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In this episode, Dr. Michele Matarazzo interviews Prof. Tom Foltynie about the recently published phase 3 clinical trial of exenatide as a disease-modifying therapy for Parkinson’s disease in The Lancet. While the findings were disappointing, ongoing post-hoc analyses aim to understand the discrepancy with previous phase 2 results and explore how they might shape the future of exenatide and other GLP-1 agonists in neurodegenerative disorders. Read the article. (https://pubmed.ncbi.nlm.nih.gov/39919773/)
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Actress Chrissy Metz reveals she's suffered from years of depression due to her weight. The This Is Us actress is featured on the cover of People magazine out Friday, admits she fell into a "soul crushing" 10-year spiral of weight gain and depression. On her hit show, the character also struggles with body image issues. "I wouldn't have this role if I had already lost weight. Now it's about telling a story of a woman struggling with her weight, just as I have and still am," she told People. #InsideEdition
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