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This video is a complete drug review of tirzepatide (Zepbound), the latest FDA-approved injectable weight loss medication for obese and overweight individuals. Tirzepatide is given as a once a week injection under the skin. It is the first “dual-agonist” weight loss drug because it mimics two incretin hormones in the body, GLP-1 and GIP. In a large clinical study involving non-diabetic obese patients, tirzepatide at a dose of 15 mg weekly demonstrated an 18% reduction in weight compared to placebo after 72 weeks of treatment. The dose must be slowly titrated upward to reach the target dose to reduce the incidence of gastrointestinal adverse effects. The cost of Zepbound is $1060 for a one month’s supply. Patients who are commercially insured may be eligible for a discounted price.

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Novo Nordisk A/S named its head of international operations as chief executive officer after slumping weight-loss drug sales led to a profit warning that wiped $93 billion off its market value. The Danish drugmaker promoted Maziar Mike Doustdar, who has spent more than three decades with the company, to the top spot. The surprise choice disappointed investors who were hoping for a high-profile outsider to lead a fresh challenge to Eli Lilly & Co., which has been pulling ahead of Novo in the obesity market. Bloomberg's Michael Shah reports. The appointment came shortly after Novo slashed its financial forecast, predicting this year’s sales will grow 8% to 14%, while operating profit expands 10% to 16%, based on constant exchange rates. That compares with its previous growth forecasts of as much as 21% and 24%, respectively.   Shares of Novo plunged as much as 30% in Copenhagen, the biggest intraday drop on record.  Doustdar said he plans to “increase the sense of urgency and execute differently,” and his top priorities will be advancing Novo’s drug pipeline, innovation and investing to deliver growth.  The new CEO, who takes over on Aug. 7, also said on a call with journalists that he’s planning to review the company’s cost base, without citing specific targets for cuts. That indicates Novo is preparing for a period of slower growth after the initial surge of demand for its blockbuster obesity drug, Wegovy, that briefly made the company Europe’s biggest by market value.  “Analysts will start to question both near-term and longer-term obesity expectations that have ballooned out of control,” said Jared Holz, a health-care strategist at Mizuho Securities USA LLC.  Holz and other analysts questioned whether an insider will be able to restore investor confidence. Given the company’s recent struggles, “we are surprised by the choice of an internal candidate,” said Benjamin Jackson, an analyst at Jefferies LLC. Novo announced the ouster of former CEO Lars Fruergaard Jorgensen in May, seeking a reset following a string of setbacks. Though Doustdar, 54, is an insider at Novo, he brings a more international background than some of the company’s previous leaders. He’s Iranian-born, with Austrian citizenship.  Novo’s past CEOs have all been Danish and were intertwined with the company prior to taking over. Two were sons-in-law of previous company leaders. After enjoying an early advantage as a first mover in the obesity drug market, Novo is struggling with competition as Lilly’s Zepbound wins market share over Wegovy. Lilly also appears better positioned to dominate for years to come. It has an easy-to-take weight-loss pill that will come to market as soon as early 2026 and it’s studying a shot that’s shown signs of being as effective as bariatric weight-loss surgery. Novo’s own next-generation candidate, CagriSema, has fallen short of both the company’s and analysts’ hopes in clinical trials.  The company is also facing competition from compounding pharmacies that are allowed to make copies of drugs when they are in short supply. Novo estimates about 1 million patients in the US are using compounders in the US market, Chief Financial Officer Karsten Munk Knudsen said on a call. Novo said it will fight compounding in the courts and invest in its own direct-to-patient marketing efforts. Novo has said a new contract with CVS Health Corp. for Wegovy would drive volume from July 1.  The slashed forecast reflects competition for both Wegovy and its sister drug Ozempic for diabetes, the company said. The drugmaker also cited slower than expected market growth for weight-loss drugs.   Novo’s sales climbed 18% in constant currencies in the second quarter, the company said, with operating profit rising 40%. The company will publish complete second-quarter results on Aug. 6. The foundation that controls the company pushed for Jorgensen to go and instated his predecessor, Lars Rebien Sorensen, as an observer on Novo’s supervisory board. Sorensen is set to return as a full board member next year.  -------- Watch Bloomberg Radio LIVE on YouTube Weekdays 7am-6pm ET WATCH HERE: http://bit.ly/3vTiACF Follow us on X: https://twitter.com/BloombergRadio Subscribe to our Podcasts: Bloomberg Daybreak: http://bit.ly/3DWYoAN Bloomberg Surveillance: http://bit.ly/3OPtReI Bloomberg Intelligence: http://bit.ly/3YrBfOi Balance of Power: http://bit.ly/3OO8eLC Bloomberg Businessweek: http://bit.ly/3IPl60i Listen on Apple CarPlay and Android Auto with the Bloomberg Business app: Apple CarPlay: https://apple.co/486mghI Android Auto: https://bit.ly/49benZy Visit our YouTube channels: Bloomberg Podcasts: https://www.youtube.com/bloombergpodcasts Bloomberg Television: https://www.youtube.com/@markets Bloomberg Originals: https://www.youtube.com/bloomberg Quicktake: https://www.youtube.com/@BloombergQuicktake

