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With millions of people now taking GLP-1 agonists like Ozempic and Wegovy, I was curious to learn if there are known genetic mutations that predispose people to have serious side effects from these medications. So exploring the pharmacogenomic aspects of Ozempic and Wegovy. To answer these questions Dr. Josiah Allen is joining the show. Josiah Allen, PharmD, has spent over 15 years in the field of pharmacogenomics, beginning at the Mayo Clinic where he helped develop the GeneSight test. As a founding employee and the first medical science liaison at Assurex Health, he helped GeneSight become one of the fastest growing molecular diagnostic tests in history. He later served as director of medical affairs at OneOme and now works at St. Elizabeth Healthcare in Edgewood, KY, as a precision medicine pharmacist and PGY2 Clinical Pharmacogenomics pharmacy residency program director. He earned his bachelor's degree in psychology from Wheaton College and his Doctor of Pharmacy degree from the University of Minnesota. Topics Covered: The basics of pharmacogenomics and its role in personalized medicine. How genetic mutations, like those in the RET gene, influence medication risks. The pharmacogenomics of GLP-1 agonists (like Ozempic and Wegovy), including their contraindications for patients with RET mutations. Insights into the overlap between ACMG secondary findings and pharmacogenomic implications. Case studies illustrating the real-world impact of pharmacogenomics. Key Takeaways: GLP-1 agonists, such as Ozempic and Wegovy, carry a black box warning due to an association with thyroid cancer, particularly in individuals with RET gene mutations. Over one-third of the ACMG secondary findings genes have pharmacogenomic implications, emphasizing the need for clinicians to integrate genetic insights into prescribing practices. Pharmacists and geneticists need closer collaboration to bridge the gap between clinical genomics and pharmacogenomics for safer medication use. Get ready, genetic nerds—another brand-new episode of DNA Today drops next Friday! You can always count on us to deliver fresh content every Friday. While you wait, why not dive into our library of over 300 episodes? Binge them all on Apple Podcasts, Spotify, our website, or wherever you love to listen—just search “DNA Today.” DNA Today is hosted and produced by Kira Dineen, MS, LCGC, CG(ASCP)CM . Our Video Lead is Amanda Andreoli. Our Social Media Lead is Kajal Patel. Our Outreach Intern is Liv Davidson. And our logo Graphic Designer is Ashlyn Enokian, MS, CGC. See what else we are up to on Instagram, X (Twitter), BluSky, Threads, LinkedIn, Facebook, YouTube all at DNATodayPodcast. Our website is DNAToday.com. Questions/inquiries can be sent to [email protected].

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We discuss Gunna's fitness journey post-jail and debate supplements versus the natural approach to weight loss. Ultimately, it's about finding what works best for you! #Gunna #WeightLoss #Supplements #FitnessJourney #NaturalWeightLoss #Transformation #WorkoutMotivation #HealthAndFitness #Bodybuilding #FitnessTips

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Samantha Martin’s Keto Journey on Shark Tank was a groundbreaking episode that left viewers in awe of her determination and success. Keto diets have gained immense popularity in recent years for their promising results in weight loss and improved health. As Samantha took her unique Keto product to the Shark Tank, she faced the scrutiny of the investors but ultimately emerged victorious. Let’s delve into the insights and outcomes of Samantha Martin’s Keto Journey on Shark Tank.

The Pitch

Samantha Martin walked into the Shark Tank with a pitch that caught the attention of all the investors. She confidently presented her Keto product, detailing its benefits and how it could revolutionize the weight loss industry. The Sharks listened intently as Samantha shared her personal Keto journey, highlighting the success she had achieved with the help of her product. Her passion and knowledge shone through, leaving a lasting impression on the investors.

Throughout her pitch, Samantha emphasized the science behind the Keto diet and how her product was designed to support individuals following this lifestyle. She highlighted the potential market for her product, showcasing research and statistics to back up her claims. The Sharks were intrigued by the unique approach Samantha had taken with her Keto product, and they were eager to learn more about its development and effectiveness.

