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Recorded live at the 2025 Atlanta Cardiovascular Symposium, we explore groundbreaking advancements at the intersection of cardiology and metabolic health. Join Dr. Ben Goins from Heart and Vascular Care as we take a deep dive into the emerging role of GLP-1 Agonists—a class of medications transforming the way we manage cardiovascular risk, obesity, diabetes, and more. Discover how these therapies are not only helping patients lose weight but also reducing the risk of major adverse cardiovascular events and improving outcomes in complex, high-risk populations. Whether you're a provider navigating the evolving landscape of cardiometabolic care or a patient advocate seeking to stay informed, this episode offers expert insights into one of today’s most promising therapeutic tools.

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John B. Buse, MD, PhD, reviews the findings from the ELIXA trial with lixisenatide in patients with type 2 diabetes.

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Is Orforglipron the Obesity Weight Loss Breakthrough We've Been Waiting For? Is it better than Rybelsus and Oral Wegovy? If you need assistance in your journey to reach your weight loss goals, book a consultation with me: https://calendly.com/drdanburton/weight-loss-consult Join this channel to get access to perks: https://www.youtube.com/channel/UCnQiofnuXFcloJRoJTsc1FQ/join Download my FREE GLP-1/GIP Medication Information Sheet: http://eepurl.com/gdB2qn Try my fancy dancy Total Daily Energy Expenditure (TDEE) Calculator: https://healthevolved.co/tdee-calculator/ Subscribe to the channel: https://www.youtube.com/@theofficialdrdan?sub_confirmation=1 – I have great news for those who dislike needles or prefer a daily reminder to engage in positive behaviors. There’s a new oral GLP-1 molecule making its way to market called Orforglipron! Currently, Rybelsus is the only oral GLP-1 available, approved for diabetes management up to a dose of 14mg once daily. Rybelsus contains semaglutide, found in Ozempic and Wegovy, but it’s not yet approved for weight management. Orforglipron, on the other hand, is a game-changer. It’s an oral nonpeptide GLP-1 receptor agonist that can be taken without regard to food, drink or other medications. It’s designed to be absorbed through the digestive tract, without needing an absorption enhancer like Rybelsus. This makes it more convenient for daily use. So, how effective is Orforglipron? The Phase 2 RCT trial involved 272 participants with obesity, split into groups receiving either 12mg, 24mg, 36mg, or 48mg of Orforglipron daily, or a placebo. Participants received basic counseling on healthy eating and exercise. The study found that participants, mostly female with an average age of 54, weight of 108.7kg, and BMI of 37.9, saw impressive results. Those on 45mg daily of Orforglipron lost 14.7% of their baseline weight after 36 weeks, and the weight loss trend hadn’t plateaued yet. For reference, this is comparable to results from the OASIS Trial with oral semaglutide at 50mg daily, which led to a 15.1% weight loss after 68 weeks. Safety-wise, the side effects were typical for GLP-1 receptor agonists: nausea, vomiting, diarrhea, and constipation. Nothing out of the ordinary here. Orforglipron is a promising new oral GLP-1 RA that might offer a more convenient and potentially more effective option for weight management. Its smaller molecule size might also mean a cheaper alternative, though time will tell. Thanks for watching and always remember: small tweaks lead to massive peaks! - Dr. Dan – Products I recommend to support your weight-loss journey: ▪️ Managing Constipation: https://amzn.to/4bs0g3h ▪️ Managing Diarrhea: https://amzn.to/3UUjNCm ▪️ Managing Heartburn: https://amzn.to/3Vbfx31 ▪️ Internalized Weight Bias: https://amzn.to/4avCpP3 ▪️ Protein Bars: https://amzn.to/3RiItUr ▪️ Scales and More: https://amzn.to/4bNJDPc ▪️ Supplements: https://amzn.to/44TgobJ ▪️ Activity Trackers I recommend: https://amzn.to/4dOYLOa ▪️ My favorite Books: https://amzn.to/3Kb0VKt 🇺🇸 USA: https://amzn.to/3RC7MSd 🇨🇦 Canada: https://amzn.to/45gq4vg Watch my previous videos about how to fight obesity and about the best medicine for weight loss: ▪️ Rybelsus: Oral Ozempic?: https://www.youtube.com/watch?v=-BWqLrPOuBc&t ▪️ Watch This Before Taking Mounjaro: https://youtu.be/BmkVtGgejhk ▪️ From Ozempic to Mounjaro: https://youtu.be/L9e46iFWwIs ▪️ Muscle Loss with Ozempic, Wegovy & Mounjaro: https://youtu.be/lnEH-v64aG0 ▪️ Managing Nausea from Ozempic, Wegovy and Trulicity!: https://youtu.be/3R1Fwhf02LE ▪️ Ozempic: Stomach Paralysis Update: https://youtu.be/MPyROywaM0g ▪️ Ozempic Paralyzed My Stomach: https://youtu.be/tj9thkkN5aM – Live in Alberta? Come see me at my Pharmacist-led Obesity Clinic at Apothecare Pharmacy - http://apothecarerx.ca – Sign up for my newsletter: http://eepurl.com/gdB2qn – Contact Me: [email protected] – Have questions or need support on your weight-loss journey? Book a consultation with me: https://calendly.com/drdanconsult/he – For more about weight loss via habit mastery, visit https://www.healthevolved.co Join me on social media: ▪️ https://www.facebook.com/theofficialdrdan ▪️ https://www.instagram.com/theofficialdrdan ▪️ http://threads.net/@theofficialdrdan Disclaimer of Medical Liability. HEALTHCARE EVOLUTION INC. DOES NOT PROVIDE MEDICAL ADVICE. The content of this material is for general informational purposes only. The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Reliance on any information provided here is solely at your own risk. Individual medical needs are very different; you should not assume that the information in this document concerning certain courses of treatment or outcomes will apply to you. Rather, you should evaluate your medical condition and make treatment decisions based upon consultation with your physician. #Obesity #Orforglipron #Wegovy