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My #1 life hack next to carnivore diet. Did you know you do NOT burn fat, you actually breath MOST of it out. Oxygen is another energy system of the body, Respiration is a combustion process, when you add 02 to carbon in your body, they break down through respiration in your mitochondria forming C02, H20, and energy. The C02 you breath out, the H20 you urinate, sweat etc. this is the mass that carries the fat. The carbon is your food. Strength training starts with controlling your breathing. 2x light warm up techniques, 3 rounds of HIIT for activation, fitness, strength training, and fat loss. and 1x warm down session. fat is moved through the lymphatic system, carried in lymphfluid, the circulation is vital, then You breath out fat, breathwork is perfect for fat loss, When you're low on fuel, your body breaks down fat to create energy. This process releases heat and fuel to power muscles, and the fat is converted into carbon dioxide and water. Most of it is turned into carbon dioxide, which you exhale through your lungs. The water mixes into your circulation and is lost as urine or sweat Increase your VO2, RBC counts, EPO, and more, There are numerous benefits to breath work, including stimulating HIFs through low oxygen tension. HIFs stimulate the kidneys to produce a hormone known as EPO, which has numerous functions that aid the brain, heart, and other organs. But it also stimulates the bone marrow to produce more RBCs. HIFs also regulate the uptake of iron, and so much more. Help me keep this channel going, Buy me a coffee- https://www.buymeacoffee.com/dclearningtolive Please help me keep this fight against cancer going https://www.givesendgo.com/learningtolive The only dietary enhancer I endorse, and use myself- https://dcfit.cerule.com/ Cerule products, StemEnhance Ultra, PlasmaFlo, and Cyactiv for crypto storage I recommend Ledger https://shop.ledger.com/pages/referral-program?referral_code=H4G04MBHFF4D6 buy and trade crypto https://trade.swyftx.com/register/?ref=davidkemp1 The VPN i use is Nord https://refer-nordvpn.com/vQDoYIoiYPX Why I use Cerule products- https://youtu.be/ri1NWXxgv7k Carnivore clothes, for you and your pets- https://my-store-100dfca.creator-spring.com/ Instagram https://www.instagram.com/dclearningtolive/ Twitter/ X https://x.com/DavidChar1973 Facebook https://www.facebook.com/dclearningtolive 3/11 AFTERMATH: These are personal photos taken in the months after the Earth Quake and Tsunami in Japan, March 2011 https://www.amazon.com/dp/B0C123D9B8 https://www.amazon.com.au/dp/B0C1295Q49 https://www.amazon.com.au/dp/B0C15FVPVW Follow me on Facebook https://www.facebook.com/dclearningtolive/ and Twitter THANK YOU SO VERY MUCH TO ALL MY PATRONS Patrons thank you- https://www.patreon.com/posts/thank-you-so-87820046?utm_medium=clipboard_copy&utm_source=copyLink&utm_campaign=postshare_creator&utm_content=join_link Disclaimer, I am NOT your doctor, nor trainer, I am merely discussing my own experiences, and how I dealt with them. none of this is to be considered medical advice #losefat #fatloss #breathwork #breathworkhealing #weightloss #burnfat #carnivorediet #lowcarbhighfat #hightfat

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🔍 Why the Ketogenic Diet is Effective for Weight Loss Looking for an effective way to shed pounds and transform your health? In this video, we break down the science behind the ketogenic diet and why it’s one of the most popular and effective methods for weight loss. Learn how keto works, what it does to your metabolism, and how you can start your own journey today! 📌 What You’ll Learn: How the ketogenic diet promotes fat-burning and reduces hunger. The role of ketosis and its impact on weight loss. Insider tips for starting and sustaining a successful keto lifestyle. Real-life results and benefits of the keto diet. 👨‍⚕️ Featuring insights from health experts and success stories from real people, this video is your go-to guide for understanding keto and its powerful effects on the body. 💡 Want to learn more about health and weight loss? Subscribe for more science-backed tips and strategies! 🎥 Watch Now and kickstart your keto journey to a healthier, happier you! #KetoDiet #WeightLoss #KetogenicDiet #HealthyLiving #fatburningtea "This video is not medical advice and was not created by a medical professional. Always consult a qualified healthcare provider for any medical concerns or questions about your health."

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