As Samantha concluded her pitch, she made a compelling case for why her Keto product deserved investment. She painted a clear picture of the impact it could have on people’s lives and how it could disrupt the weight loss industry. The Sharks were impressed by Samantha’s dedication and vision, leading to a tense and exciting negotiation process.

The Negotiation

As the Sharks began to ask questions and dig deeper into Samantha’s Keto product, it became evident that they saw potential in what she had to offer. They admired her foray into the competitive health and wellness market and recognized the uniqueness of her product. Each Shark brought their own perspective to the negotiation table, offering insights and feedback that pushed Samantha to defend her business and showcase its strengths.

Throughout the negotiation, Samantha remained composed and confident, fielding the Sharks’ questions with grace and intelligence. She stood her ground on the value of her Keto product, highlighting its benefits and competitive edge. The tension in the room was palpable as the Sharks deliberated on whether to invest in Samantha’s business, leading to a climactic moment that would determine the outcome of her Keto Journey on Shark Tank.

Ultimately, Samantha’s negotiation skills and passion won over the Sharks, as one investor saw the potential for significant returns and made her an offer she couldn’t refuse. The deal that was struck in the Shark Tank would propel Samantha’s Keto product to new heights, opening doors to partnerships and opportunities that would shape the future of her business.

The Outcome

After striking a deal in the Shark Tank, Samantha Martin’s Keto Journey took a new direction as she partnered with a Shark who believed in her vision. The resources and expertise brought by the investor enabled Samantha to scale her business and reach a wider audience. Her Keto product gained traction in the market, garnering positive reviews and testimonials from satisfied customers.

Thanks to the exposure and validation from Shark Tank, Samantha’s Keto Journey turned into a success story that inspired many aspiring entrepreneurs. She became a role model for individuals looking to make an impact in the health and wellness industry, showcasing the power of determination and innovation. Samantha’s journey serves as a reminder that with hard work and vision, anything is possible.

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As Samantha Martin continues to expand her Keto product line and make a difference in people’s lives, her legacy on Shark Tank remains a testament to the journey of a passionate entrepreneur who dared to dream big and make it a reality.

**FAQ**

1. What inspired Samantha Martin to start her Keto journey on Shark Tank?

Samantha was inspired by her personal experience with the Keto diet and the positive impact it had on her health and well-being. She saw an opportunity to create a product that could help others achieve similar results and decided to take her Keto journey to the Shark Tank for a chance to scale her business.

2. How did Samantha Martin’s negotiation skills influence the outcome of her Keto journey on Shark Tank?

Samantha’s negotiation skills played a crucial role in securing a deal with a Shark who believed in her vision and the potential of her Keto product. Her ability to articulate the value of her business and defend its competitive edge impressed the investors and ultimately led to a successful partnership.

3. What lessons can aspiring entrepreneurs learn from Samantha Martin’s Keto journey on Shark Tank?

Samantha’s journey on Shark Tank serves as a valuable lesson for aspiring entrepreneurs, highlighting the importance of passion, determination, and strategic thinking in building a successful business. Her experience showcases the power of believing in one’s vision and persevering through challenges to achieve success.

