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View show notes here: https://bit.ly/3GJjQKz Become a member to receive exclusive content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Colleen Cutcliffe is an expert in molecular biology and co-founder of Pendulum Therapeutics, a company working to develop treatments for a variety of diseases by targeting the microbiome. In this episode, Colleen delves into the complexity of the microbiome, how it is tested, and how it changes over time. She explores how probiotics, prebiotics, and postbiotics affect the gut and makes a compelling case that well-developed products have the potential not only to enhance gut health but also to positively influence overall metabolic well-being. Colleen emphasizes the significance of a high-fiber diet in sustaining a thriving gut microbiome, shares insights on minimizing microbiome damage during antibiotic use, provides tips for fostering and preserving a healthy gut, and much more. We discuss: 0:00:00 - Intro 0:00:34 - Colleen’s background and current focus 0:03:08 - The basics of the microbiome 0:12:37 - The study of the human microbiome 0:17:42 - Categories of bacteria, and the implications on health of the rapid evolution of bacteria 0:27:51 - Methods for measuring and understanding the microbiome, and key indicators of microbiome health 0:39:52 - The important role of fiber for promoting gut health through the production of butyrate 0:47:21 - The case for manipulating gut bacteria via fecal microbiota transplant (FMT) 0:53:25 - Dynamics of the microbiome: the gut-brain connection and how antibiotics, nutrition, stress, and more impact the microbiome's diversity and function 0:59:16 - Factors that influence the vaginal microbiom 1:03:46 - The effect of gut microbes on obesity and challenges with fecal transplants in people 1:06:25 - Beneficial strains of gut bacteria and strains commonly found in probiotics 1:16:35 - The difference between a probiotic and prebiotic, and how CFUs are a measure of the “active ingredient” 1:21:47 - Considerations about how probiotic strains are produced, and more on the meaning of CFU 1:31:12 - Mitigating the effect of antibiotics on the microbiome 1:39:58 - What do we know about the effect of artificial sweeteners on the gut microbiome? 1:47:02 - Why Akkermansia is a keystone strain with implications for metabolic health and an individual’s response to dietary interventions 1:58:14 - The essential steps necessary to develop a robust probiotic for optimal health support 2:01:45 - How Akkermansia helps control blood glucose, and potential implications of Akkermansia in weight loss, diabetes management, and more 2:22:46 - Pendulum Therapeutics’ commitment to rigorous product develop 2:29:54 - Details about the probiotic “Glucose Control” and other probiotics developed by Pendulum Therapeutics 2:38:43 - Further studies of Akkermansia that have been proposed or are underway -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: https://peterattiamd.com/terms-of-use/

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Apple cider vinegar (ACV) has been gaining popularity in recent years for its various health benefits, particularly for weight loss. Recently, a new product called Simply Health ACV Keto appeared on Shark Tank, a popular television show where entrepreneurs pitch their products to a panel of investors. In this episode breakdown, we will discuss the details of the pitch, the reactions of the sharks, and whether Simply Health ACV Keto was able to secure a deal.

Product Pitch

The founders of Simply Health ACV Keto entered the Shark Tank with confidence, touting their product as a revolutionary weight loss supplement that combines the benefits of apple cider vinegar and the ketogenic diet. They claimed that by taking their product, users could experience rapid weight loss, increased energy, and improved overall health.

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According to the founders, Simply Health ACV Keto is made with all-natural ingredients and is free of any harmful chemicals or additives. They emphasized that their product was backed by scientific research and had already received positive reviews from satisfied customers.

To demonstrate the effectiveness of their product, the founders shared impressive before and after photos of individuals who had used Simply Health ACV Keto and achieved significant weight loss results. They also presented data on the growing market for health and wellness products, highlighting the potential for strong sales and customer retention.

Shark Reactions

Initially, the sharks seemed intrigued by the potential of Simply Health ACV Keto and praised the founders for their innovative approach to weight loss. However, as the pitch progressed, some of the sharks raised concerns about the lack of clinical evidence supporting the effectiveness of the product.

Mark Cuban questioned the founders about the safety and regulatory compliance of Simply Health ACV Keto, while Lori Greiner expressed skepticism about the long-term sustainability of the business. Kevin O’Leary, known for his tough negotiation tactics, grilled the founders on their sales projections and manufacturing processes.

In the end, the sharks were divided in their opinions on Simply Health ACV Keto. While some saw the potential for growth and profitability, others were hesitant to invest without more concrete evidence of the product’s efficacy.

Deal or No Deal?

After much deliberation, the founders of Simply Health ACV Keto ultimately left the Shark Tank without a deal. While they received some interest from the sharks, none were willing to commit to an investment without further validation of the product’s claims.

Despite the setback, the founders remained optimistic about the future of Simply Health ACV Keto and pledged to continue working on improving their product and expanding their customer base. They thanked the sharks for their feedback and vowed to return stronger than ever.

In conclusion, the episode featuring Simply Health ACV Keto on Shark Tank was a rollercoaster of emotions for both the founders and the sharks. While the product showed promise, it ultimately failed to secure a deal due to concerns over its efficacy and long-term viability. Only time will tell if Simply Health ACV Keto can overcome these obstacles and become a successful player in the competitive health and wellness industry.

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#LipoJaro #LipoJaroReviews #GoodGenuineReviews LipoJaro Review (May 2025) Legit Weight Loss Supplement or Scam? In this video, we dive deep into LipoJaro, a popular weight loss supplement. Is it a legitimate product or just another scam? We’ll explore its ingredients, user reviews, potential side effects, and the company's refund policy to help you make an informed decision. Stay tuned to find out if LipoJaro is worth your time and money! HOW TO GET REFUND- VISIT LINKS 1. How to Refund on PayPal? Step-By-Step Guide on the Refund Policy https://www.freshbooks.com/hub/payments/how-to-refund-on-paypal 2. How to get a refund for a fraudulent credit card transaction https://www.bankrate.com/finance/credit-cards/how-to-refund-fraudulent-credit-card-transaction/ 3. How to check whether a product is genuine or not? https://iotbyhvm.ooo/how-to-check-whether-a-product-is-genuine-or-not/ Thanks for watching! Good Genuine Reviews #LipoJaro #LipoJaroReview #LipoJaroReviews #IsLipoJaroLegit #IsLipoJaroScam #NaturalWeightLoss #SupplementReview