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Learn more about becoming an Insider: https://www.benbikman.com Dr. Bikman’s Metabolic Classroom lecture this week explores the physiological role and implications of GLP-1 (glucagon-like peptide-1) and the GLP-1 receptor agonist drugs used for type 2 diabetes management and weight loss. Ben begins by explaining GLP-1 as a hormone produced in the intestines in response to food. It plays a vital role in slowing gastric emptying, suppressing glucagon, and regulating appetite by signaling fullness to the brain. These mechanisms contribute to its effects on stabilizing blood sugar and enhancing insulin sensitivity. He then delves into GLP-1 receptor agonists, drugs that mimic GLP-1’s actions, including semaglutide, liraglutide, and others marketed under brand names like Ozempic and Wegovy. These medications have gained fame for their weight loss efficacy, often leading to reductions in body weight by 15% or more. However, Ben emphasizes that weight loss involves not only fat but also lean mass, raising concerns about muscle loss and metabolic health. Additionally, he discusses the medications’ side effects, including depression, anhedonia, and potential long-term complications like fat cell development and gallstones. The lecture also addresses the diminishing returns of these drugs over time, noting that their efficacy in reducing cravings and improving eating control tends to wane after prolonged use. Dr. Bikman highlights that education on healthy eating and resistance training is crucial for maintaining health outcomes, as reliance solely on medication can lead to unintended consequences, such as increased fat regain after discontinuation. Ben concludes by stressing the importance of combining these drugs with a low-carb diet and resistance training to minimize muscle loss and optimize long-term outcomes. He encourages using the lowest effective dose and underscores the need for lifestyle changes to complement pharmacological interventions. Show Notes/References: For complete show notes and references referred to in this episode, we invite you to become a Ben Bikman Insider subscriber. As a subscriber, you’ll enjoy real-time, livestream Metabolic Classroom access which includes live Q&A with Ben, ad-free Metabolic Classroom Podcast episodes, show notes and references, Ben’s Research Reviews Podcast, and a searchable archive that includes all Metabolic Classroom episodes and Research Reviews. Learn more about becoming an Insider on our website: https://www.benbikman.com (Auto-Translate Note: You can click the gear icon at the bottom of this video to auto-translate captions. For example, to translate into Polish, select Subtitles, choose Auto-Translate, then first choose English, then choose Auto-Translate again, then choose Polish.) #GLP1 #WeightLossDrugs #Ozempic #Wegovy #Semaglutide #Liraglutide #Type2Diabetes #DiabetesManagement #InsulinResistance #WeightLossTips #MetabolicHealth #DrBenBikman #MetabolicScience #MuscleHealth #MentalHealthMatters #LowCarbDiet #FatLoss #HealthRisks #DiabetesDrugs #ScienceExplained Timestamps: 00:01 - Introduction and Overview 02:16 - What is GLP-1? 03:15 - GLP-1's Role in Metabolism 05:08 - Appetite Regulation and Insulin Effects 07:05 - GLP-1 and Blood Sugar Management 08:10 - Introduction to GLP-1 Receptor Agonists 09:05 - Key GLP-1 Drugs and Brand Names 12:04 - Weight Loss Mechanisms of GLP-1 Drugs 14:06 - Mental Health Risks of GLP-1 Drugs 16:15 - Muscle Loss Concerns 18:24 - Fat Cell Differentiation and Regain Risk 20:07 - Long-Term Diminishing Effects 25:30 - Pancreatitis and Gallstones 29:11 - Closing Thoughts and Recommendations Ben’s favorite yerba maté and fiber supplement: https://ufeelgreat.com/usa/en/c/1BA884 Ben’s favorite meal-replacement shake: https://gethlth.com (discount: BEN10) Ben’s favorite electrolytes (and more): https://redmond.life (discount: BEN15) Ben’s favorite allulose source: https://rxsugar.com (discount: BEN20) Ben’s favorite health check-up for women: https://choosejoi.co/drben15 (discount: DRBEN15) Ben’s favorite health check-up for men: https://blokes.co/drben15 (discount: DRBEN15) Ben’s favorite exogenous ketone: https://www.americanketone.com (discount: Ben10) Other products Ben likes: https://www.amazon.com/shop/benbikmanphd Learn more about becoming an Insider on our website: https://www.benbikman.com

