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Merck just signed a $2 billion deal with China’s Hansoh Pharma for an experimental weight-loss pill targeting the booming obesity drug market, projected to hit $100 billion annually by the 2030s. This GLP-1-based drug aims to compete with blockbuster injections like Novo Nordisk’s Wegovy and Eli Lilly’s Mounjaro. Merck’s move could expand beyond weight loss to tackle diabetes, cardiovascular issues, and fatty liver disease. The race for innovative obesity treatments is heating up!
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There has been a lot of buzz recently about the use of semaglutide, a medication typically used to treat type 2 diabetes, for weight loss. One common question that has arisen is whether it is possible to take semaglutide every other week for weight loss, rather than the traditional once-weekly dosing regimen. In this article, we will explore this question in detail, looking at the potential benefits and drawbacks of such an approach.
How Does Semaglutide Work for Weight Loss?
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that works by mimicking the effects of a hormone called incretin. Incretin helps to regulate blood sugar levels by stimulating insulin release and reducing glucagon secretion. In addition to its effects on blood sugar, semaglutide has been shown to reduce appetite and food intake, leading to weight loss in some individuals.
When used for weight loss, semaglutide is typically injected once weekly at a dose of 2.4mg. The medication is believed to work by affecting the appetite control centers in the brain, leading to reduced hunger and increased feelings of fullness. This can help individuals eat less and lose weight over time.
In clinical trials, semaglutide has been shown to be effective for weight loss in overweight and obese individuals. Some studies have reported weight loss of up to 15% of body weight in participants taking semaglutide, compared to placebo. This has led to excitement about the potential of semaglutide as a treatment for obesity.
Potential Benefits of Taking Semaglutide Every Other Week for Weight Loss
One potential benefit of taking semaglutide every other week for weight loss is increased convenience. While the current dosing regimen requires a weekly injection, some individuals may find it easier to remember to take a medication every other week. This could potentially lead to better adherence to treatment and improved weight loss outcomes.
Another potential benefit of taking semaglutide every other week is reduced side effects. Some individuals may experience gastrointestinal side effects such as nausea, vomiting, or diarrhea when taking semaglutide. By reducing the frequency of injections, individuals may experience fewer side effects and have a more positive experience with the medication.
Additionally, some individuals may find it more cost-effective to take semaglutide every other week for weight loss. By reducing the number of injections needed, individuals may be able to save money on medication and administration costs. This could make semaglutide more accessible to a wider range of individuals seeking treatment for obesity.
Drawbacks of Taking Semaglutide Every Other Week for Weight Loss
Despite the potential benefits, there are also some drawbacks to consider when it comes to taking semaglutide every other week for weight loss. One concern is that reducing the frequency of injections could potentially lead to lower effectiveness of the medication. Studies have shown that consistent dosing is important for achieving optimal weight loss outcomes with semaglutide.

Another drawback of taking semaglutide every other week is the potential for fluctuations in blood sugar levels. Semaglutide is known to help regulate blood sugar levels, and reducing the frequency of injections could disrupt this balance. Individuals with diabetes or other conditions that require careful blood sugar monitoring may need to be extra cautious when adjusting their dosing schedule.
Finally, there is limited research on the safety and efficacy of taking semaglutide every other week for weight loss. Most clinical trials have focused on the once-weekly dosing regimen, so it is important to proceed with caution when considering alternative dosing schedules. Individuals should consult with their healthcare provider before making any changes to their medication regimen.
Conclusion
In conclusion, while taking semaglutide every other week for weight loss may offer some benefits in terms of convenience and cost-effectiveness, there are also potential drawbacks to consider. It is important for individuals to discuss any changes to their medication regimen with their healthcare provider to ensure the safety and effectiveness of treatment. Further research is needed to fully understand the implications of alternative dosing schedules for semaglutide and its use in weight loss management.
Overall, semaglutide shows promise as a treatment for obesity, but more research is needed to determine the best dosing regimen for optimal weight loss outcomes.