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The ketogenic diet has gained immense popularity in recent years for its ability to help with weight loss, improve mental clarity, and boost energy levels. However, following a strict keto diet can be challenging, especially for those with busy lifestyles. That’s where GNC Keto ACV Gummies come in. These convenient and delicious gummies are designed to support ketosis and provide a range of health benefits.

What are GNC Keto ACV Gummies?

GNC Keto ACV Gummies are a unique blend of ingredients specially formulated to support ketosis. Each gummy contains apple cider vinegar (ACV) along with other key nutrients that help the body enter and maintain a state of ketosis. Ketosis is a metabolic state in which the body burns fat for fuel instead of carbohydrates, leading to weight loss and other health benefits.

These gummies are a convenient and tasty way to support your ketogenic diet. They are easy to take on the go and can be incorporated into your daily routine with ease. Plus, they are free from artificial colors, flavors, and preservatives, making them a healthy choice for anyone following a keto lifestyle.

With GNC Keto ACV Gummies, you can enjoy the benefits of apple cider vinegar and other key nutrients without the hassle of measuring or mixing ingredients. Simply pop a gummy in your mouth and enjoy the delicious taste while supporting your ketosis goals.

How do GNC Keto ACV Gummies work?

GNC Keto ACV Gummies work by providing your body with the nutrients it needs to support ketosis. Apple cider vinegar is a key ingredient in these gummies, known for its ability to help regulate blood sugar levels, improve digestion, and support weight loss. ACV also contains acetic acid, which has been shown to help the body burn fat more efficiently.

In addition to apple cider vinegar, GNC Keto ACV Gummies contain other key nutrients like vitamin B6, vitamin B12, and folic acid. These nutrients help support overall health and well-being while promoting a state of ketosis. By taking these gummies regularly, you can help your body stay in ketosis and reap the benefits of a ketogenic diet.

Whether you’re new to the ketogenic diet or a seasoned veteran, GNC Keto ACV Gummies can help you reach your health and fitness goals. These gummies are a convenient and delicious way to support ketosis and enjoy the benefits of apple cider vinegar and other key nutrients.

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1. Supports Ketosis: GNC Keto ACV Gummies provide your body with the nutrients it needs to stay in ketosis, helping you burn fat for fuel and support weight loss.