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Interview with Dennis J. Rivet II, MD, author of GLP-1 Receptor Agonists in Idiopathic Intracranial Hypertension. Hosted by Cynthia E. Armand, MD. Related Content: GLP-1 Receptor Agonists in Idiopathic Intracranial Hypertension https://jamanetwork.com/journals/jamaneurology/fullarticle/10.1001/jamaneurol.2025.2020?utm_campaign=podcasts&utm_medium=social&utm_source=youtube&utm_content=public Podcast was originally published on July 14, 2025. https://edhub.ama-assn.org/jn-learning/audio-player/10.1001/jamaneurol.2025.2895?utm_campaign=podcasts&utm_medium=social&utm_source=youtube&utm_content=public --------------------------------------------------------------------------------- Follow JAMA Neurology Author Interviews on: Youtube: https://www.youtube.com/playlist?list=PL4VOPuLXRs1d82BfwCujd2YHcLuRv_3yl Apple Podcasts: https://podcasts.apple.com/us/podcast/jama-neurology-author-interviews-covering-research/id1227001063 Spotify: https://open.spotify.com/show/7y27rTouoAneNIKplLcqMu Pocket Casts: https://pca.st/NL2D Your podcast app of choice: https://pod.link/1227001063 Website: https://jamanetwork.com/journals/jamaneurology/pages/jama-neurology-author-interviews --------------------------------------------------------------------------------- For more from JAMA • https://www.jama.com • https://www.facebook.com/JAMAJournal • https://www.twitter.com/JAMA_Current • https://www.linkedin.com/company/jamanetwork Follow the JAMA Network • https://www.jamanetwork.com • http://www.jamanetworkaudio.com • https://www.facebook.com/JAMANetwork • https://www.twitter.com/JAMANetwork • https://www.instagram.com/JAMANetwork • https://www.pinterest.com/JAMANetwork

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Power Keto Gummies have been gaining popularity in the market as a weight loss supplement that claims to help users achieve their fitness goals. With the rise in demand for ketogenic products, many people have turned to keto gummies as a convenient and tasty way to support their keto lifestyle. But how effective are Power Keto Gummies in helping users reach their weight loss goals? In this comprehensive review, we will delve into the ingredients, benefits, and potential side effects of Power Keto Gummies to determine their effectiveness.

Ingredients of Power Keto Gummies

Power Keto Gummies are made with a blend of natural ingredients that are commonly used in ketogenic supplements. These ingredients include exogenous ketones like beta-hydroxybutyrate (BHB), which can help support the body’s ketosis process. Other key ingredients in Power Keto Gummies may include MCT oil, green tea extract, and electrolytes to provide energy and hydration during the ketogenic diet.

One of the main benefits of Power Keto Gummies is their ability to help the body enter ketosis faster. Ketosis is a metabolic state where the body burns fat for energy instead of carbohydrates, leading to weight loss. By providing the body with exogenous ketones, Power Keto Gummies can help jumpstart the ketosis process, making it easier for users to achieve their weight loss goals.

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Benefits of Power Keto Gummies

Power Keto Gummies offer several benefits for individuals following a ketogenic diet. One of the primary benefits is increased energy levels due to the presence of exogenous ketones and MCT oil. These ingredients provide a quick source of energy for the body, making it easier to stay active and maintain a consistent workout routine.

Another benefit of Power Keto Gummies is appetite suppression. Following a ketogenic diet can sometimes lead to cravings and hunger pangs, which can make it challenging to stick to the diet. Power Keto Gummies may help curb cravings and reduce appetite, making it easier for users to maintain a caloric deficit and lose weight.

Potential Side Effects of Power Keto Gummies

While Power Keto Gummies are generally considered safe for most users, there are potential side effects that individuals should be aware of. Some users may experience digestive issues like diarrhea, bloating, or stomach discomfort when first starting with Power Keto Gummies. These side effects are usually temporary and can be minimized by starting with a lower dose and gradually increasing it over time.

It is also essential to note that individual results may vary when using Power Keto Gummies. While some users may experience significant weight loss and improved energy levels, others may not see the same results. It is crucial to combine Power Keto Gummies with a healthy diet and regular exercise routine for the best outcomes.

Conclusion

Overall, Power Keto Gummies can be an effective supplement for individuals looking to support their ketogenic lifestyle and achieve their weight loss goals. With a blend of natural ingredients and potential benefits like increased energy levels and appetite suppression, Power Keto Gummies can help users stay on track with their fitness journey. However, it is essential to consult with a healthcare professional before starting any new supplement regimen to ensure it is safe and appropriate for individual needs.

Give Power Keto Gummies a try today and experience the benefits of this popular weight loss supplement!

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