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Eli Lilly is set to unveil pivotal Phase 3 trial results for orforglipron in Q3 2025—a potential game-changer in obesity treatment. This oral GLP-1 drug aims to rival injectable giants like Wegovy by offering effective weight loss without needles. Early diabetes trials showed a 7.9% body weight reduction, raising hopes for similar success in overweight and obese patients. If approved, orforglipron could revolutionize access to weight-loss therapies with its convenience and lower cost. Investors, healthcare pros, and patients alike are watching closely as Lilly targets FDA approval by mid-2026. Stay tuned for what could be a landmark moment in the $100B obesity drug market! Like and share this video to spread the news! #Orforglipron #EliLilly #WeightLoss #ObesityTreatment #GLP1 #PharmaNews #Investing OUTLINE: 00:00:00 Orforglipron: The Oral Weight Loss Pill to Watch

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Thirteen percent of U.S. adults have tried GLP-1 weight loss drugs like Ozempic and Mounjaro -- they are incredibly popular. For some patients, it's the jumpstart they need to a healthier way of life. Mercy Medical Center's Dr. Jessica Cutler puts some patients on the medication to lose weight in order for insurance to cover bariatric surgery. Subscribe to WBAL on YouTube now for more: http://bit.ly/1oJSRCN Get more Baltimore news: http://www.wbaltv.com Like us: http://facebook.com/wbaltv11 Follow us: https://twitter.com/wbaltv11 Instagram: https://www.instagram.com/wbaltv11/

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**Title**: Beginners Bodybuilding Kaise Start Karein "Bodybuilding shuru karne ka sapna har ek beginner ka hota hai, lekin kahin se start karna thoda challenging lagta hai. Aaj ki video mein hum aapko ek perfect plan dene wale hain beginners ke liye, aur popular bodybuilders ki tips bhi share karenge!" --- **Segment 1: Pehla Kadam - Apne Goals Define Karein** "Sabse pehle, aapko apne goals set karne hain. Kya aap muscle gain karna chahte hain? Ya fat loss? Ye clear karna zaroori hai, kyunki aapki diet aur workout routine usi par depend karegi." --- **Segment 2: Gym Join Karein ya Home Workout?** "Agar gym join kar rahe hain, toh ensure karein ki gym mein basic equipment ho jaise dumbbells, barbells, aur machines. Agar aap ghar pe shuru karna chahte hain, toh resistance bands aur adjustable dumbbells le aayen." --- **Segment 3: Diet ka Mahatva** "Bodybuilding ke liye diet kaafi important hai. Popular bodybuilder *Jay Cutler* kehte hain, '70% bodybuilding aapki diet par depend karti hai.' Aapko ek balanced diet follow karni hogi jo protein, carbs, aur fats mein rich ho. - Protein ke liye: Chicken, eggs, paneer, fish. - Carbs ke liye: Brown rice, oats, sweet potato. - Fats ke liye: Nuts, seeds, olive oil." --- **Segment 4: Workout Routine for Beginners** "Week mein 3-4 din ka workout plan banaayein. Shuru mein aapko compound exercises pe focus karna chahiye: 1. Squats (legs ke liye). 2. Bench Press (chest ke liye). 3. Deadlifts (back ke liye). 4. Overhead Press (shoulders ke liye)." *Arnold Schwarzenegger* kehte hain, 'Focus on basic lifts to build a solid foundation.' --- **Segment 5: Rest aur Recovery ka Dhyan Rakhein** "Muscle growth rest ke waqt hoti hai, workout ke waqt nahi. Week mein 1-2 din ka rest lena zaroori hai. Proper sleep (7-8 ghante) aur hydration maintain karein." --- **Segment 6: Supplements Zaroori Hain?** "Supplements beginners ke liye zaroori nahi hote, lekin agar aapki diet se protein complete nahi ho raha hai, toh aap whey protein le sakte hain. Lekin, supplements lene se pehle apne dietician ya trainer se zaroor consult karein." --- **Segment 7: Motivation aur Consistency** "*Ronnie Coleman* kehte hain, 'Everybody wants to be a bodybuilder, but nobody wants to lift heavy weights.' Bodybuilding ek slow process hai. Consistent rahna sabse important hai." --- "Toh doston, agar aap yeh steps follow karte hain, toh ek strong aur healthy physique banana possible hai. Agar aapko yeh video pasand aayi ho, toh like karein, aur naye tips ke liye channel ko subscribe karein. Milte hain agle episode mein hai **Popular Bodybuilders ki Rai:** 1. **Arnold Schwarzenegger:** "Basics pe focus karein aur apne form ko hamesha perfect rakhein." 2. **Ronnie Coleman:** "Patience aur discipline kaafi zaroori hai." 3. **Dorian Yates:** "Overtraining se bachein aur apne body ke signals ko samajhein." 4. **Jay Cutler:** "Diet sabse bada game changer hota hai. Ispar dhyan dein." __________________________________________ music credit : Music track: Storm by Aylex Source: https://freetouse.com/... music credit : music track : AShamaluevMusic ____________________________________________ Bodybuilding guide | ek aise comprehensive manual ka kaam karta hai jo fitness aur strength building ke shaukeen logon ko unki fitness journey mein madad karta hai. Is guide mein aapko workout routines, diet plans, supplement recommendations aur recovery techniques ka detailed overview milta hai. Yeh beginners ke liye basic guidelines se lekar advanced lifters ke liye specialized tips tak, har level ke bodybuilders ke liye useful hoti hai. Proper form, muscle targeting exercises, aur consistency par focus karke yeh guide aapko apne fitness goals achieve karne mein help karegi. Saath hi, motivation aur discipline banaye rakhne ke liye expert advice aur inspirational stories bhi share ki jaati hain. ### Script: Beginners Bodybuilding Ke Liye Guide