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2. Convenient and Tasty: These gummies are easy to take on the go and have a delicious apple cider vinegar flavor that makes it easy to incorporate them into your daily routine.

3. Contains Key Nutrients: In addition to apple cider vinegar, GNC Keto ACV Gummies contain vitamin B6, vitamin B12, and folic acid, which help support overall health and well-being.

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Yogesh Bhateja’s Profile Link: Instagram: https://www.instagram.com/yogeshfitness/ Website: https://yogeshfitness.in/ Gunjanshouts’s Profile Links: Instagram: www.instagram.com/gunjanshouts/ YouTube: www.youtube.com/@UCKRpf_HZfpLwxuIgyeYnsVw IMWOW YouTube: https://www.youtube.com/channel/UCTMag_rgAMjoDCWHYX4V6uA Join I'MWOW Transformation Program, WhatsApp link: https://bit.ly/GSYTwhatsapp Official Website: https://bit.ly/37DtL6B I’MWOW HEALTH PRODUCTS Natural Peanut Butter - https://amzn.to/48ftl18 Night Time Relaxing Tea - https://amzn.to/4ebxvsa Sattu Powder Premix Jeera Flavour- https://amzn.to/4edOwmO Chia Seeds - https://amzn.to/4he2S7D Apple Cider Vinegar - https://amzn.to/4honNEt Dream of a career where you can make a difference? Join IAMWOW Academy's Professional Diploma in Nutrition & Dietetics and start changing lives. - https://imwowacademy.com/ You can watch short clips from our previous podcast on our new YouTube channel, Gunjan Talks Clips. Check it out here: https://www.youtube.com/@UCWXtXfjsvEwm0KRzrWPQ3kg ******************************************************** About Guest & Podcast: Yogesh Bhateja, founder and head trainer of Yogesh Fitness, is a celebrated fitness expert known for his holistic and transformative approach to health. With years of experience, multiple certifications, and a deep passion for fitness, he crafts customized workout and nutrition plans tailored to each client’s goals. In this podcast, we talked about celebrity transformations, workout strategies, diet hacks, supplement safety, and even mental conditioning. Whether you're a beginner taking your first step in fitness or someone struggling to stay consistent, this episode gives you a realistic and science-backed roadmap. From Kapil Sharma’s dramatic transformation, Sonu Sood’s discipline, to Farah Khan’s inspiring journey, Yogesh shares stories, strategies, and myth-busting advice that can change the way you approach health and fitness. ******************************************************** Time Stamps: 00:00 - Teaser and Introduction 05:00 - Kapil Sharma’s Fitness Journey 12:47 - “21-21-21 Day” Approach for Beginners 15:20 - Gym during first “21 Days” 22:15 - Kapil’s Training During Shoots 29:20 - Importance of Good Mental Health for Performance 35:05 - Ideal Approach towards Diet 37:35 - Nutrient-Dense Foods and Balance 39:30 - Authentic Supplements in India 41:10 - Meeting Essential Nutrients Intake 43:24 - Boiled egg vs Omelette 45:10 - Eating Bread Omelette Is Not Beneficial? 46:26 - Baked Potato Easy Recipe 56:00 - Cheat Meal 1:04:00 - Gap between Dinner and Sleep 1:05:00 - People who can't sleep without full stomach 1:09:46 - Intermittent Fasting 1:11:04 - Who should follow intermittent fasting? 1:14:10 - Core Exercise to Reduce Belly Fat 1:17:25 - How Celebrities achieve good quality sleep? 1:20:23 - Ensuring clients get quality sleep 1:23:04 - Ideal Sleep Timing 1:24:52 - Farah Khan’s Transformation with Yogesh 1:28:45 - Motivational Celebrity Transformation 1:32:18 - How To Achieve Aesthetic Physique 1:37:42 - Secret Behind Sonu Sood’s Discipline 1:41:21 - Best approach to achieving extreme fitness 1:46:02 - Ideal Workout Session per week 1:48:14 - Ideal duration for warm-up, workout, and cool-down 1:49:16 - Don’t Start Workout with Cardio 1:50:00 - Ideal workout routine for a complete beginner 1:55:21 - Routine for people in 40s-50s 1:57:21 - Daily Supplements You Can Take 2:02:49 - Celebrities Transformation in Limited Time 2:06:10 - Plant-based protein vs Whey protein 2:08:17 - Secret Behind Shah Rukh Khan’s Fitness 2:09:42 - Myth & Fact Session ******************************************************** If you are looking for a customised diet plan then you can join I'MWOW transformation program in which we provide counselling, personalised diet plan, follow along workout videos, recipes, daily positive affirmations, interesting activities and a lot more. Many people from different parts of the world join this program and achieve their fitness goals easily. You can be a part of it too. - https://bit.ly/GSYTwhatsapp 😊👍 ******************************************************** DISCLAIMER: The content on this channel is for educational and entertainment purposes only. I share my personal experiences and learnings from my weight loss journey, along with knowledge from my INFS Nutrition and Fitness certification. However, this is not medical advice—please consult a healthcare professional before following any recommendations. Diet plans in my transformation program are designed by qualified nutritionists. Any products/brands I recommend are based on personal experience, but results may vary, and their use is your responsibility.

