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Obese Fat Loss Journey Starting at almost 400lbs: Getting fit and losing fat starting at 380lbs is no easy task. It’s hard work, both physically and mentally. In this video, I’m reacting to a very obese man (Devrin Bradford) who kicked off his weight loss journey at 380lbs and is vlogging his journey and has already dropped 50lbs down. It’s inspiring, but I break down what he’s doing well, where he’s struggling, and what could take him further. If you’re on a similar journey or just need some straight-up blunt advice, I’ve got many tips to help you keep going when it feels like the odds are stacked against you. Let me know what you think of his weight loss journey. Devrin Bradford Weight Loss Journey: https://www.youtube.com/watch?v=OeucrlQembk ⚡︎12 Week Online Coaching: https://www.fitnesswithtj.co.uk/start-today/ ⚡︎Personalised Training Plans: http://bit.ly/tjfitnessplan ⚡︎Complete Fat Loss Guide: http://bit.ly/tjfatlossguide ⚡︎How Lose Skinny Fat Body Guide: http://bit.ly/skinnyfatguide ⚡︎FREE Calorie & Macros Guide: https://www.fitnesswithtj.co.uk/help/ ⚡︎Free Ab Workout Routines: https://www.fitnesswithtj.co.uk/help/ Instagram DM me at: http://www.instagram.com/chillinwithtj 0:00 - Getting Fit Starting at 380lbs 1:55 - Why you SHOULD avoid skipping... 4:20 - Importance of mastering your bodyweight 6:30 - How much calories to eat? 7:20 - How long and often should you train? 7:50 - How to avoid mistakes that make you quit! 8:10 - A wise underrated tip to gain results 10:20 - Dealing with negative thoughts... 12:00 - What true gym people think about fat people in the gym 13:30 - Fat Loss Results 14:00 - The importance of cooking at home 16:40 - You dont have to eat chicken broccoli and rice! 17:49 - Why you NEED a boy/girlfriend that supports you! 18:30 - Why consistency trumps... minor diet slip ups 20:00 - Weight loss metrics and videos 20:30 - Why mens have really huge belly's 21:00 - How to lose belly fat 21:00 - Critiquing his physique and results MyProtein 37% Discount: Use link + code to claim discount: https://prf.hn/l/6qOGxEV + Code: TJGAINS BoohooMan: http://bit.ly/tjboohoo Main Topics: #weightlosstips #fatlossjourney #fitness #fatlosstips #fitnesslifestyle #weightlossdiet #weightlossjourney #weightlossdiet #weightlosstransformation Other titles: This Fat Guy Started at 380LBS... (how to succeed or FAIL) Getting FIT Starting at 380LBS... Starting A Weight Loss Journey At 380LBS... (how to succeed or FAIL) How to Go From 380lbs to Fit Without Failing This 380lbs Man Has Lost 50lbs... But Can He KEEP Losing the Weight? I upload uk full day of eating videos, meal prep videos, gym tips, food challenges and of course daily fitness vlogs. Youtube Channels I watch occasionally are greg doucette, christian guzman, chris jones of pumpchasers, merijn from student aesthetics, my boy glen gillen & gabriel sey, mike diamonds, also rob lipsett and some of the other alphalete crew like shawley coker and russ swole! It all depends on my mood and how much cardio i have to do :P ohh and my fave thing to watch at the moment is the joe budden podcast!! My Popular Youtube Playlists: UK Full Day of Eating: https://www.youtube.com/playlist?list=PLU3Jpv4wV2J5vHMgrZCumg2A0PqiqIXcE Bodybuilding Food Shopping: https://www.youtube.com/playlist?list=PLU3Jpv4wV2J7PxuWTRTcFiX8GETMajX0t Facebook: https://www.facebook.com/PureMuscleGains ***** Always consult your physician before beginning any exercise or weight-loss program.

