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In this thought-provoking episode, we’re joined by Dr. Mary Pardee, ND, IFMCP, to dive deep into the science behind GLP-1 drugs like Ozempic and their role in weight loss and metabolic health. Together, we explore the latest research on the risks and benefits of these medications, sharing personal weight loss journeys and body image stories. Join Our Women's Accountability Group https://getstepitup.life/accountabilitygroup2025 📌 Follow Helene & Penelope: Instagram: @stepitups Threads: @stepitups TikTok: @stepituppp YouTube: Step It Up Website: Step It Up Substack: Step It Up 📌 Follow Dr. Mary Pardee: Instagram: @dr.marypardee YouTube: Dr. Mary Pardee 📚 Referenced Research & Resources: FDA Safety Communication on Ozempic FDA Drug Label Information JAMA Network Study on GLP-1 Drugs MedlinePlus Ozempic Side Effects ScienceDirect on GLP-1 Drugs The Lancet on GLP-1 Agonists EMA GLP-1 Agonists PMC Article on Pancreatitis NEJM SELECT Trial BMJ on GLP-1 Agonists Endocrine Society MedPage Today European Medicines Agency (EMA) ScienceDirect The Lancet American Diabetes Association (ADA) Clinical Diabetes and Endocrinology Journal Cochrane Library STEP Trial and Cardiovascular Risks SELECT Trial Data PMC Articles FDA Adverse Event Reporting System MHRA Yellow Card System Pancreatitis and Gallbladder Disease Data PubMed (National Library of Medicine) Mayo Clinic Ozempic Overview American Family Physician (AAFP) Yale on Obesity Drugs Cleveland Clinic MedlinePlus Obesity Action Coalition ClinicalTrials.gov Bmi Doctors on Semaglutide and Blood Clots FDA Access Data Elsevier Health MinuteMD Link to Study (Gallagher et al. 2000) Link to Study (Weiss et al. 2017) Link to Study (Heitmann & Garby 2002) Link to Study (Zeng et al. 2023) Disclaimer: Helene and I are not medical doctors and do not promote or endorse the use of Ozempic or any weight loss drugs. Our mission is to guide women toward natural, sustainable health solutions. #stepitup #weightlossdrugs #ozempic #health #podcast

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In case you ever need to lose fat with no gym access or even understand better how the gym works. There are some glitches and bugs with the gym so I figured this could help some people, I'll also make an informed video on other stats. Music: Art of Silence - by Uniq" is under a Creative Commons license (Creative Commons – International Recognition 4.0 – CC BY 4.0

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Learn More at: http://RaspberryKetoneLiquidDrops.com The good news is that science makes a new breakthrough everyday in coming up with solutions for weight loss. Supposing a discovery for a way of losing weight shows that it works scientifically as opposed to irresponsible claims. Raspberry ketone liquid drops could just be that discovery. The benefits of Raspberry Ketone liquid drops have been proven in laboratory tests. Many people looking for weight loss solutions may have heard about it, but wondered what Raspberry Ketone is all about. The answer to this is that it is a component found in raspberries, which gives them their distinct aroma. Scientists had already figured out that substances containing components similar to those of Raspberry Ketone caused fats to break down. They then performed tests to find out if Raspberry Ketone would perform the same. In experiments carried out on rats, the scientists found out that when fed diets with high fat, rats that were also fed with Raspberry Ketone has less liver and abdominal fat. Further studies proved that Raspberry Ketone made the body produce more amounts of adiponectone, a protein that helps break down stored fat and regulate metabolism. This means that Raspberry Ketone alters fat and lipid metabolism, improving and even preventing fatty liver and obesity. Hence, taking Raspberry Ketone together with sensible exercise and eating can make significant progress in weight loss. Prior to purchasing Raspberry Ketone liquid drops, it is advisable for some seeking weigh loss to first read the label. They should ensure that the supplement they buy is manufactured using Raspberry Ketone that is 100% natural. This is because some brands are known to apply a synthetic substitute when manufacturing the drops. They should also be on the lookout for additives, since some brands have fillers or additives. Other brands combine Raspberry Ketone with some extracts that can lead to shakiness or nervousness similar to those experienced when one takes too much caffeine. Raspberry Ketone liquid drops do have a few side effects that someone seeking weight loss can comfortably cope with. Since they regulate the release of norepinephrine, it leads to an increase in body temperature that is capable of causing a temporary increase in rates of metabolism. In addition, the norepinephrine can also raise the heart beat rate and blood pressure in small margins. Therefore, people suffering from heart condition, diabetes, asthma and high blood pressure are advised to consult a doctor prior to taking Raspberry Ketone.

