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Professor Barry Borlaug presents the SUMMIT trial on the use of the GIP / GLP-1 receptor dual agonist in patients with obesity-associated Heart-Failure with Preserved Ejection Fraction, which has been published in New Engl J Med 2024 and elected the most important study in cardiology and lipidology 2024 by MARKUS at HOMe. Dr. Borlaug is Professor of Medicine and Director, Circulatory Failure Research, Division of Cardiovascular Diseases, and Chair for Research, Division of Circulatory Failure, Department of Cardiovascular Medicine at the Mayo Clinic, Rochester, Minnesota. He is a global leader in studies on mechanisms, diagnosis and treatment of heart failure, particularly heart failure with preserved ejection fraction (HFPEF). The interview was recorded on January 16th, 2025. Moderators: Prof. Dr. Dr. Stephan Schirmer (Kaiserslautern, Germany), Prof. Dr. Florian Custodis (Saarbrücken, Germany) and Prof. Dr. Gunnar Heine (Frankfurt, Germany). Articles discussed: GLP-1 receptor agonists are promising but unproven treatments for alcohol and substance use disorders. Leggio L, Hendershot CS, Farokhnia M, Fink-Jensen A, Klausen MK, Schacht JP, Simmons WK. Nat Med 2023 doi: 10.1038/s41591-023-02634-8 Tirzepatide Reduces LV Mass and Paracardiac Adipose Tissue in Obesity-Related Heart Failure: SUMMIT CMR Substudy. Kramer CM, Borlaug BA, Zile M MR, Ruff D, DiMaria JM, Menon V, Ou Y, Zarante AM, Hurt KC, Murakami M, Packer M; SUMMIT Trial Study Group. J Am Coll Cardiol 2024 doi: 10.1016/j.jacc.2024.11.001 Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity. Packer M, Zile MR, Kramer CM, Baum SJ, Litwin SE, Menon V, Ge J, Weerakkody GJ, Ou Y, Bunck MC, Hurt KC, Murakami M, Borlaug BA; SUMMIT Trial Study Group. N Engl J Med 2024 doi: 10.1056/NEJMoa2410027 Effects of tirzepatide on circulatory overload and end-organ damage in heart failure with preserved ejection fraction and obesity: a secondary analysis of the SUMMIT trial. Borlaug BA, Zile MR, Kramer CM, Baum SJ, Hurt K, Litwin SE, Murakami M, Ou Y, Upadhyay N, Packer M. Nat Med 2024 doi: 10.1038/s41591-024-03374-z Evidence Supporting the Existence of a Distinct Obese Phenotype of Heart Failure With Preserved Ejection Fraction. Obokata M, Reddy YNV, Pislaru SV, Melenovsky V, Borlaug BA. Circulation 2017 doi: 10.1161/CIRCULATIONAHA.116.026807 An evidence-based screening tool for heart failure with preserved ejection fraction: the HFpEF-ABA score. Reddy YNV, Carter RE, Sundaram V, Kaye DM, Handoko ML, Tedford RJ, Andersen MJ, Sharma K, Obokata M, Verbrugge FH, Borlaug BA. Nat Med 2024 doi: 10.1038/s41591-024-03140-1 A Simple, Evidence-Based Approach to Help Guide Diagnosis of Heart Failure With Preserved Ejection Fraction. Reddy YNV, Carter RE, Obokata M, Redfield MM, Borlaug BA. Circulation 2018 doi: 10.1161/CIRCULATIONAHA.118.034646 How to diagnose heart failure with preserved ejection fraction: the HFA-PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC). Pieske B, Tschöpe C, de Boer RA, Fraser AG, Anker SD, Donal E, Edelmann F, Fu M, Guazzi M, Lam CSP, Lancellotti P, Melenovsky V, Morris DA, Nagel E, Pieske-Kraigher E, Ponikowski P, Solomon SD, Vasan RS, Rutten FH, Voors AA, Ruschitzka F, Paulus WJ, Seferovic P, Filippatos G. Eur J Heart Fail 2020 doi: 10.1002/ejhf.1741 Dapagliflozin Enhances Arterial and Venous Compliance During Exercise in Heart Failure With Preserved Ejection Fraction: Insights From the CAMEO-DAPA Trial. Tada A, Burkhoff D, Naser JA, Harada T, Pourmussa B, Reddy YNV, Jensen MD, Carter RE, Demmer RT, Testani JM, Chirinos JA, Borlaug BA. Circulation 2024 doi: 10.1161/CIRCULATIONAHA.124.068788 Cardiac and Metabolic Effects of Dapagliflozin in Heart Failure With Preserved Ejection Fraction: The CAMEO-DAPA Trial. Borlaug BA, Reddy YNV, Braun A, Sorimachi H, Omar M, Popovic D, Alogna A, Jensen MD, Carter R Circulation 2023 doi: 10.1161/CIRCULATIONAHA.123.065134

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Are you following a Weight Watchers diet but also interested in the keto lifestyle? You may be wondering how to integrate these two popular approaches to weight loss and health. One way to do this is by incorporating Weight Watchers Keto Gummies into your daily routine. These gummies are a convenient and delicious way to enjoy the benefits of both Weight Watchers and keto. In this article, we will explore how you can incorporate these gummies into your diet and make the most of their unique combination of ingredients.

Benefits of Weight Watchers Keto Gummies

First, let’s take a look at the benefits of Weight Watchers Keto Gummies. These gummies are specifically designed to be low in carbs and sugar, making them a great option for those following a keto diet. They are also portion-controlled, which can help you stay on track with your Weight Watchers points. Additionally, these gummies are packed with nutrients and antioxidants, making them a healthy snack option.

