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Are GLP-1 weight loss drugs the solution we've been waiting for—or just another manifestation of diet culture in disguise? In this episode 42, "GLP-1 Medications Explained: What You Need to Know in 2025," of the How to Fitness Podcast, we dive into the hype, hope, and hard truths surrounding medications like Ozempic and Wegovy. Join us as we break down the science behind GLP-1 drugs, discuss their benefits for obesity and metabolic health, and explore the potential risks and ethical dilemmas tied to their use. From celebrity endorsements to compounding pharmacies and societal pressures, this episode uncovers the complexities of these groundbreaking yet polarizing treatments. Tune in to get the facts, hear real-world insights, and learn how to navigate this evolving topic with clarity. TIMESTAMPS: 00:00 Introduction and Personal Opinions on Weight Loss Medications 00:23 Welcome to the How to Fitness Podcast 01:07 Revisiting the Ozempic Revolution 03:04 Understanding GLP-1 Medications 04:19 Mechanisms and Effects of Semaglutide 07:00 Personal Experiences and Observations 10:22 The Broader Impact and Misconceptions 20:34 Celebrity Influence and Public Perception 23:16 Exploring Telehealth and Accessibility 23:57 Exploring Telehealth Weight Loss Options 28:15 Compounding Pharmacies: Pros and Cons 29:58 The Risks of Compounded Medications 34:22 The Social Implications of Weight Loss Drugs 39:33 Long-Term Use and Ethical Considerations RESOURCES MENTIONED: 🟡 The Ozempic Revolution: Exploring the Soaring Popularity of GLP-1 Drugs https://www.buzzsprout.com/2171581/episodes/12924933 🟡 What are "GLP1 Agonists"? https://glp1.guide/content/what-are-glp1-agonists/ 🟡 GLP‐1 signaling in the brain https://pmc.ncbi.nlm.nih.gov/articles/PMC8820188/?ref=glp1.guide 🟡 FDA’s ongoing evaluation of reports https://www.fda.gov/drugs/drug-safety-and-availability/update-fdas-ongoing-evaluation-reports-suicidal-thoughts-or-actions-patients-taking-certain-type?ref=glp1.guide 🟡 Drug ad spending https://www.cnbc.com/2024/04/03/weight-loss-diabetes-drug-ad-spending-tops-1-billion.html 🟡 GLP-1 Adverse Events https://www.mdpi.com/1424-8247/17/2/199?ref=glp1.guide 🟡 FDA’s Concerns with Unapproved GLP-1 Drugs Used for Weight Loss https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/fdas-concerns-unapproved-glp-1-drugs-used-weight-loss 🟡 Once-Weekly Semaglutide in Adults with Overweight or Obesity https://www.nejm.org/doi/full/10.1056/NEJMoa2032183 🟡 The New Yorker https://www.newyorker.com/magazine/2023/03/27/will-the-ozempic-era-change-how-we-think-about-being-fat-and-being-thin Listen to our How to Fitness podcast on your favorite platform! https://howtofitness.buzzsprout.com/2171581/episodes We’d love to hear your thoughts! Share your feedback or questions in the comments below! And while you’re here, don’t forget to subscribe to our podcast and hit that notification bell so you never miss an episode. STAY CONNECTED 🟡 Michael Ulloa: https://www.michaelulloa.com/ Instagram: https://www.instagram.com/michaelulloapt 🟡 Kate Lyman: https://www.katelymannutrition.com/ Instagram: https://www.instagram.com/klnutrition/ Thank You for Listening to How to Fitness Podcast with Michael Ulloa and Kate Lyman! #howtofitness #howtofitnesspodcast #healthandfitnesspodcast #bustingnutritionmyth

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Semaglutide has recently emerged as a promising treatment for weight loss, with studies showing significant reductions in body weight in individuals with obesity. However, one of the key questions that researchers and healthcare providers are still trying to answer is: What is the optimal dose of semaglutide for weight loss?

Understanding Semaglutide

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that is FDA-approved for the treatment of type 2 diabetes. However, recent studies have found that semaglutide can also be effective in promoting weight loss. GLP-1 receptor agonists work by mimicking the effects of GLP-1, a hormone that helps regulate blood sugar levels and appetite.

When used for weight loss, semaglutide is typically administered via a subcutaneous injection once a week. The dose of semaglutide can vary depending on the individual’s weight, tolerance to the medication, and other factors.

Finding the Right Dose

One of the challenges in determining the optimal dose of semaglutide for weight loss is finding the right balance between efficacy and side effects. Higher doses of semaglutide may lead to greater weight loss, but they may also increase the risk of adverse effects such as nausea, vomiting, and diarrhea.

On the other hand, lower doses may be more tolerable but may not be as effective in promoting weight loss. Healthcare providers will need to closely monitor patients’ response to the medication and adjust the dose as needed to achieve the best results.Health Keto Gummies Promoting Wellness Through Ketosis





Personalized Treatment Approach

Given the variability in individual responses to semaglutide, a personalized treatment approach is crucial in finding the optimal dose for weight loss. Healthcare providers will need to take into account factors such as the patient’s weight, age, medical history, and potential drug interactions when determining the appropriate dose of semaglutide.

It may take some trial and error to find the right dose for each individual, but the potential benefits of weight loss with semaglutide can be significant for those struggling with obesity.

Future Research Directions

As researchers continue to study the effects of semaglutide on weight loss, future research directions may focus on exploring different doses and dosing regimens to maximize the benefits of the medication while minimizing side effects. Additionally, studies may investigate the long-term effects of semaglutide on weight maintenance and overall health outcomes.

Overall, the field of semaglutide for weight loss is still evolving, and healthcare providers will need to stay updated on the latest research findings to provide the best possible care for their patients.

Summary and FAQ

In conclusion, finding the optimal dose of semaglutide for weight loss is a complex process that requires careful consideration of individual factors and close monitoring by healthcare providers. With a personalized treatment approach and ongoing research efforts, semaglutide holds promise as a valuable tool in the management of obesity.

Here are some frequently asked questions about semaglutide for weight loss:

1. What are the common side effects of semaglutide for weight loss?

2. How long does it take to see results with semaglutide?

3. Can semaglutide be used as a long-term weight loss solution?

4. Are there any contraindications for using semaglutide for weight loss?

5. How does semaglutide compare to other weight loss medications?

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