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In this 1-day meal plan, healthy meals and snacks combine for a delicious day of eating to help lower cholesterol. You'll find tasty foods like oatmeal, nuts, beans and plenty of fruits and veggies. Subscribe to Eating Well: http://www.youtube.com/subscription_center?add_user=eatingwell Official Website: http://www.eatingwell.com/ Facebook: https://www.facebook.com/EatingWell Twitter: https://twitter.com/eatingwell Pinterest: http://pinterest.com/eatingwell/

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Semaglutide is a medication that has gained popularity in recent years for its potential to aid in weight loss. Originally developed for the treatment of type 2 diabetes, researchers discovered that semaglutide can also help individuals lose weight when taken in higher doses. This breakthrough has sparked interest among many individuals who are struggling to achieve their weight loss goals through diet and exercise alone.

How Semaglutide Works for Weight Loss

Semaglutide works by mimicking the effects of a hormone called glucagon-like peptide-1 (GLP-1), which is naturally produced in the body. GLP-1 helps regulate appetite, food intake, and blood sugar levels. By activating GLP-1 receptors in the brain, semaglutide can help reduce feelings of hunger and increase feelings of fullness, leading to a decrease in calorie intake and ultimately, weight loss.

In addition to its effects on appetite regulation, semaglutide also slows down the rate at which the stomach empties, which can further contribute to feelings of fullness and reduced food intake. This combination of effects makes semaglutide a promising option for individuals looking to lose weight and maintain their results long-term.

It is important to note that semaglutide should be used as part of a comprehensive weight loss program that includes healthy eating, regular physical activity, and behavior modifications. While semaglutide can aid in weight loss, it is not a magic pill and should not be seen as a replacement for a healthy lifestyle.

Consulting with a Healthcare Provider

Before starting semaglutide for weight loss, it is crucial to consult with a healthcare provider to determine if it is the right option for you. Your doctor will assess your overall health, medical history, and weight loss goals to determine if semaglutide is a safe and appropriate treatment for you. They can also provide guidance on how to use the medication effectively and monitor your progress throughout your weight loss journey.

It is essential to follow your healthcare provider’s recommendations for taking semaglutide and attend regular follow-up appointments to track your progress and address any concerns or side effects that may arise. By working closely with your healthcare team, you can maximize the benefits of semaglutide and achieve your weight loss goals safely and effectively.

Remember that individual results may vary, and the effectiveness of semaglutide for weight loss can depend on various factors, such as adherence to treatment, lifestyle habits, and underlying health conditions. It is essential to be patient and consistent with your weight loss efforts and seek support from healthcare professionals and loved ones as needed.

Accessing Semaglutide Online Safely

With the rise of online pharmacies and telemedicine services, accessing semaglutide for weight loss has become more convenient for many individuals. However, it is crucial to ensure that you are obtaining the medication from a reputable and licensed provider to avoid counterfeit products or potential health risks. Here are some tips for safely accessing semaglutide online:

1. Research the online pharmacy: Before making a purchase, research the online pharmacy to verify its legitimacy and reputation. Look for customer reviews, accreditation, and contact information to ensure that the pharmacy is reliable and trustworthy.

