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Watch the full episode and view show notes here: http://bit.ly/3Tap47T Become a member to receive exclusive content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ In this “Ask Me Anything” (AMA) episode, Peter focuses the discussion on two topics getting a lot of attention recently. He first dives deep into GLP-1 agonists, most notably semaglutide and tirzepatide, which originally came to market as diabetes drugs but are now being studied and prescribed for weight loss. He walks through the data and compares the effectiveness of the two drugs, the side effects, and perhaps more importantly, his reservations around wide use of these drugs and who he would consider to be a candidate for them. Next, Peter discusses how metformin, another drug originally brought to market for diabetes management, gained popularity as a potential longevity drug even for non-diabetics. Peter gives his take on this possibility and reviews data from a more recent study investigating the question of whether metformin should be used for general “geroprotection.” In this sneak peek, we discuss: 00:00 - Intro 00:08 - The hype around semaglutide, tirzepatide, and other GLP-1 agonists for weight loss 04:09 - Overview of GLP-1 agonists and why these drugs are getting so much attention 12:20 - Defining the term “geroprotective” 14:08 - Semaglutide: background, brand names, indications, and more 19:10 - Tirzepatide: background, brand names, indications, and more In the full episode, we also discuss: -How semaglutide and tirzepatide compare in their efficacy in terms of weight loss and other metabolic health metrics; -Data showing sustained weight loss and improved metabolic metrics with after more than a year of using semaglutide and tirzepatide; -What happens to body weight when a patient discontinues the medication?; -Noteworthy side effects of GLP-1 agonists and similar classes of drugs; -Increased resting heart rate and other concerning trends in patients using GLP-1 agonists; -Changes in body composition (body fat and lean muscle) in patients on GLP-1 agonists; -Possible reasons for the loss of lean muscle mass and tips for protecting lean mass; -GLP-1 agonists and thyroid cancer; -Who might be a candidate for GLP-1 agonists?; -The large financial cost of this class of drugs; -Metformin as a geroprotective drug: origin of the idea that metformin could be a longevity agent even for non-diabetic patients; -A 2022 study on metformin sheds more light on the question of whether metformin should be used for “geroprotection” in non-diabetics; -Peter’s current approach with metformin for his patients; and -More. -------- About: The Peter Attia Drive is a weekly, ultra-deep-dive podcast focusing on maximizing health, longevity, critical thinking…and a few other things. With over 45 million episodes downloaded, it features topics including fasting, ketosis, Alzheimer’s disease, cancer, mental health, and much more. Peter is a physician focusing on the applied science of longevity. His practice deals extensively with nutritional interventions, exercise physiology, sleep physiology, emotional and mental health, and pharmacology to increase lifespan (delay the onset of chronic disease), while simultaneously improving healthspan (quality of life). Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies.

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Do you really need supplements for weight loss? Weight loss supplements have no magic in it that can melt your fats. Diet management and calorie expenditure will help you lose fats. A normal person with a BMI under 30 without any medical condition do not need to take any sort of weight loss supplements. If someone’s BMI is more than 35 or 30 with metabolic diseases like diabetes, hypertension, high cholesterol levels etc then you might need these supplements along with diet management and exercise but this is also very personalized decision to take (depends on person’s lifestyle, eating habits, goals) . So next time don’t waste your money on supplements rather than invest in something that is valuable for your health weight loss journey. . Comment below if you have used any weight loss supplements and share your experience? . ➡️ Save this so you won’t forget. ➡️ Share with someone you know who needs to hear this. ➡️ Follow me for more tips. To book your Appointment: WhatsApp: 0337-1411978 Instagram: @nutrichdiet #onlinedietplans #dietonline #nutritionist #nutritioncoach #diet #dietitian #nutrichdiet #weightloss #dietplan #losingweight #diettips

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Click Here To Buy - https://www.thorsupplement.com/essential-keto-chemist-warehouse-buy/ That is the alarming condition for any individual to lose weight. But the next challenge is to choose the right and effective weight loss supplement. Additionally every supplement is not chemical free or more effective for weight loss, in that condition what to do? Here comes Essential Keto Gummies, the most vital and powerful weapon in the field of supplements for weight loss. In the market there are many keto products for weight loss. The process of ketosis can be achieved by using keto diet which is a low-carb diet. In ketosis, with a low-carb diet, the body burns fat instead of carbohydrates. https://www.thorsupplement.com/essential-keto-chemist-warehouse-buy/ If you want a keto diet formula to boost the process of ketosis in the body, then, you need to grab hands on Essential Keto Gummies. The intention of Essential Keto Gummies is not only to lose weight from the body but it also boosts the mind's wellbeing, uplifts the temper and stays them restful.

