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To cite: Senni N, Savall M, Cabrerizo Granados D, et al. Gut 2019;68:322-334. Read the full article here: http://dx.doi.org/10.1136/gutjnl-2017-315448. Objectives: CTNNB1-mutated hepatocellular carcinomas (HCCs) constitute a major part of human HCC and are largely inaccessible to target therapy. Yet, little is known about the metabolic reprogramming induced by β-catenin oncogenic activation in the liver. We aimed to decipher such reprogramming and assess whether it may represent a new avenue for targeted therapy of CTNNB1-mutated HCC. Conclusions: FAO induced by β-catenin oncogenic activation in the liver is the driving force of the β-catenin-induced HCC. Inhibiting FAO by genetic and pharmacological approaches blocks HCC development, showing that inhibition of FAO is a suitable therapeutic approach for CTNNB1-mutated HCC.

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Natural Appetite Hack That Actually Works?! 💊🌿 Injectable GLP-1 peptides aren't the only way to curb cravings. Calocurb is an oral pill that suppresses hunger naturally. 💡 This lil’ powerhouse helps your body say “bye-bye” to those sneaky cravings, so you can own your health goals without feeling deprived. 💃🏻✨ 💝 PS: Want a more feminine approach to biohacking? Come join my private women-only space: The Feminine Flow Collective [Link in Bio] 💕 We vibe, learn, & level up—TOGETHER #Calocurb #GLP1 #AppetiteSuppression #CravingsControl #FatLoss #WeightLossMedication #FeminineEnergy #WomensHealth #ObesityMedicine

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Outside the box fit pro, Ellen Barrett, shows you how to energize with breathing. Better breathing equals better energy levels. Sneak in Some Skinny is a video blog encouraging women align with Mother Nature to look, feel and be their best. www.sneakinsomeskinny.com

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Discover How You Can Gain Up To 5... 10... 15... & Even 20 Pounds Of Muscle In Just 21 Days With The Fastest & Easiest Cyclical Bulking Method: http://go.vincedelmontefitness.com/go/3202/YT-06-06-2013-DES1 Can you lose fat without losing weight on the scale? Find out in this episode of ATSGS! Only certain people can...watch the video to find out if you're one of those people. If you want to learn how to lose weight click the show more button. I will give you some cool ways to lose weight. - Find a GOOD training partner. A good training partner will not only kick your butt in the gym, but will keep you motivated throughout your entire workout session. This one tip alone could help you bust through a weigh loss plateau. - Get more vitamin D. Studies have shown that just by having adequate amounts of vitamin D in your diet, it can really help you lose weight fast. If you'd rather not supplement, at least get outside for an hour a day. - Decrease your rest periods. Too many people these days get a membership to the gym, only to end up socializing with everyone there. Can you lose weight socializing all the time? Maybe at first, but I PROMISE you will eventually have a really hard time losing weight fast. - Of course a weight loss diet is a must, if you want to burn fat. But I highly recommend NOT following any fad diets. A good diet is one with without any processed foods, high in proteins, fats, fiber and veggies. Also if fat loss is your main goal keep the carb intake low. If you do this you won't have to worry about counting calories to lose weight. LIKE this video if these tips to lose weight were helpful! If you have any questions on how to lose weight let me know in the comments section below! I will help you out ASAP. Vince DelMonte Honors Kinesiology Degree PICP Level 1 and 2 Certified BioSignature Modulation Practitioner PIMST & FFT Certified Precision Nutrition Certified WBFF Pro Fitness Model Have a friend that's always asking, "help me lose weight!"? Here's the link to share: http://youtu.be/Pu8bxQHuN3M PS: Imagine for a moment, that it's 21 days from today and you've already added 2 inches to your chest, an inch to your arms, broader shoulders and up to 12 pounds of rock-solid muscle to your frame. Guys are asking you "what you're on" and girls are giving you... that look. There is one problem we must address right now... CONTINUE READING HERE: http://go.vincedelmontefitness.com/go/3202/YT-06-06-2013-DES2

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