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GLP-1 Medications: High Drug Prices, Compounded Risks, and New Frontiers in Obesity & Addiction Treatment In this episode of Downsized News, hosts Laraine and Christopher Durham discuss recent developments in the world of GLP-1 medications and their implications for weight loss and overall health. They begin by covering former President Donald Trump's remarks on the high cost of GLP-1 drugs like Ozempic and Mounjaro, comparing prices between London and New York. The couple also offers their insights on the complexities of the U.S. healthcare system and its price-setting mechanisms. The episode then moves on to discuss Robert F. Kennedy Jr.'s recent confirmation as the head of Health and Human Services and how his initial skepticism of GLP-1 drugs has softened since his new role. He now acknowledges their importance in treating obesity. Another major story is Nova Nordisk's response to Hims and Hers' Super Bowl ad promoting compounded GLP-1 medications as a cheaper alternative to branded drugs. Nova Nordisk warns consumers about the risks associated with compounded medications. The episode also highlights a massive investment by Xplora in France to boost the production of GLP-1s and antibody-drug conjugates, aiming to meet the growing demand for these medications. A survey of over 2,000 doctors offers insights into the medical community's views on GLP-1s, stressing the importance of combining these medications with healthy lifestyle changes for lasting success. Finally, promising new research shows that semaglutide, a GLP-1 medication, may help reduce alcohol cravings and smoking, opening new possibilities for its use beyond weight loss. Semaglutide & Alchohol USe DIsorder Study JAMA: https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2829811 OMADA HEALTH PHYSICIANS SURVEY: https://resourcecenter.omadahealth.com/latest-content/survey-report-primary-care-perspectives-on-glp-1-prescriptions BOOK THE DOWNSIZED AT SEA CRUISE Presented by Mochi Health: https://thedownsized.org/downsized-at-sea-2025/ DOWNSIZED WEBSITE: https://thedownsized.org/ JOIN CLUB DOWNSIZED: https://www.youtube.com/@thedownsized/join DOWNSIZED GLP-1 COMPANION PRODUCT STORE: https://thedownsized.org/downsized-store We use Mochi Health: https://joinmochi.com/. Use Laraine’s code for $40 off: QIYGO8. 00:00 Introduction and Hosts' Weight Loss Journey 01:13 Controversy Over Compounded GLP-1 Medications 04:19 Trump's Take on GLP-1 Drug Prices 09:55 Robert F. Kennedy Jr. as HHS Secretary 13:01 Xplora's Investment in GLP-1 Production 14:11 Doctors' Views on GLP-1 Medications 19:05 Semaglutide's Potential Beyond Weight Loss 21:20 Conclusion and Farewell

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