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WHERE TO FIND DR. ROBERT CYWES and SHERYL FOX RD: INSTAGRAM: https://www.instagram.com/carbaddictiiondoc FACEBOOK: https://www.facebook.com/carbaddictiondoc/ TIKTOK: https://www.tiktok.com/@carbaddictiondoc Websites: https://www.obesityunderstood.com https://www.weighlitepro.com We try to keep this content free as a service to you. If our content resonates and you can afford a buck or more: Donate to our 501(c)3 NON-PROFIT CHARITABLE ORGANIZATION PayPal ▶[email protected] PATREON ▶ https://bit.ly/2Xj0gBm ROBERT CYWES M.D., PhD and SHERYL FOX RD ARE clinically PRACTITIONERS in Florida and COVER THE ENTIRE USA AND WORLD VIA TELEHEALTH. The mission of our media content is educating the public about a CARBOHYDRATE ADDICTION approach to treating obesity, diabetes and metabolic syndrome. Understanding the importance of replacing carbs in your diet with REAL FOOD while simultaneously replacing carbs as a toxic, harmful response to emotional tension with a more effective diverse healthy set of emotion management tools for lifelong sustainability of mental and physical health, happiness and well-being. Converting people from toxic sugar burners to healthy fat (keto) burners while addressing the CAUSE of addiction to carbs from an emotion management perspective. Sometimes using obesity surgery and devices as tools along the way, and helping people who have had bariatric surgery stay healthy and not relapse Set up a consultation if you are looking for more sustainable ways to treat obesity, diabetes, metabolic syndrome, cholesterol issues and thyroid disease. Even if you are doing great but need physician confirmation or if you are considering or struggling after Bariatric Surgery we can assist you getting back on track. TEXT, WHATSAPP or CALL to leave a message on our “batphone” +1 5615170642 from anywhere in the world. We do secure telehealth, Zoom and Whatsapp phone and video consults all over the world. If appropriate we can order bloodwork and Coronary Artery Calcium Scores as part of a consultation. Please always feel free to record your consult but inform Dr Cywes and Sheryl. For COLLABORATIONS please email me: [email protected] Also follow @carbaddictionmom and @carbaddictionrd on Instagram and Facebook to see how we live our lives and to understand how we raise our son in a carnivore family If you would like to send products or books for us to review, or even a card or letter, send HERE: Dr Robert Cywes, 601 University Blvd 206, Jupiter, Florida 33458 USA. If you practice in the Low Carb Metabolic Space in any manner, I urge you to join SMHP: the Society for Metabolic Health Practitioners: SMHP Accreditation (thesmhp.org) together we are one voice that cannot be ignored **DISCLAIMER: Any information on diseases and treatments available at this channel is intended for general guidance only and must never be considered a substitute for advice provided by a doctor or qualified healthcare professional. Always seek the advice of your physician or qualified health care professional with questions you may have regarding your medical condition. This site and these videos exist to provide information and support about nutritional health and do not provide medical advice and should not be thought to provide medical advice. We can only give medical advice if you establish yourself as a registered patient and consult with us in our medical practice - JSAPA. We always recommend working with a team of knowledgeable and experienced practitioners, including a physician such as Dr Cywes and a Registered Dietician such as Sheryl Fox in our practice. Do not self-diagnose. Always seek medical guidance when you have a medical condition. -------- #diet #keto #carnivore #healthy #obesity #diet #obesidadeinfantil Although all measures are taken to ensure that the content of the YouTube channel is accurate and up-to-date, all information contained on it is provided ‘as is’. We make no warranties or representations of any kind concerning the accuracy or suitability of the information contained on this channel. Robert Cywes and his team may at any time and at their sole discretion change or replace the information available on this channel. To the extent permitted by mandatory law, Robert Cywes shall not be liable for any direct, incidental, consequential, indirect or punitive damages arising out of access to or use of any content available on this channel, including viruses, regardless of the accuracy or completeness of any such content.

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