please share it here along with the title of the video and language: https://nutritionfacts.zendesk.com/hc/requests/new To view the subtitles in transcript format, click on the ellipsis button below the video, choose "Open transcript", and select the language you'd like to view them in. Image source: e-Magine Art / flickr https://NutritionFacts.org • Subscribe: https://nutritionfacts.org/subscribe • Donate: https://nutritionfacts.org/donate • Podcast : https://nutritionfacts.org/audio • Facebook: www.facebook.com/NutritionFacts.org • Twitter: www.twitter.com/nutrition_facts • Instagram: www.instagram.com/nutrition_facts_org • Books (including the NEW How Not to Diet Cookbook): https://nutritionfacts.org/books • Shop: https://drgreger.org

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First workout of 2023 - I thought a sweaty HIIT workout would be a good start.♥︎ You can burn lots of calories, release looots of endorphins (the happy hormones) and lose fat within only 10 minutes + this workout has an afterburn effect, means your body will continue burning calories even after the workout! It'll be fun, I promise. Hit the play button and let's get fit instantly! :) ▪️ Intensity: High Intensity ▪️ Recommendations: • You can do this workout everyday to lose weight. • For more calorie burn, combine it with my other cardio/HIIT workouts and for toning your muscles, you can continue with my strength workous. __________________________________________ ➞ INSTAGRAM: https://www.instagram.com/eylmbc/ (Free Weekly Workout Plans & Challenges!♥︎) use #EylemAbaci if you want me to see your pics and videos! ➞ BLOG: http://eylemabaci.com/ ✉️ PR / BUSINESS INQUIRIES: [email protected] 🎵 My Spotify Workout-Playlist: https://sptfy.com/M0Xd 🎵 Music provided by Epidemic Sound https://www.epidemicsound.com/referral/u7y20x/ __________________________________________ Disclaimer: In order to avoid any injury or harm, you need to check your health before doing the exercises. Performing any fitness exercises without supervision, is at your own risk. Please take professional advices of a fitness professional. Eylem Abaci will not be responsible or liable for any injury or harm you sustain as a result of this video.

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