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Latest GLP-1 Breakthroughs: Kidney Approval, Legal Battles, and Study Insights | Downsized News Join Laraine and Christopher Durham for the latest episode of Downsized News, covering significant updates in the GLP-1 medication world. The episode dives into recent research showing high discontinuation rates for GLP-1 medications like Ozempic, Mounjaro, and Zepbound, revealing surprising reasons behind the drop-offs. It also covers Novo Nordisk's lawsuit against Well Health and FDA actions against compounding pharmacies for failing to meet safety standards. Additionally, a new FDA approval for Ozempic as a treatment for chronic kidney disease adds another layer of interest. Other topics include a recent poll on public opinion regarding GLP-1 medications, a new drug DD01 aimed at protecting liver health, and a study debunking the link between GLP-1s and thyroid cancer. Finally, innovative research from Helix aims to personalize GLP-1 treatments using genetic data and patient health records. Packed with insights, tips, and the latest developments, this episode is a must-watch for anyone navigating life with the disease of obesity. Be sure to like, subscribe, and join their community for more updates and live discussions every Wednesday. 00:00 Introduction and Overview 01:44 Legal Battles: Novo Nordisk vs. Well Health 04:33 FDA's Warning to Pro RX 09:47 Public Opinion on GLP-1 Medications 13:12 Ozempic's New Approval for Kidney Disease 15:39 Study on GLP-1 Medication Discontinuation 17:12 Insurance Barriers and Weight Management 18:50 Personal Experience with GLP-1 Medication 19:14 Stigma and Long-Term Use of GLP-1s 20:51 Support and Counseling for GLP-1 Users 23:01 Cost and Accessibility of GLP-1s 23:52 New Drug Developments for Liver Health 26:10 GLP-1s and Thyroid Cancer Risk 28:39 Genetic Research and Personalized Treatment 32:15 Conclusion and Community Support

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Are you struggling to lose weight despite trying various diet and exercise regimens? If so, you may be considering doctor-prescribed weight loss pills as a possible solution. These medications are designed to help individuals who are obese or overweight shed pounds more effectively than through diet and exercise alone. However, it’s essential to understand that these pills are not a quick fix and should be used in conjunction with lifestyle changes to achieve long-term success. In this article, we will explore some of the most common doctor-prescribed weight loss pills, how they work, and their potential side effects.

Phentermine

Phentermine is one of the most commonly prescribed weight loss medications in the United States. It works as an appetite suppressant, helping to reduce hunger and control cravings. Phentermine is typically recommended for short-term use and should be combined with a healthy diet and exercise program for best results. While phentermine can be effective in jumpstarting weight loss, it can also cause side effects such as increased heart rate, elevated blood pressure, and insomnia. It is crucial to monitor closely while taking this medication and consult with your doctor regularly.

Another potential side effect of phentermine is the risk of dependence or addiction. Due to its stimulant properties, some individuals may develop a tolerance to the drug and experience withdrawal symptoms when they stop taking it. Therefore, phentermine should be used with caution and under the guidance of a healthcare provider.

If you are considering phentermine as a weight loss option, make sure to discuss the potential risks and benefits with your doctor. They can help determine if phentermine is the right choice for your individual needs and provide support throughout your weight loss journey.

Orlistat

Orlistat, sold under the brand name Alli and Xenical, is another common weight loss medication prescribed by doctors. Unlike phentermine, which acts as an appetite suppressant, orlistat works by inhibiting the absorption of fat in the intestine. This means that some of the fat consumed in your diet is not absorbed by the body and is excreted instead.

One of the benefits of orlistat is that it can help individuals lose weight while also improving other health markers, such as cholesterol levels and blood pressure. However, orlistat can cause gastrointestinal side effects such as oily stools, gas, and diarrhea, particularly if you consume high-fat meals while taking the medication. It is essential to follow a low-fat diet while using orlistat to reduce the risk of these side effects.

If you are considering orlistat as a weight loss option, discuss the potential benefits and side effects with your healthcare provider. They can help determine if orlistat is suitable for your individual needs and provide guidance on how to incorporate it into your weight loss plan.

Saxenda

Saxenda is a newer weight loss medication that has gained popularity in recent years. It contains the active ingredient liraglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist. Saxenda works by slowing gastric emptying, reducing appetite, and promoting feelings of fullness after eating.

One of the advantages of Saxenda is its effectiveness in helping individuals lose a significant amount of weight when combined with diet and exercise. Clinical trials have shown that patients using Saxenda can achieve a weight loss of 5-10% of their body weight within a year. However, Saxenda can cause side effects such as nausea, vomiting, and diarrhea, particularly when starting the medication or increasing the dosage.

Before starting Saxenda, consult with your doctor to discuss the potential benefits and risks. They can help determine if Saxenda is the right choice for you and provide guidance on how to use the medication safely and effectively.