What Is The Best Weight Loss Diet

537 Cal | 52g P | 49g Carb | 14g F I was looking for that familiar taste of home this week… this one hits! Follow 👉 @BetterCheatMeals if you want to hit your nutrition goals and eat the food you love. 👊 Made with 2½ cup (600 ml) glass containers, link in bio Servings: 4 🥧 Ingredients -1½ lb (680 g) ground/minced beef (95/5 or better) -salt and pepper to taste -2 onions (finely diced) -2 carrots (diced small) -3 garlic cloves (minced) -2 tbsp (30 g) tomato paste -2 beef stock cubes dissolved in 1 cup hot water -2 tbsp (30 g) Worcestershire sauce -1 tbsp (15 g) soy sauce -1 tbsp (15 g) red wine vinegar -2 cups (300 g) frozen mixed vegetables Potato & Cheese Top -2 lbs (1 kg) lotatoes (or Russett) -½ cup (110 ml) protein boosted almond milk -salt and black pepper -1 cup (100 g) mozzarella cheese Instructions -Microwave diced potatoes in a microwave safe bowl with ¼ cup (60ml) water for 8-10 minutes until tender. Mash with milk until smooth, season with salt and pepper. -In a large pan, brown beef over medium-high heat. Break up any lumps. Season with salt and pepper. -Add onions, carrots, and garlic. Cook until onions are golden and carrots soft. -Add wine/vinegar, scraping up browned bits from pan. -Stir in tomato paste and cook 2 minutes until darkened. -Add stock, Worcestershire sauce, soy sauce, and frozen veg. Simmer for a minute or two, but leave saucy. Season to taste. -Transfer to baking dishes, top with mash and cheese. -Bake at 200°C (400°F) for 7-10 minutes until the cheese melts and starts to brown. -Let rest 5 minutes before serving to let it cool down. Notes -If Lotatoes/Carisma low-carb potatoes aren’t available, cauliflower florets can be used as a low-carb alternative or swap for regular potatoes -If using regular potatoes, reduce to 1 lb for comparable macros #mealprep #weightloss #fatloss

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Today, Jason Phillips shows how to lose fat without losing muscle. If you're in a fat loss diet plan or weight loss plan currently, you'll want to check out his nutrition advice on how to lose fat and get lean and ripped effectively. This is how to keep muscle while cutting. Presented to you by the best nutrition course and online nutrition coaching certification in the health and fitness coach industry, Nutritional Coaching Institute. YOUR CHEAT SHEET: https://coachingcheatsheet.com/optin-460785161611114819997 More resources: Join the Nutrition Coaching Secrets FB group: www.facebook.com/groups/nutritioncoachingsecrets/ Watch this video next: https://youtu.be/WSQXo8dZXho See you in the next video! FAQs: How To Build A Nutrition Coaching Business: https://youtu.be/WSQXo8dZXho How To Get More Nutrition Coaching Clients: https://youtu.be/Kag6LW7O9JU How To Get Your Nutrition Clients Better Results: https://youtu.be/KFSr7W8BvWk Is Body Recmposition Possible? : https://youtu.be/h6Y32-vQoAQ Should Your Clients Track Macros: https://youtu.be/3BBCLEKPU40 How To Deal With Noncompliant Clients: https://youtu.be/w4jtEbwofVo #nutritioncoaching #shorts #jasonphillips

Advanced Techniques To Speed Up Weight Loss Beyond Keto Intermittent Fasting

Looking to lose weight without Ozempic? Check out this video for a better solution to achieve your weight loss goals! Looking for weight loss options better than Ozempic? Watch this video to learn about effective alternatives for managing your weight.Looking for a weight loss solution better than Ozempic? Watch this video for an alternative approach to shedding pounds and improving your health.Are you looking for a natural way to lose weight without relying on Ozempic or other GLP-1 medications? In this video, we’ll reveal the top 12 foods, herbs, and lifestyle changes that help with weight loss naturally—without muscle loss or harmful side effects!You'll learn about thermogenic foods, hormone-balancing herbs, metabolism-boosting exercises, and powerful supplements like berberine, cinnamon, and green tea—all backed by science!Many weight loss drugs like Ozempic, Wegovy, and Mounjaro come with risks, including muscle loss and long-term health concerns. But what if you could lose weight naturally, boost energy, feel younger, and improve gut health—all while eating delicious food?✅ What You'll Learn in This Video:✔️ The best natural fat-burning foods (better than Ozempic!)✔️ How to balance hormones like insulin, cortisol, and thyroid for weight loss✔️ The top metabolism-boosting supplements that support fat burning✔️ Why building muscle is key to long-term weight loss✔️ The truth about GLP-1 drugs and their side effects🔔 Subscribe for more health & weight loss tips! Don't forget to like, comment, and share if you found this video helpful.#WeightLoss #OzempicAlternative #NaturalWeightLoss #FatBurningFoods #HormoneBalance #MetabolismBoost #HealthyLiving #WeightLossTips #Berberine #Cinnamon #GreenTea #GLP1 #FatBurning #Keto #IntermittentFasting #HealthyDiet