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Are you taking Metformin and wondering which drinks you should avoid? In this video, we reveal the top 7 drinks to steer clear of while on Metformin, highlighting their impact on Metformin's effectiveness and potential side effects. Learn about the key Metformin side effects and how certain beverages can interfere with its pharmacology and your overall health. We’ll discuss the effects of Metformin on weight loss, its mechanism in diabetes management, and its role in anti-aging and PCOS treatment. Discover how drinks can exacerbate Metformin side effects, including vitamin deficiencies and interactions with other medications like Glimepiride. We’ll also explore healthier alternatives that complement your Metformin regimen, ensuring you manage your diabetes effectively and minimize side effects. Whether you’re using Metformin 500 mg, 850 mg, or 1000 mg, understanding these interactions is crucial for optimizing your treatment. Watch now to get informed and make better choices for your health! Alternatives: We’ll suggest healthier drink options to keep your Metformin treatment on track.

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Polycystic Ovary Syndrome (PCOS) affects millions of women worldwide, leading to distressing symptoms and potential health complications. While various treatment options have been explored, a recent breakthrough has emerged in GLP-1 agonists, offering new hope and possibilities for managing this complex condition. In this podcast, we'll talk about what PCOS is, common symptoms of PCOS, current treatments available for PCOS, including lifestyle changes and medications, and the role of GLP-1 agonists in this condition. What is PCOS? PCOS is a hormonal imbalance that affects people with ovaries. It affects different parts of the body, including the reproductive system, metabolism, and the skin. People with PCOS usually have high levels of "male hormones", specifically androgens. Some examples of androgens are testosterone, DHEAS, and DHT. People with PCOS also have high levels of insulin. When there are high levels of insulin, it can cause insulin resistance. In this situation, the cells in the body ignore insulin. When this happens, blood sugar levels are high, which can lead to prediabetes and type 2 diabetes. People with PCOS may also have irregular periods. This is also due to high levels of androgens in the body. Unfortunately, because of this, PCOS is one of the most common causes of infertility. It's also associated with sleep apnea, obesity, acne, high blood pressure, and high cholesterol. It can also increase the risk of depression and anxiety. What are the symptoms of PCOS? Some people may have one or two symptoms. Common symptoms include irregular periods (e.g., no period, missed period, or very heavy periods) and cysts on one or both ovaries. Others may experience fertility problems and obesity. At the same time, others can experience skin problems such as increased hair growth on the face, chest, stomach, and upper thighs (hirsutism), acne or oily skin, or patches of thick, dark skin on the neck, armpits, or genitals (acanthosis). What are common PCOS treatments? Lifestyle changes should focus on nutrition (healthy balanced diet) and exercise. This is because weight loss can lower your androgen levels, improving PCOS symptoms and lowering your risk of heart disease and diabetes. Weight loss can also help regulate your menstrual cycle, increasing ovulation and pregnancy rates. Medication options for PCOS include hormonal birth control to help regulate periods and improve acne. It may also include medications that lower or block androgen levels, such as spironolactone, flutamide, and finasteride. These medications help with acne and excess hair growth. Metformin should be used for women and adolescent girls with PCOS and type 2 diabetes. Metformin helps lower blood sugar levels to help insulin resistance due to PCOS. It may also help with irregular periods. Some people may require medications that help with fertility. Some examples include clomiphene and letrozole. These medications help stimulate ovulation, which increases your chance of getting pregnant. The role of GLP-1 agonists for PCOS GLP-1 (Glucagon-Like Peptide-1) agonists like semaglutide are a class of medications primarily used to manage diabetes. However, recent research has uncovered their potential in treating PCOS. GLP-1 is a hormone that stimulates insulin secretion and inhibits glucagon production, helping to regulate blood sugar levels. In the context of PCOS, these agonists offer several benefits: 1. Managing Insulin Resistance: Insulin resistance is a common feature of PCOS, leading to elevated insulin levels in the bloodstream. GLP-1 agonists enhance insulin sensitivity, assisting the body in utilizing insulin effectively. Doing so helps regulate blood sugar levels and reduce the risk of type 2 diabetes in women with PCOS. 2. Weight Management: Many women with PCOS struggle with obesity, exacerbating the syndrome's symptoms. GLP-1 agonists can promote weight loss by increasing feelings of fullness, reducing appetite, and slowing down gastric emptying. This weight loss can lead to improved hormonal balance and reduced severity of PCOS symptoms. 3. Restoring Menstrual Regularity: One of the hallmark signs of PCOS is irregular menstrual cycles. GLP-1 agonists have been found to restore menstrual regularity by addressing the underlying insulin resistance and hormonal imbalances. This regularity is important for improving fertility and overall reproductive health. 4. Reducing Androgen Levels: Elevated levels of androgens in women with PCOS contribute to symptoms like acne and excessive hair growth. GLP-1 agonists help lower androgen levels, alleviating these distressing symptoms and improving the quality of life for individuals affected by PCOS. Thanks again for listening to The Peptide Podcast, we love having you as part of our community. If you love this podcast, please share it with your friends and family on social media, and have a happy, healthy...