2. Consult with a healthcare provider: It is recommended to consult with a healthcare provider before purchasing semaglutide online to ensure that it is the right option for you. Your doctor can provide guidance on dosing, administration, and monitoring while using the medication for weight loss.

3. Check for prescription requirements: Ensure that the online pharmacy requires a valid prescription for semaglutide before making a purchase. Avoid websites that offer the medication without a prescription, as this is illegal and potentially dangerous.

Monitoring and Managing Side Effects

Like any medication, semaglutide can cause side effects in some individuals, which may include nausea, diarrhea, vomiting, and constipation. These side effects are typically mild to moderate in severity and tend to improve over time as your body adjusts to the medication. However, if you experience persistent or severe side effects, it is essential to contact your healthcare provider for further guidance.

Your healthcare provider can help you manage side effects by adjusting the dose of semaglutide, addressing any underlying causes, or prescribing additional medications to alleviate symptoms. It is crucial to report any side effects you experience while taking semaglutide to ensure that you are receiving the appropriate support and care throughout your weight loss journey.

In some cases, severe side effects such as pancreatitis or allergic reactions may occur while taking semaglutide. If you experience symptoms such as severe abdominal pain, vomiting, or difficulty breathing, seek immediate medical attention and discontinue the medication until further evaluation by a healthcare provider.

FAQ

1. Is semaglutide approved for weight loss?

Yes, semaglutide is approved by the Food and Drug Administration (FDA) for chronic weight management in adults with obesity or overweight who have at least one weight-related comorbidity.

2. How long does it take to see results with semaglutide for weight loss?

Individual results may vary, but many people start to see weight loss results within a few weeks to months of starting treatment with semaglutide. Consistent use of the medication, along with healthy lifestyle habits, can help optimize weight loss outcomes over time.

3. Can I take semaglutide for weight loss if I have diabetes?

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Semaglutide is also approved for the treatment of type 2 diabetes at lower doses. If you have diabetes and are interested in using semaglutide for weight loss, consult with your healthcare provider to determine the appropriate dose and treatment plan for your individual needs.

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Metformin is the first-line medication for type 2 diabetes in over 80 percent of global endocrinology guidelines. Evidence: International Diabetes Federation and American Diabetes Association both recommend it as first choice for new diagnoses. About 60 percent of people who take metformin experience weight loss, averaging 3.5 to 4 kilograms (around 8 pounds) per year. Evidence: Multiple meta-analyses (e.g., Diabetes Obes Metab, 2018) show this effect in both diabetics and people with prediabetes or PCOS. Metformin is linked to a lower risk of certain cancers, especially in people with diabetes. Evidence: Studies suggest a 10–40 percent reduction in risk for some cancers (like colon, breast, prostate), but evidence is mixed and not yet conclusive for non-diabetics. Metformin acts mainly by reducing glucose production in the liver (gluconeogenesis), activating the AMPK pathway. AMPK is a central energy sensor, signaling the body to burn fat and save energy. This is a well-documented, universal mechanism in all users. Metformin increases fat burning and improves insulin sensitivity, making it effective for both weight loss and improving blood sugar control. Evidence: Consistent findings in both clinical trials and real-world practice. More than 30 percent of metformin users experience mild gastrointestinal side effects (nausea, bloating, diarrhea), but only about 5 percent stop due to these effects. Evidence: Meta-analyses, e.g., in Diabetes Care, confirm these percentages. Long-term metformin use causes vitamin B12 deficiency in about 5–10 percent of users. Recommendation: Regular B12 monitoring every 2–3 years if on long-term therapy. Supplementation can fully correct the deficiency. Metformin is not recommended for people with severe kidney, liver, or heart failure due to the risk of lactic acidosis (extremely rare—much less than 1 percent if kidneys are normal). Metformin may extend lifespan in animals by about 10 percent. Evidence: Animal studies show this reliably. The TAME trial (for humans) is ongoing, with results expected in 2026. Metformin is frequently used “off-label” in people without diabetes (e.g., prediabetes, PCOS), but current guidelines do not recommend it for weight loss in healthy people due to limited long-term safety data in this group. Disclaimer: This information is provided for general knowledge and educational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always consult with your doctor for any questions or concerns you may have about your health.