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A 61-year-old man with diabetes, heart failure (EF 25–30%), obesity, and CKD—how do you decide the next step in therapy? In this powerful episode of Case by Case, three expert clinicians dissect a post-hospitalization case involving a patient with multiple overlapping chronic conditions: Type 2 diabetes, HFrEF, obesity, and impaired renal function. The team weighs the benefits and limitations of SGLT2 inhibitors vs. GLP-1 receptor agonists—and the nuances of when to use both. 🎙️ Topics covered include: • Dapagliflozin in heart failure with reduced EF • Semaglutide and emerging data from the FLOW trial • GLP-1 risks in HFrEF: What the evidence (and gaps) suggest • Clinical nuance: when A1C is good but the patient still needs help • How to argue your case with payers using evidence-based trials 🎓 Meet the Experts: • Dr. Marie E. McDonnell (Harvard / Brigham), Endocrinologist and outcomes researcher focused on complex diabetes care. • Dr. Jan N. Basile (MUSC), Clinical hypertension and primary care expert with decades of CME leadership. • Dr. Nihar R. Desai (Yale), Cardiologist and health systems leader pioneering value-driven care. 💬 “It’s not about A1C—it’s about total disease control: renal preservation, CV death, and survival.” 🔗 Register to claim CME for this panel discussion plus more: https://www.cmemeeting.org/online-cme-courses/10th-diabetes-spring-conference 👍 Like, comment, and subscribe for more expert-level clinical cases each episode.

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