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WrightWatch as Lizzo captivates the Oscars with a jaw-dropping reveal of her dramatic weight loss on a sparkling date with Myke Wright. Her inspiring transformation blends glamour with raw authenticity, turning heads on the red carpet and igniting conversations across Hollywood. This unforgettable moment celebrates confidence, reinvention, and the power of change—an absolute must-see for fans and trendsetters alike! Lizzo Stuns at Oscars: Dramatic Transformation on Date with Myke Lizzo transformation, Oscars weight loss, Myke Wright date, dramatic transformation, Hollywood transformation, celebrity weight loss, red carpet moment, inspiring change, beauty transformation, Oscar moment#lizzo , #Oscars2025, #Transformation, #WeightLoss, #MykeWright, #Hollywood, #Celebrity, #Inspiration, #RedCarpet, #BreakthroughLizzo transformation, Oscars weight loss, Myke Wright, dramatic weight loss, celebrity transformation, Hollywood event, red carpet, inspiring change, beauty transformation, celebrity style, Oscar night, dramatic reveal, celebrity news, trending, inspiring celebrity, weight loss journey, transformation story, music star, entertainment news, viral moment, fashion change, award show, style evolution, bold look, breakthrough moment, celebrity health, motivational, stunning look, new chapterCopyright Owner: Academy of Motion Picture Arts and Sciences (AMPAS). Visit https://www.oscars.org/ and subscribe to https://www.youtube.com/user/oscars.

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TIMESTAMPS BELOW - LIVE TUESDAY JUNE 24, 2025 @ 7 pm (EST) - 4 pm (PST) Austin @Parabolic_33 joins Ryan Root, Jaye, and Erick to discuss the mechanism of action with so-called fat burners. When in a calorie deficit at very low BF% our body tends to hold on to its remaining fat stores. Which is a high risk of losing lean muscle mass. With the proper calorie deficit and the application of "fat burners" you are able to still maintain or even grow new contractile tissue while on a deep cut. This will be a deep dive discussion and Open Q&A Live Stream with Austin, Ryan Root, and Jaye. #testosterone #menshealth #hormones #health #fitness #bodybuiding __________ TIMESTAMPS: 00:00 - Intro 02:08 - Opening remarks, Austin joins the H4M team. 06:50 - Jaye talks about his latest research 17:18 - Gene testing update 18:44 - what do people in new York do for lab work 26:06 - Austin's latest bulk left him with terrible gyno. 31:36 - Austin's client confirms his gyno recovery protocol worked for him. 34:14 - The gyno protocol 41:24 - Does increasing DHT lower prolactin? 42:54 - Looking at Austin's 9 week diet pics and discussing his cut. 52:24 - Fasting 55:52 - Pic of Austin losing muscle from too deep of a cut. 1:00:40 - L-Carnitine 1:02:50 - Mitochondrial optimization 1:07:28 - Austin, regarding stims, I'd way rather use caffeinne every day, because I get so much out of it, but I worry about it losing potency quickly. What are your thoughts on tolerance build up overtime? 1:11:18 - Clenbuterol 1:21:00 - Albuterol 1:24:38 - Adderall and amphetamines. 1:28:05 - Thyroid 1:35:01 - Insulin 1:38:00 - Glp-1's discussion 1:45:00 - Taking insulin and training fasted to raise glucagon. 1:51:10 - NNMT inhibition (e.g., via 5-amino-1MQ) 1:57:12 - HGH 2:03:09 - Bench press talk 2:10:15 - 15% BF and cutting with Reta. 250 test, 250 primo, 4IU HGH. 12 weeks from vacation. How should I dose the Clen and Anavar? When to implement each? 2:13:44 - Austin - was your DHT cream DMSO based? People should be wary of UGL DHT cream sources, many can burn due to DMSO solvent use. 2:16:42 - DSMO, sublingual routes of administration for orals. 2:22:01 - How is your sexual function without DHT in the mix? 2:24:00 - Why would Austin recommend DHB with exogenous E2? 2:34:45 - DHB causes ggt spikes out of range. 2:39:35 - Would micro dosing high potency PIP causing compounds prevent the PIP? 2:45:50 - Hey Austin, how is your client doing, who suffered from aromatase inhibitors and started with estradiol valerate + primo? 2:48:31 - How much testosterone would help with reducing muscle loss on a cut? 2:51:05 - What would be the best fat burner without the negative dopamine effects like GLP-1s give? 2:53:26 - Austin, what fat loss compounds did you use on this cut (glp, slu, cardarine, etc.) ? 2:54:40 - Would adding in Masteron on that type of cycle act as a SERM and keep the gyno away without crushing systemic Estradiol? 2:56:33 - Anyone using mirabegron: when do you take it? I tried it at night to prevent night urination, but I noticed it woke up me up middle of niight b/c of HR increase. 2:59:26 - ENDSCREEN __________ Utilize my TRT/HRT Clinic: https://hormonesforme.com/ Linktree - https://linktr.ee/ryanroot3 FB Group - Ryan Root: https://www.facebook.com/groups/homonesforme Discord - https://discord.com/invite/5GDussZpFp __________ * INTERESTED IN JOINING THE DISCUSSION AS A GUEST? * Contact: [email protected] __________ **Check out Jaye's new YouTube channel: https://www.youtube.com/@Jaye-RDC Parabolic-33 Social's: **YouTube: Parabolic33 https://www.youtube.com/@Parabolic33 **IG: https://www.instagram.com/parabolic_33/ **Join this channel to get access to perks: https://www.youtube.com/channel/UCXTG9HbbD2uC1zZwAR9djgQ/join

