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Watch the full episode and view show notes here: http://bit.ly/3Tap47T Become a member to receive exclusive content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ In this “Ask Me Anything” (AMA) episode, Peter focuses the discussion on two topics getting a lot of attention recently. He first dives deep into GLP-1 agonists, most notably semaglutide and tirzepatide, which originally came to market as diabetes drugs but are now being studied and prescribed for weight loss. He walks through the data and compares the effectiveness of the two drugs, the side effects, and perhaps more importantly, his reservations around wide use of these drugs and who he would consider to be a candidate for them. Next, Peter discusses how metformin, another drug originally brought to market for diabetes management, gained popularity as a potential longevity drug even for non-diabetics. Peter gives his take on this possibility and reviews data from a more recent study investigating the question of whether metformin should be used for general “geroprotection.” In this sneak peek, we discuss: 00:00 - Intro 00:08 - The hype around semaglutide, tirzepatide, and other GLP-1 agonists for weight loss 04:09 - Overview of GLP-1 agonists and why these drugs are getting so much attention 12:20 - Defining the term “geroprotective” 14:08 - Semaglutide: background, brand names, indications, and more 19:10 - Tirzepatide: background, brand names, indications, and more In the full episode, we also discuss: -How semaglutide and tirzepatide compare in their efficacy in terms of weight loss and other metabolic health metrics; -Data showing sustained weight loss and improved metabolic metrics with after more than a year of using semaglutide and tirzepatide; -What happens to body weight when a patient discontinues the medication?; -Noteworthy side effects of GLP-1 agonists and similar classes of drugs; -Increased resting heart rate and other concerning trends in patients using GLP-1 agonists; -Changes in body composition (body fat and lean muscle) in patients on GLP-1 agonists; -Possible reasons for the loss of lean muscle mass and tips for protecting lean mass; -GLP-1 agonists and thyroid cancer; -Who might be a candidate for GLP-1 agonists?; -The large financial cost of this class of drugs; -Metformin as a geroprotective drug: origin of the idea that metformin could be a longevity agent even for non-diabetic patients; -A 2022 study on metformin sheds more light on the question of whether metformin should be used for “geroprotection” in non-diabetics; -Peter’s current approach with metformin for his patients; and -More. -------- About: The Peter Attia Drive is a weekly, ultra-deep-dive podcast focusing on maximizing health, longevity, critical thinking…and a few other things. With over 45 million episodes downloaded, it features topics including fasting, ketosis, Alzheimer’s disease, cancer, mental health, and much more. Peter is a physician focusing on the applied science of longevity. His practice deals extensively with nutritional interventions, exercise physiology, sleep physiology, emotional and mental health, and pharmacology to increase lifespan (delay the onset of chronic disease), while simultaneously improving healthspan (quality of life). Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies.

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There’s a dangerous myth floating around that people on GLP-1 medications like semaglutide or tirzepatide are just sitting around doing nothing while the weight magically falls off. As a woman over 50, I’m here to tell you — that couldn’t be further from the truth. In this video, I break down the realities of using GLP-1s: The side effects — from nausea to the rare but serious risks like gallstones and pancreatitis. The science behind weight set point theory and why our bodies resist weight loss. The unique challenges women face after 40, especially post-menopause, when blood sugar regulation becomes harder and the risks of heart disease and stroke go up. If you’ve ever felt shame for getting help… if you’ve been judged for using medication… or if you simply want a real, evidence-based perspective — this video is for you. You are not a failure. You are not weak. You’re choosing health. And that’s powerful. Let’s talk in the comments—your journey matters. #GLP1 #Semaglutide #Tirzepatide #WomensHealthOver40 #GLP1Journey #MenopauseWeightGain #SetPointTheory #WeightLossSupport #HealthNotHype Get my GLP-1 Checklist at https://aminata.store/shop/219a364c-e803-42e9-82de-7173179223f0

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A plethora of supplements inundate the market for weight loss, assuring a miraculous solution to weight loss issues with little or no effort at all. If you’ve tried most of the products on the market and seen little to no action or results, this product could be for you. It’s called Bio Science Keto Gummies, the ketogenic gummies that leave diet pill enthusiasts yearning for that missing link between ketosis and weight loss. And guess what? This product could be the missing piece. But how does Bio Science Keto Gummies bring back the missing link to weight loss success through ketosis? Keep reading to find out.

