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Latest GLP-1 Breakthroughs: Kidney Approval, Legal Battles, and Study Insights | Downsized News Join Laraine and Christopher Durham for the latest episode of Downsized News, covering significant updates in the GLP-1 medication world. The episode dives into recent research showing high discontinuation rates for GLP-1 medications like Ozempic, Mounjaro, and Zepbound, revealing surprising reasons behind the drop-offs. It also covers Novo Nordisk's lawsuit against Well Health and FDA actions against compounding pharmacies for failing to meet safety standards. Additionally, a new FDA approval for Ozempic as a treatment for chronic kidney disease adds another layer of interest. Other topics include a recent poll on public opinion regarding GLP-1 medications, a new drug DD01 aimed at protecting liver health, and a study debunking the link between GLP-1s and thyroid cancer. Finally, innovative research from Helix aims to personalize GLP-1 treatments using genetic data and patient health records. Packed with insights, tips, and the latest developments, this episode is a must-watch for anyone navigating life with the disease of obesity. Be sure to like, subscribe, and join their community for more updates and live discussions every Wednesday. 00:00 Introduction and Overview 01:44 Legal Battles: Novo Nordisk vs. Well Health 04:33 FDA's Warning to Pro RX 09:47 Public Opinion on GLP-1 Medications 13:12 Ozempic's New Approval for Kidney Disease 15:39 Study on GLP-1 Medication Discontinuation 17:12 Insurance Barriers and Weight Management 18:50 Personal Experience with GLP-1 Medication 19:14 Stigma and Long-Term Use of GLP-1s 20:51 Support and Counseling for GLP-1 Users 23:01 Cost and Accessibility of GLP-1s 23:52 New Drug Developments for Liver Health 26:10 GLP-1s and Thyroid Cancer Risk 28:39 Genetic Research and Personalized Treatment 32:15 Conclusion and Community Support
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~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ CLICK HERE for Video INFO! ~~~~~~~~~~~~~~~~~ For future Q&A's, leave your questions in the comments and thumb-up the ones you want answered! This week is just a quick update :) The Q&A starts at around 3:30. More info on how much WATER you should be drinking: http://antishayweightloss.com/faq/#water Carla's H4H team #3 video with water info: http://youtu.be/AuHfhC1eihs Take care! **REMEMBER** "A goal without a plan is just a wish." (and) "If we are facing in the right direction, all we have to do is keep on walking." :) **ME ELSEWHERE** Twitter: http://www.twitter.com/antishay Facebook: http://www.facebook.com/antishay Personal Blog: http://blog.shantimarshalla.com Weight-Loss FAQ's: http://www.antishayweightloss.com/faq Weight-Loss How To: http://www.antishayweightloss.com/howto
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Want to live a longer, healthier life? It all starts with building and maintaining muscle. In this compilation episode of The Model Health Show, top experts like Mark Sisson, Dr. Gabrielle Lyon, and Dr. Andrew Huberman share powerful insights on why muscle matters — from boosting immunity and brain health to improving disease resilience and metabolism. Learn the science behind muscle-building and get practical strategies to do it efficiently. This episode is packed with tips to help you stay strong, functional, and healthy for life. Enjoy! Guest(s): Mark Sisson, Dr. Gabrielle Lyon, Alan Aragon, Dr. Andrew Huberman, JJ Virgin, Mark Bell. Subscribe: https://www.youtube.com/@TheShawnModel?sub_confirmation=1 Watch more videos like this: INSTANTLY Boost Energy, Reduce Fatigue & SLEEP BETTER At Night! | Dr. Andrew Huberman: https://youtu.be/AXkESILHqm4 How To LOSE WEIGHT, Stay Young, & Be Fit Forever | JJ Virgin & Shawn Stevenson: https://youtu.be/avf1e3wt-dM Build Muscle Faster & Have Endless Exercise Motivation | Mark Bell & Shawn Stevenson: https://youtu.be/7oLBY9477ZE Build Muscle & Burn Fat Faster Over 40 with Jay Ferruggia: https://youtu.be/ZbfQeRp95e4 Playlist: https://www.youtube.com/playlist?list=PL3zvw5sD7WKyUHLrE3d9x_fRBnOPxqmM- Timestamps: 00:00 - Introduction 00:43 - How Muscle Helps you Live Longer 07:32 - Why Muscle is the Organ of Longevity 18:43 - Muscle is the Metabolic Engine of the Body 22:40 - How Strength Training Makes You Smarter 28:02 - Focus on Muscle First 35:19 - More Ways to Use Your Muscles for Longevity Shawn Stevenson is the author of the USA Today National bestsellers Eat Smarter and the Eat Smarter Family Cookbook, as well as the international bestselling book Sleep Smarter. He’s also the creator of The Model Health Show, featured as the number #1 health podcast in the U.S. with millions of listener downloads each year. A graduate of the University of Missouri–St. Louis, Shawn studied business, biology, and nutritional science and became the cofounder of Advanced Integrative Health Alliance. Shawn has been featured in Forbes, Fast Company, The New York Times, Muscle & Fitness, Good Morning America, ESPN, and many other major media outlets. Get the Eat Smarter Book here: https://eatsmarterbook.com Start the Fat Loss Code Course here: https://www.thefatlosscode.com Order the Eat Smarter Family Cookbook here: https://eatsmartercookbook.com Let’s Connect... Website: https://themodelhealthshow.com X: https://twitter.com/ShawnModel IG: https://www.instagram.com/shawnmodel/ FB: https://www.facebook.com/TheModelHealthShow
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In this video, "Weight Loss Journey | 9 MONTH UPDATE with Measurements: Weigh In Wednesday | Losing 200lbs" I review my ninth month of my weight loss journey and the tactics I used to be successful losing weight, I share my current measurements, weight updates and pictures, and I also do a side by side comparison of last month to this month to when I started. Then, I wrapped up the video by sharing my October Fitness and Weight Loss intentions!! Wish me luck! ♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡ Wanna jump around? ♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡ 00:00 The beginning 00:44 Best Month Yet 01:01 Reviewing March Goals and Tactics 07:30 Other Reflections and Chit Chat 09:36 Let’s Weigh In 11:34 Progress pic and Video 15:38 Non-Scale Points of Measure 18:22 April Goals and Tactics 20:32 Sharing some thoughts #weightlossjourney #weighinwednesday #aprillauren ♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡ Watch next?♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡ Starting my weight loss journey | Losing 200 lbs: https://youtu.be/99Nh4_-wLv0 Can I walk a mile with 200 lbs to lose?: https://youtu.be/-1V_Mz5Jdvs How did I become Morbidly Obese: https://youtu.be/4yA0EqNqZUM Weigh In Wednesday Play List: https://www.youtube.com/watch?v=99Nh4_-wLv0&list=PLR1pnoP-75xDhQNQKlJiMRHsx1sB8XXIT ♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡ A little about me ♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡ My name is April Lauren and my channel, Wake Up Bright, is where I share the chronicles of my weight loss journey to lose 200 lbs, our adventures and my attempts to make home wherever the Army sends. Essentially, my hope is to wake up a little brighter each day and to do all the little things that ensure I do. Wanna Connect? ♡ Insta: https://www.instagram.com/wakeupbright ♡ Facebook: https://www.facebook.com/loveaprillauren ♡ TikTok: http://www.tiktok.com/@april.lauren ♡ Blog: http://www.wakeupbright.com ♡ Email me: [email protected] (Personal) Wanna work with me? Email: [email protected] ♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡ Common Q's♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡ What I'm wearing?! If it's athetic gear, it is probably fabletics: https://fabletics.fjbu.net/loveaprillauren (otherwise, I'll provide links!) What kind of Camera do I use? Go Pro Hero 7: https://amzn.to/2D66nhf Canon G7xII: https://amzn.to/2S1265O Wanna know more about my gym watch my gym tour: https://youtu.be/5ms3_ZwR7pU. (The description also has links to all equipment) Should you start a YouTube Channel? https://youtu.be/pMDUWWRSRjs Wanna do Yoga with me? https://www.youtube.com/channel/UCSlXMj3JZ8mLJqX_o9hpBcw/ More about my pups? https://www.youtube.com/watch?v=vqTIMpZjwIw DISCLAIMER: Links included in this description might be affiliate links. weight loss journey, weigh in Wednesday, one month weight loss progress, how much weight can I lose in a month, starting my weight loss journey ,losing 200 lbs, plan for success, weight loss, how to lose weight, slow and steady weight loss, how to lose weight the healthy way, mental strength, weight loss motivation, watch me shrink, lose weight with me, fat to fit, how to get fit, how to lose fat, how to lose fat when you are overweight, how to lose weight when you're obese
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Semaglutide, a medication often used for the treatment of type 2 diabetes, has recently gained attention for its potential as a weight loss aid. Health authorities around the world have been evaluating the efficacy and safety of semaglutide for weight loss, with some granting official approval for this new indication. This development has sparked excitement among healthcare providers and patients alike, as obesity continues to be a significant health concern globally.