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GLP-1 MEDICATIONS AND ITS DARK SIDE | GLP 1 JOURNEY IN REVIEW Let's into the complex landscape of GLP-1 receptor agonists, such as Ozempic and Zepbound shedding light on their dual role as revolutionary treatments for diabetes and obesity. While these drugs are celebrated for their effectiveness in managing blood sugar and promoting weight loss, the script also highlights significant issues related to their high costs, lack of accessibility, and increasing off-label use. The narrative explores the ethical questions of who truly benefits from these medications and at what cost, touching on the systemic inequities and safety concerns that complicate their widespread adoption. 💬 Let’s Connect: 📘 Follow us on Facebook page: 👉 https://www.facebook.com/GLP1journeyinreview 📸 Follow us on Instagram: 👉 https://www.instagram.com/lorrieissman ▶️ Subscribe to YouTube channel: 👉 https://www.youtube.com/@Glp1journeyinreview 🔔 Subscribe to "GLP-1 Journey in Review" for more updates, personal experiences, and expert insights on GLP-1 medications! #glp1journeyinreview #glp1medication #meditation #weightloss #healthyliving #weightlossjourney #zepbound #wagovy #trizepatide #semaglutide #downside

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Hello lovelies,I have started a 60 days weight loss challenge. This is the day 16 video and please Watch other days videos too. I'm following my sister's diet plan .she is a dietitian student. She will give me a diet plan that suits my body type. Everyone's body type is different so don't follow this diet plan. Consult a dietician. Dietitian will give you a suitable diet plan. And if you want diet plan please mail this [email protected]