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To Watch Professor Lustig’s full video, please click here: https://youtu.be/VBnE3KYWqSc Professor Lustig a pediatric endocrinologist and expert on the metabolic impacts of sugar, discussed the profound effects of fructose and other environmental factors on obesity. He emphasized that a gram of fructose causes more weight gain and fat deposition than a gram of any other substance, including fat itself. Dr. Lustig presented two prevailing models of obesity: the energy balance model and the carbohydrate-insulin model. He argued that neither fully explains the obesity epidemic, especially given the increase in obesity among infants who do not diet or exercise. Dr. Lustig introduced the concept of obesogens. A group of chemicals that disrupt endocrine function and promote fat storage. He highlighted the significant impact of these chemicals, particularly on mitochondrial function, and how they contribute to obesity. He presented the "Redux model," suggesting that reactive oxygen species (ROS) generated by these obesogens and certain foods like fructose lead to increased fat storage and infact Fructose is natural obesogen. He stressed the importance of addressing fructose consumption, which can be controlled by eliminating high fructose content from processed foods. Dr. Lustig's presentation underscored the complexity of obesity, influenced by diet, environmental chemicals, and genetic factors, and called for a comprehensive approach to prevention, starting with reducing sugar intake. Be sure to check Emery’s other videos relating to health on this YouTube channel: https://www.youtube.com/playlist?list=PLlTSLi3qD78edU0aWyV8x9yLMIS-FC2fv PLEASE Don't forget to subscribe! IMPORTANT KEYWORDS IN THIS PRESENTATION: Fructose - Mentioned as causing more weight gain and fat deposition compared to other nutrients. Obesity - The central topic, discussed extensively in terms of causes, models, and prevention. Metabolic - Related to metabolic impacts, metabolic syndrome, and metabolic diseases. Sugar - Focused on its effects on health, particularly in processed foods. Diet - The role of diet in health and obesity, including dietary models and recommendations. Insulin - Discussed in the context of the carbohydrate-insulin model of obesity. Oxidative Stress - Related to reactive oxygen species (ROS) and their role in metabolism and obesity. Mitochondria - Highlighted as a crucial aspect of energy metabolism and a target of obesogens. Obesogens - Chemicals that contribute to obesity, discussed in terms of environmental exposure. Nutrition - Broad discussions on nutritional factors influencing health and disease, especially related to obesity and metabolism. #ObesityEpidemic #ChildhoodObesity #MetabolicHealth #SugarReduction #FructoseImpact #HealthEducation #DietMatters #PublicHealth #EnvironmentalObesogens #EndocrineDisruptors #SugarAddiction #HealthyLiving #PreventativeHealth #metabolicdisorders #NutritionScience #MitochondrialFunction About Emery Pharma: Emery Pharma is deeply committed to advancing public health and exclusively focuses on projects that enhance the well-being of both individuals and the environment. As a comprehensive contract research laboratory, Emery Pharma provides extensive support across the entire spectrum of pharmaceutical development, covering small molecule drugs, biologics, biosimilars, gene therapy, botanicals, and more. Emery Pharma's array of premium services includes analytical and bioanalytical solutions, microbiology and cell biology services, drug and impurity characterization, and comprehensive R&D with cGMP/GLP support. The Emery Pharma team excels in customizing innovative solutions tailored to the unique requirements of each client. They seamlessly oversee the entire process, from initial drug discovery to thorough data analysis and insights generation. Their expertise allows them to tackle scientific challenges proactively, ensuring clients avoid unnecessary setbacks. Emery Pharma's accomplished chemists and biologists harness state-of-the-art technology, encompassing cutting-edge tools such as high-resolution mass spectrometry (Orbitrap), triple quad LC-MS/MS, GC-MS, preparative HPLC, and 400 MHz multinuclear NMR. For further details, please don't hesitate to reach out to Emery Pharma at [email protected] or explore their website at: https://emerypharma.com/
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Drinking water can cause weight gain in the short term if the water is retained in the body, known as water retention. This can happen when the kidneys are unable to properly excrete excess water and electrolytes, causing them to be retained in the body. This can lead to a temporary increase in weight on the scale. However, this is not true weight gain and the weight will be lost once the body is able to properly excrete the retained water
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