Contrave

Contrave is a prescription weight loss medication that combines two active ingredients: bupropion and naltrexone. Bupropion is an antidepressant that can help reduce cravings and control appetite, while naltrexone is used to treat addiction but also has weight loss properties. Contrave works by targeting the brain’s hunger center and reward system to help individuals eat less and feel satisfied with smaller portions.

One of the advantages of Contrave is its ability to address both physical and emotional components of weight loss. By targeting cravings and emotional eating, Contrave can help individuals make healthier food choices and stick to their diet plan. However, Contrave can cause side effects such as nausea, constipation, and headache, particularly when starting the medication.

If you are considering Contrave as a weight loss option, consult with your doctor to discuss the potential benefits and risks. They can help determine if Contrave is suitable for your individual needs and provide guidance on how to use the medication safely.

Belviq

Belviq is a weight loss medication that works by targeting serotonin receptors in the brain to help individuals feel full and satisfied after eating. Belviq is generally well-tolerated and can help individuals lose weight when combined with a healthy diet and exercise program. However, Belviq can cause side effects such as headaches, dizziness, and fatigue, particularly when starting the medication or increasing the dosage.Combating Obesity Combining Lifestyle Weight Loss Drugs The Medicine Box Cnbc Tv18

One of the potential risks of Belviq is its association with an increased risk of cancer. In 2020, the FDA requested the withdrawal of Belviq from the market due to safety concerns. If you were taking Belviq before the withdrawal, consult with your doctor to discuss alternative weight loss options.

Before starting Belviq or any weight loss medication, talk to your healthcare provider to weigh the potential benefits and risks. They can help determine if Belviq is the right choice for your weight loss journey and provide guidance on how to use the medication safely and effectively.

Summary and FAQ

Overall, doctor-prescribed weight loss pills can be a helpful tool for individuals struggling to lose weight through diet and exercise alone. By working with a healthcare provider, you can determine which weight loss medication may be suitable for your individual needs and goals. It’s essential to understand the potential risks and side effects of these medications and use them as part of a comprehensive weight loss plan that includes lifestyle changes.

Here are some frequently asked questions about doctor-prescribed weight loss pills:

1. Are weight loss pills safe to use?

While doctor-prescribed weight loss pills can be effective in aiding weight loss, they can also cause side effects and risks. It’s essential to work closely with a healthcare provider to monitor your progress and ensure the safe use of these medications.

2. Can I take weight loss pills without changing my diet and exercise habits?

Weight loss pills are most effective when used in conjunction with a healthy diet and regular exercise. These medications are not a substitute for lifestyle changes but can help support your weight loss efforts when used as part of a comprehensive plan.

3. How long can I take weight loss pills?

The duration of weight loss pill use will depend on the specific medication and your individual weight loss goals. Some medications are recommended for short-term use, while others may be used long term under the supervision of a healthcare provider.

4. What should I do if I experience side effects while taking weight loss pills?

If you experience side effects while taking weight loss pills, contact your healthcare provider immediately. They can help determine the cause of the side effects and provide guidance on how to manage them effectively.

5. Are weight loss pills suitable for everyone?

Weight loss pills may not be suitable for everyone, particularly individuals with certain medical conditions or who are pregnant or breastfeeding. Consult with your doctor before starting any weight loss medication to ensure it is safe and appropriate for your individual circumstances.

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What are some common side effects of medications like Ozempic and Wegovy? From the front lines of healthcare, we explore adverse effects of these medications based on real-world visits to the emergency department. Learn about common side effects such as nausea, dehydration, and muscle wasting, as well as lesser-known risks like starvation ketosis and mood changes. Chapters 0:00 - Introduction to & GLP-1 RAs 0:48 - Nausea and Vomiting as Side Effects 1:52 - Dehydration Leading to Kidney Injury 3:11 - GLP-1 RAs & Starvation Ketosis 4:16 - Muscle Wasting on GLP-1 RAs 5:08 - Depression and Mood Changes 5:39 - Honorable Mention: Gastroparesis Video on Muscle Wasting & GLP-1 Receptor Agonists: https://youtu.be/Po2gC3zG0C8 Spotify Channel: https://podcasters.spotify.com/pod/show/sterlingmdphd/ Social & Website: Instagram - https://www.instagram.com/sterlingmdphd Newsletter - http://eepurl.com/hQpdqT Apple Podcasts: https://apple.co/3y438C9 References & Show Notes: http://www.nicksterling.com/ This content is not medical advice, is for general information purposes only and does not constitute the practice of medicine or any other healthcare professional services. No doctor-patient relationship is formed. This content is not a substitute for medical evaluation or treatment and does not take precedence over information provided to you by your healthcare provider or official public health sources. Please visit http://nicksterling.com/terms for full Terms of Use.

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