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🚀 Why These Biotech Stocks Could Skyrocket Wall Street sees massive upside potential in two high-growth biotech companies—one pioneering CRISPR gene editing, the other competing in the $100B weight loss drug market. Here’s why they’re on the radar: 1. Viking Therapeutics (VKTX) – Potential 240% Upside 💊 The Opportunity: Weight Loss Drug Race Developing VK2735, a tirzepatide-like (Mounjaro/Zepbound) injectable & pill for obesity Phase 3 trials starting soon (injectable) + Phase 2 pill data due H2 2025 Market potential: $100B+ obesity drug industry – room for multiple winners 📈 Bull Case: ✔️ Early data showed strong weight loss results (similar to Eli Lilly’s blockbusters) ✔️ Wall Street avg. price target: ~$88 (vs. $26 today) ✔️ High short interest – positive trial news could trigger a short squeeze ⚠️ Risks: Clinical trial failures could crash the stock Competition from Eli Lilly, Novo Nordisk, Amgen 2. CRISPR Therapeutics (CRSP) – Potential 84% Upside 🧬 The Opportunity: First-Ever CRISPR Drug Casgevy: FDA-approved gene therapy for sickle cell & beta thalassemia Launching slowly (complex treatment process) but expects "significant" patient growth in 2025 Upcoming catalysts: Phase 1 cholesterol drug data (huge market potential) Phase 1 lipoprotein(a) data (heart disease risk) Oncology & autoimmune updates 📈 Bull Case: ✔️ First-mover in CRISPR – long-term revenue potential ✔️ Avg. price target: ~$110 (vs. ~$60 today) ✔️ Pipeline depth: Multiple high-impact gene therapies in development ⚠️ Risks: Slow Casgevy adoption (expensive, complex treatment) Gene-editing regulatory hurdles 💰 Bottom Line: VKTX: High-risk, high-reward weight loss play – buy before Phase 3 data CRSP: CRISPR pioneer with approved product + pipeline catalysts 📊 Stock Snapshots: VKTX: $26.05 | Market Cap: $3B CRSP: $60.32 | Market Cap: $4.8B #Biotech #CRISPR #WeightLoss #StocksToWatch 💬 Which stock would you bet on? 🔹 Viking (240% upside potential) 🔹 CRISPR (84% upside + lower risk) 🔔 Subscribe for more high-growth stock picks! 🧪📈 Thanks for watching! If you're new here, make sure to subscribe and turn on notifications so you don't miss any of our future videos. If you're interested in learning more about crypto, finance, and gaming, make sure to check out our website, https://www.patreon.com/c/NexusFinance . We offer a wide range of resources and tools to help you navigate the complex and ever-evolving world of crypto and finance, as well as the latest news and insights on the world of crypto gaming. And if you want to support our work and gain access to exclusive benefits, make sure to check out our Patreon page: https://www.patreon.com/c/NexusFinance Here are some other links that you might find useful: Use this unique invitation link to sign up for Trade Republic and receive a bonus, and start letting your money work for you: https://ref.trade.re/x0gpnjw2 Safeguard Your Crypto w/ a HardWare Wallet: https://amzn.to/3hnThBw Join Womplay and earn NFTs: https://womplay.io/?ref=A7G6TBE Disclaimers: Past Performance Is Not indicative of Future Results: There are no guarantees that it will continue to perform similarly in the future. Market conditions, economic factors, and company-specific risks can all impact returns. Not Financial Advice: This content is for informational purposes only and should not be construed as personalized investment advice. Always consult with a licensed financial advisor before making investment decisions.

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Understanding GLP-1: The Science Behind the Treatment

Glucagon-like peptide-1 (GLP-1) is a hormone that plays a crucial role in the regulation of appetite and glucose metabolism. It is secreted by the intestinal L-cells in response to food intake and promotes insulin secretion while inhibiting glucagon release, which altogether helps to lower blood sugar levels. Additionally, GLP-1 slows gastric emptying and promotes the sensation of fullness, making it a pivotal focus in the quest for effective weight loss solutions. Historically, GLP-1 receptor agonists have been delivered through injections; however, recent advances have opened the door to oral alternative formulations, enabling patients to engage in weight management strategies more comfortably.

The rise of obesity as a global health crisis has positioned GLP-1 modulation at the forefront of medical research and development. Obesity is not merely a cosmetic concern; it is associated with a plethora of comorbidities, including type 2 diabetes, cardiovascular diseases, and certain types of cancer. As such, innovative approaches to weight loss are needed to combat this epidemic. The emergence of GLP-1 pills as oral alternatives to injectable therapies represents a significant breakthrough, allowing for easier administration, improved adherence to treatment regimens, and ultimately, better patient outcomes.

By targeting specific receptors in the body, GLP-1 pills aim to mimic the function of natural GLP-1, offering a host of benefits beyond weight loss, such as improved blood sugar control and reduced risk of diabetes-related complications. As the pharmaceutical landscape rapidly evolves, understanding the mechanisms, benefits, potential side effects, and the holistic impacts of GLP-1 pills are essential for healthcare providers and patients alike. This comprehension will contribute to informed decision-making and encourage a proactive approach to health management.

The Benefits of Oral GLP-1 Medications

The primary advantage of oral GLP-1 medications is convenience. Traditional GLP-1 therapies often require injections, which can be intimidating and inconvenient for many individuals. With oral formulations, patients can administer their medication easily, potentially increasing adherence to weight-loss protocols. The simplicity of taking a pill rather than using a syringe eliminates barriers associated with the fear of needles, transportation of supplies, and the need for proper disposal methods. This ease of use may significantly enhance patient acceptance and, consequently, the overall effectiveness of the weight management strategy.