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Mindy Kaling, the talented actress, writer, and producer, has always been known for her wit, humor, and undeniable charm. Over the years, she has conquered Hollywood with her unique sense of style and infectious personality. However, in recent times, Mindy has also made headlines for her incredible weight loss transformation. Fans have been amazed at how she has achieved her weight loss goals and transformed her body without sacrificing her signature sense of self.

Mindy’s Secret to Success

Like many individuals on a weight loss journey, Mindy Kaling understands that there is no one-size-fits-all approach to achieving fitness goals. She has been outspoken about the fact that she tried various methods before finding what worked best for her. From incorporating more physical activity into her daily routine to making healthier food choices, Mindy’s transformation is the result of hard work and dedication.

One key aspect of Mindy’s weight loss success is her commitment to consistency. She understands that real change takes time and that small, sustainable habits can lead to significant results over time. By setting realistic goals and staying accountable to herself, Mindy has been able to stay on track and make progress towards her desired outcome.

Additionally, Mindy has emphasized the importance of finding joy in the process. Despite the challenges that come with changing one’s lifestyle, Mindy has found ways to make her fitness journey enjoyable. Whether it’s trying out new workout classes, experimenting with healthy recipes, or simply finding ways to stay active with friends, Mindy has discovered that staying motivated is easier when you’re having fun.

Mindy’s Balanced Approach

One aspect of Mindy’s weight loss journey that has resonated with fans is her commitment to maintaining balance in her life. She understands that being healthy doesn’t mean depriving yourself or sticking to a strict diet. Mindy believes in moderation and enjoys treating herself to the foods she loves in moderation.

Furthermore, Mindy emphasizes the importance of self-care and self-compassion throughout her transformation. She understands that progress is not always linear and that setbacks are a natural part of the journey. By practicing mindfulness and being kind to herself, Mindy has been able to stay motivated and focused on her goals.

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Another key aspect of Mindy’s balanced approach is her focus on mental well-being. She recognizes that true health and wellness go beyond physical appearance and include mental and emotional wellness. Mindy makes time for activities that nourish her soul, such as meditation, journaling, and spending time with loved ones.

Mindy’s Empowering Message

Throughout her weight loss journey, Mindy Kaling has inspired countless fans with her empowering message of self-love and acceptance. She understands the pressures that society puts on individuals to look a certain way, but she also knows that true beauty comes from within. Mindy encourages her followers to embrace their uniqueness and to prioritize their health and happiness above all else.

Furthermore, Mindy’s transformation serves as a reminder that everyone’s journey is different, and there is no one “right” way to achieve your fitness goals. She encourages others to find what works best for them and to stay true to themselves throughout the process. Mindy’s authenticity and openness about her experiences have made her a role model for those looking to make positive changes in their own lives.

In conclusion, Mindy Kaling’s weight loss transformation is a testament to the power of hard work, dedication, and self-love. By finding what works best for her and staying true to herself, Mindy has achieved her weight loss goals while inspiring others to do the same. Her balanced approach, commitment to consistency, and empowering message have made her a beacon of light in the world of health and wellness. Mindy’s journey serves as a reminder that true transformation comes from within and that anything is possible with the right mindset and determination.

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