Weight Watchers Keto Gummies are also convenient and portable, making them easy to take on the go. Whether you’re heading to work, the gym, or running errands, these gummies are a great option for staying satisfied between meals. They are also available in a variety of flavors, so you can choose the ones that appeal to your taste buds.

How to Incorporate Weight Watchers Keto Gummies Into Your Diet

Now that you know the benefits of Weight Watchers Keto Gummies, let’s discuss how you can incorporate them into your diet. One way to enjoy these gummies is as a snack between meals. This can help to curb your cravings and keep you satisfied until your next meal. You can also enjoy these gummies as a dessert after dinner. They provide a sweet treat without all the added sugar and carbs.

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Another way to incorporate Weight Watchers Keto Gummies into your diet is to use them as a topping for salads or yogurt. This can add a burst of flavor and sweetness to your meal without adding unnecessary calories. You can also chop up the gummies and mix them into your favorite smoothie or protein shake for an extra boost of nutrients.

Tips for Making the Most of Weight Watchers Keto Gummies

To make the most of Weight Watchers Keto Gummies, it’s important to practice portion control. While these gummies are low in carbs and sugar, it’s still important to enjoy them in moderation. Be mindful of your portion sizes and avoid overindulging. It’s also a good idea to track your gummy consumption in your Weight Watchers app to ensure you’re staying within your daily points allowance.

In addition, be sure to drink plenty of water throughout the day when enjoying Weight Watchers Keto Gummies. Staying hydrated can help you feel full and satisfied, reducing the temptation to snack on unhealthy foods. Water can also help to flush out toxins and aid in digestion, keeping your body healthy and functioning properly.

Final Thoughts on Weight Watchers Keto Gummies

Integrating keto into a Weight Watchers diet can be a successful way to lose weight and improve your overall health. Weight Watchers Keto Gummies are a convenient and delicious way to enjoy the benefits of both approaches. By following the tips outlined in this article, you can make the most of these gummies and stay on track with your weight loss goals. Whether you enjoy them as a snack, dessert, or topping, Weight Watchers Keto Gummies are a versatile option for those looking to enhance their diet and lifestyle.

Overall, Weight Watchers Keto Gummies are a great addition to any weight loss plan. They are low in carbs and sugar, packed with nutrients, and convenient to enjoy on the go. By incorporating these gummies into your diet and following the tips provided, you can make the most of their unique combination of benefits. Whether you’re following a keto diet, a Weight Watchers plan, or both, these gummies can help you stay on track and reach your weight loss goals.

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Are you looking for a convenient and effective way to maintain your ketogenic diet and achieve your weight loss goals? Optiplex Keto Gummies may be the perfect solution for you. These gummies are specially formulated to support your body’s natural ketosis process, making it easier for you to stay in ketosis and burn fat for energy. With a delicious taste and easy-to-take form, Optiplex Keto Gummies are a must-have for anyone following a keto lifestyle.

Benefits of Optiplex Keto Gummies

Optiplex Keto Gummies are packed with powerful ingredients that can help you optimize your keto diet and achieve your weight loss goals. Here are some of the key benefits of these gummies:

1. Enhanced Ketosis: The ingredients in Optiplex Keto Gummies are designed to help your body enter and maintain ketosis, the state where your body burns fat for fuel instead of carbs. By promoting ketosis, these gummies can help you reach your weight loss goals faster.

2. Increased Energy Levels: When your body is in ketosis, it can tap into its fat stores for a steady source of energy. This can lead to increased energy levels and improved focus throughout the day, helping you stay productive and active.

3. Appetite Control: Optiplex Keto Gummies contain ingredients that can help curb your cravings and suppress your appetite. This can make it easier for you to stick to your keto diet and avoid overeating, leading to faster and more sustainable weight loss results.

How to Use Optiplex Keto Gummies

Using Optiplex Keto Gummies is simple and convenient. Just take the recommended dosage of gummies each day, preferably with a meal. These gummies can be taken on their own or as part of your keto meal plan. For best results, be sure to drink plenty of water throughout the day and maintain a healthy lifestyle.

It is important to note that individual results may vary, and it is always a good idea to consult with a healthcare professional before starting any new supplement regimen, especially if you have any underlying health conditions or are taking medication.

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Overall, Optiplex Keto Gummies are a convenient and effective way to support your keto lifestyle and achieve your weight loss goals. With their powerful ingredients and delicious taste, these gummies make it easy to stay on track with your diet and see real results. Try Optiplex Keto Gummies today and experience the benefits for yourself!

Frequently Asked Questions

1. Are Optiplex Keto Gummies safe to use?

Yes, Optiplex Keto Gummies are made with natural ingredients and are generally safe for most people to use. However, it is always recommended to consult with a healthcare professional before starting any new supplement regimen, especially if you have any underlying health conditions or are taking medication.

2. How quickly can I expect to see results with Optiplex Keto Gummies?

Results may vary from person to person, but many users report noticing improvements in their energy levels, weight loss, and overall well-being within a few weeks of using Optiplex Keto Gummies consistently.

3. Can I take Optiplex Keto Gummies if I am not following a keto diet?

While Optiplex Keto Gummies are specifically designed to support a keto lifestyle, they can still be beneficial for anyone looking to enhance their energy levels, control their appetite, and achieve their weight loss goals. However, for optimal results, it is recommended to follow a ketogenic diet while taking these gummies.

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