Regulatory Approval in the United States
In June 2021, the U.S. Food and Drug Administration (FDA) approved semaglutide for chronic weight management in adults with a body mass index (BMI) of 30 kg/m² or greater, or with a BMI of 27 kg/m² or greater in the presence of at least one weight-related comorbidity, such as hypertension or type 2 diabetes. This marked a significant milestone in the treatment of obesity, as there are limited pharmacological options available for long-term weight management.
The FDA’s approval was based on the results of several clinical trials, including the STEP program, which demonstrated the efficacy of semaglutide in promoting weight loss when used in conjunction with diet and exercise. Common side effects of semaglutide include nausea, diarrhea, and constipation, but overall, the medication was well-tolerated in clinical trials.
Healthcare providers in the United States now have an additional tool in their arsenal for managing obesity, a condition that affects millions of Americans and is associated with numerous health risks. Semaglutide offers a novel approach to weight loss by targeting the body’s appetite control system, leading to reduced food intake and ultimately, weight reduction.
European Medicines Agency Evaluation
The European Medicines Agency (EMA) has also been evaluating semaglutide for weight management, although as of [insert date], the medication has not yet received official approval for this indication in the European Union. However, the EMA’s Committee for Medicinal Products for Human Use (CHMP) has recommended granting marketing authorization for semaglutide for weight loss.
The CHMP’s recommendation was based on the positive results of clinical trials, which showed that semaglutide was more effective than placebo in achieving weight loss and improving metabolic parameters. The most common side effects reported with semaglutide were gastrointestinal in nature, similar to the findings in the FDA-approved trials.
If approved by the European Commission, semaglutide could become a valuable treatment option for individuals struggling with obesity in the EU. The availability of semaglutide for weight management would address an unmet need in the region and provide healthcare providers with a new tool for helping patients achieve their weight loss goals.
Global Impact and Future Outlook
Outside of the US and EU, other health authorities are also evaluating semaglutide for weight loss, with the potential for additional approvals in the near future. The global obesity epidemic has prompted a renewed focus on finding effective treatments for weight management, making semaglutide a promising candidate for addressing this public health issue.
As more health authorities approve semaglutide for weight loss, the medication is poised to have a significant impact on the field of obesity medicine. Healthcare providers will have access to a new class of medications that target appetite regulation and weight control, offering patients a much-needed solution for managing their weight and improving their overall health.
In the coming years, ongoing research and real-world evidence will further elucidate the long-term benefits and safety profile of semaglutide for weight management. With continued advancements in obesity treatment, patients can look forward to more effective and personalized approaches to achieving sustainable weight loss and improving their quality of life.
Summary:
In summary, the official approval status of semaglutide for weight loss by health authorities is a significant development in the field of obesity medicine. The FDA’s approval in the United States and the CHMP’s positive recommendation in the EU represent important milestones in the recognition of semaglutide as an effective treatment for weight management. As more health authorities around the world evaluate semaglutide for weight loss, healthcare providers and patients can expect to have access to a new class of medications that offer innovative solutions for addressing the global obesity epidemic.
With ongoing research and real-world evidence, semaglutide is poised to play a key role in helping individuals achieve sustainable weight loss and improve their overall health. As the field of obesity medicine continues to evolve, semaglutide stands out as a promising option for addressing the complex challenges of obesity and providing patients with effective strategies for long-term weight management.
Ultimately, the official approval of semaglutide for weight loss by health authorities opens up new possibilities for healthcare providers to better support patients in their weight loss journey and pave the way for a healthier future for individuals struggling with obesity.
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Losing that fat from your belly can be tough, but it is not impossible. It is a lengthy procedure. Weight loss is not something that happens immediately. You must put in consistent effort to lose weight. Begin with small steps. Even if you just run 1 kilometer a day, you would have covered 365 kilometers by the end of the year. Even a small effort will pay off in the long run. It is important to persevere in this journey without losing hope. Maintain your attention on your objective. It will make the whole process go more smoothly. One thing to keep in mind is to NEVER GIVE UP. Why Belly Fat is Dangerous 👉👉https://youtu.be/cD-p-ccnJ2o How To Wake Up Early Without An Alarm | Perfect Your Morning Routine in 4 Steps 👉👉https://youtu.be/1bXPcw64zkk #shivangidesai #fitbharat #weightloss #zumba #joy #fitness #diet #exercise #motivation #fitlife #selfcare #health #madeesay #fitnessmotivation #fitnessfreaks #zumbafitness #zumbalove #zumbavirtual #zumbatime #zumbadance
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