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In order to understand the effects of Bio Science Keto Gummies , it is essential to understand the meaning of ketosis. Ketosis is actually a metabolic state that occurs when the body breaks down fats into ketones to be used as fuel. This occurs when the body experienced alteration in energy production and use over long periods of time. Starting to follow a low-carb, high-fat ketogenic (keto) diet encourages the body to generate ketones for fuel. However, reaching and maintaining ketosis can be a challenge for many when it comes to dietary changes only. Hence, the formulation of exogenous ketone supplements such as Bio Science Keto Gummies came about.

Bio Science Keto Gummies with Ketones are made of exogenous ketones found in beta-hydroxybutyrate (BHB). These ketones are absorbed directly into the bloodstream and, therefore, used as the main source of energy for the body. This literally opens the door to losing weight faster by forcing the body into ketosis. It also boosts your energy levels and promotes mental automation.

Secondly, exogenous ketones, like the ketones in Bio Science Keto Gummies, keeps your appetite and cravings at bay for your keto diet and prevents you from falling out of ketosis, aiding greater fat-burning and more efficient weight loss results versus dieting alone. Finally, some research indicates that exogenous ketones also have anti-inflammatory and neuroprotective benefits.

How to Incorporate Bio Science Keto Gummies into Your Routine

Everyone knows how difficult it is to reduce their body fat percentage. Now that you know how Bio Science Keto Gummies work on a molecular level, let’s talk about whether you should take Bio Science Keto Gummies. Firstly, depending on the needs and goals of the person, the dosage for each person can be different, but generally one to two gummies were best to reduce your weight. It is better to stick to the dose that is prescribed on the product label. The fatty acid ketones are the major components from Bio Science Keto Gummies. Finally, to make sure that your supplement routine is healthy and does not have negative effects, it is best to consult your doctor before taking any supplement.

It can’t be stated enough; alongside taking the supplement, maintain a balanced Paleolithic diet consisting mostly of whole foods (with sufficient vegetable content) along with healthy fats and lean proteins, engage in physical activity on a regular basis, and keep your body hydrated. These steps combined can lead to a multitude of positive health outcomes. Maintain consistency in taking your Bio Science Keto Gummies to help achieve your weight loss goals.

I would like to make it clear that Bio Science Keto Gummies for Weight loss are not a miraculous supplement like readily available. Using Bio Science Keto Gummies for Weight loss can help you with your journey, but you need to follow healthy food habit, some light exercise, and lifestyle changes to see permanent results. Though it is an effective supplement, but everyone’s effect will be different. Do not expect immediate results from this product as our body need some time to show effective outcome. But, if you remain committed towards it then you will easily achieve the weight and body shape you want.

Potential Side Effects and Precautions

However, before buying any new supplement, it is important to understand the pros and cons of the product. Prior to using the Bio Science Keto Gummies any person should always be aware of potential side effects and precautions. The good news is that Bio Science Keto Gummies can be taken by most people without experiencing any severe side effects. That said, a few people might notice their body responding to a new supplement with digestive issues or headaches and fatigue. These symptoms are usually temporary and will subside as your body becomes accustomed to the supplement.

Additionally, users will need to follow the proper usage guidelines and not exceed the daily recommended dosage so as to curtail any side effects. Anyone with pre-existing conditions or taking any kind of medication should consult a physician in order to ascertain the compatibility of Bio Science Keto Gummies with their existing medical regimen. Individuals under the age of 18, pregnant women as well as those nursing a baby ought to refrain from using the gummies without consulting their physician first.

Furthermore, consumers purchase this item from an authorised dealer of Bio Science Keto Gummies to get the best quality product and avoid harm. The ingredients list of the product and its label should be read carefully before usage. This is done to check for allergens or additives that could cause an adverse reaction. If you encounter severe or persistent side effects while taking Bio Science Keto Gummies, discontinue use, and seek medical care immediately. At every stage of product intake, your health is the most essential factor.

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