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Presentation by Robert Busch, MD 1. Identify appropriate pharmacologic treatment options for individualized T2DM management using guideline- and trial-based evidence and accounting for patient presentation. How do you tailor therapy? 2. Explain the new indications for commonly used diabetes medications (SGLT-2’s, GLP’s) 3. Discuss new and emerging therapies for the management of T2DM Recorded live, April 6, 2024 as part of the Richard C. Staab, DO Memorial Symposium. Presented by Oklahoma State Medical Center Department of Internal Medicine in partnership with the Osteopathic Founders Foundation and Saint Francis Health System. This recording is viewable for reference and educational purposes only, and does not qualify for CME credit. For upcoming CME opportunities, please visit https://osteopathicfounders.org/education/cmeecc/

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Pharmaceutical interventions for weight loss & healthy weight management have become a topic of discussion over the last few months. One of the drugs which has created a spur in the market is GLP-1 RA. & there have been lot of questions “ Should GLP-1 RA be part of the treatment protocol for weight loss?” “ IS GLP-1 an anti-diabetic drug or a weight loss drug?” These questions are specifically coming from weight loss companies who believe that these drugs would have numerous side effects. Therefore, it becomes super important to understand the interaction between gut microbiome & these drugs. We all know that GLP-1 is an incretin hormone secreted by your gut microbiome that plays a key role in regulating satiety & blood sugar response. As such, the drug is being prescribed for glycemic control at present. However, the question still looms around if these drugs in small doses could promote healthy weight management? While this is a grey area, it is important to understand that not only does weight gain increase risk of insulin resistance but also insulin resistance caused by bad fats or functional loss of nitric oxide production could lead to weight gain. This insulin resistance derived weight gain is connected with hypothyroidism. Thyroid is the most essential hormone & our gut microbiome plays an important role in stimulating TSH & converting T4 to T3. Generally T4, the inactive form -T4 is converted into active form T3 with the help of type 2 deiodinase. Insulin resistance reduces the function of this enzyme, preventing the conversion of T4 to T3. This results in low levels of T3 & hence there is less T3 that could dock on the thyroid receptor expressed on cell membrane which disrupts cellular communication & interferes with metabolic activity, leading to weight gain. Controlling the blood sugar response could regulate the thyroid functions & may contribute to healthy weight management To really evaluate the efficacy of GLP-1 RA, it is important to understand the interaction between your gut microbiome & these drugs Citations https://pubmed.ncbi.nlm.nih.gov/17505150/ https://pmc.ncbi.nlm.nih.gov/articles/PMC8793908/ https://pmc.ncbi.nlm.nih.gov/articles/PMC6354569 #weightloss #weightlossjourney #weightlosstips #weightlossdiet #glp1 #glp1medication #glp1support #glp1weightloss #glp1community #obesity #obesitymedicine #obesityawareness #obesityawareness #obesitycontrol #obesityfreeindia #ozempicweightloss #ozempicsideeffects #ozempicjourney

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Thanks for tuning in to the Redefining Strength Podcast! If you enjoyed this video and want to learn more, be sure to check out our podcast on your favorite streaming platform 🎧 Or listen at: 👉 https://redefiningstrength.com/podcast/ If you're enjoying the podcast and found it valuable reviews are super helpful to help this reach more people🙏. I really appreciate your support and look forward to bringing you more fitness hacks and tips in the future! If you're looking for more video content, be sure to subscribe to the main Redefining Strength YouTube channel at https://www.youtube.com/@redefiningstrengthOC where we post new videos every Sunday Thanks again for watching and we'll see you next week! 💪

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Have you ever found yourself scrolling through channels late at night, only to stumble upon a marathon of Shark Tank episodes? It’s easy to get sucked into the world of entrepreneurial pitches and high-stake investments, wondering which product will be the next big success story. One episode that especially caught our attention was when a group of entrepreneurs presented their revolutionary fat-eating pills on Shark Tank. This episode not only captured the interest of the sharks but also left viewers at home intrigued and skeptical about the effectiveness of these pills.

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As the entrepreneurs stepped into the tank and began to pitch their fat-eating pills, the sharks were immediately intrigued. The pitch centered around a new technology that claimed to target and break down fat cells in the body, helping individuals lose weight without any major lifestyle changes. The entrepreneurs presented compelling data and testimonials, showcasing the potential of their product to revolutionize the weight loss industry.

However, the sharks were not easily convinced. They grilled the entrepreneurs with tough questions about the science behind the pills, the potential side effects, and the market competition. Despite the entrepreneurs’ confident responses, the sharks remained skeptical about the viability of the product and its ability to deliver on its promises.

The Moment of Truth

As the tension in the tank reached its peak, one of the sharks decided to take a leap of faith and make an offer to invest in the fat-eating pills. This unexpected move surprised everyone, including the entrepreneurs themselves. The other sharks quickly followed suit, expressing their interest in the product and its potential to disrupt the weight loss industry.

In the end, after intense negotiations and deliberations, a deal was struck between the entrepreneurs and two of the sharks. The fat-eating pills had successfully secured the investment they needed to bring their product to market and prove its effectiveness to the world.

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Looking Ahead

As the episode came to a close, viewers were left with a mix of excitement and skepticism. Will the fat-eating pills live up to their promises, or will they fall short of expectations? Only time will tell, but one thing is for sure – this episode of Shark Tank has left a lasting impression on all those who witnessed the dramatic pitch and unexpected outcome.

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In conclusion, the fat-eating pills episode of Shark Tank was a rollercoaster of emotions, as viewers were taken on a journey of doubt, intrigue, and ultimately, hope. Whether the product will become a game-changer in the weight loss industry remains to be seen, but one thing is certain – the entrepreneurial spirit and innovation showcased in this episode will continue to inspire viewers and entrepreneurs alike for years to come.

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