Moreover, oral GLP-1 medications provide more consistent and prolonged action in the body. They are designed to be absorbed in the gastrointestinal tract and released gradually, ensuring sustained effects on appetite regulation. This approach helps maintain balanced blood sugar levels over an extended period, reducing the fluctuations that can trigger cravings and compulsive eating. Patients often find that the feeling of satiety lasts longer, making it easier to adhere to a reduced-calorie diet essential for weight loss.

Lastly, oral GLP-1 pills may also present fewer gastrointestinal side effects compared to their injectable counterparts. While some individuals using injectable GLP-1 may experience nausea and vomiting, oral formulations can be less irritating to the digestive system. This difference in tolerability can lead to higher acceptance and compliance rates among patients, driving better results in their weight-loss journeys. As with all medications, however, it is crucial for patients to discuss potential side effects with their healthcare providers to ensure a suitable treatment plan.

Mechanisms of Action: How GLP-1 Pills Aid Weight Loss

GLP-1 pills function through a multifaceted approach to achieve effective weight loss. Firstly, they enhance satiety by acting on specific receptors in the hypothalamus, the part of the brain responsible for regulating hunger and fullness signals. When these receptors are activated, patients often experience a decreased desire to eat, leading to reduced calorie intake. This appetite-suppressing characteristic is one of the prime reasons why individuals using GLP-1 medications tend to lose weight effectively over time.

Additionally, these medications slow gastric emptying, which means food moves slower from the stomach into the intestines. This delay prolongs the feeling of fullness and helps control postprandial blood sugar spikes. The regulation of blood sugar levels is particularly important for individuals with obesity, as maintaining stable glucose levels can help prevent cravings and binge-eating behaviors associated with fluctuating blood sugar. Consequently, the combined effects of appetite regulation and blood sugar management effectively create a foundation for sustainable weight loss.

Lastly, GLP-1 pills may influence fat storage and metabolism. Studies indicate that GLP-1 can alter the body’s energy balance by promoting the metabolism of fat rather than its storage, encouraging weight loss even during calorie-restricted diet plans. By shifting the body’s focus from storing excess energy, the use of GLP-1 medications may provide an additional layer of support in the battle against obesity, addressing not only the symptoms but also the underlying mechanisms contributing to weight gain.

Potential Side Effects and Considerations

<pWhile the introduction of oral GLP-1 medications represents a significant leap in weight management options, potential side effects and considerations cannot be overlooked. Patients may experience gastrointestinal disturbances, including nausea, diarrhea, and abdominal discomfort, especially upon initiating therapy. Although these symptoms may lessen over time, they can be a major concern for some individuals. Proper guidance from healthcare professionals can help manage these side effects effectively, and consideration of the patient's overall health and preferences remains paramount.

Another aspect to consider is the potential risk of pancreatitis. Some studies have suggested an association between GLP-1 therapies and an increased risk of pancreatitis, leading patients to report symptoms such as severe abdominal pain or digestive issues. While the overall incidence remains relatively low, it’s essential for healthcare providers to conduct thorough assessments before prescribing these medications. Patients with a history of pancreatitis should communicate openly about their condition to ensure a comprehensive treatment strategy.

Furthermore, patients must engage in healthy lifestyle modifications alongside GLP-1 therapy. Relying solely on medication is not a sustainable solution for weight loss. A balanced diet and regular physical activity are critical components that should accompany any pharmacological approach. Educating patients on the principles of healthy eating, portion control, and the importance of physical activity will ensure that the benefits of GLP-1 pills are maximized while promoting enduring lifestyle changes.

Expert Insights on GLP-1 Medications

Experts in the field of endocrinology and obesity medicine laud the introduction of oral GLP-1 medications as a crucial advancement in the ongoing battle against obesity. Many acknowledge that the barriers associated with injectable medications often deter patients from adhering to treatment plans. Oral alternatives can bridge that gap, offering a user-friendly approach that could contribute to wider acceptance and long-term success in weight management.

Furthermore, with ongoing research and trials, experts are optimistic about the potential efficacy of these medications in various populations, including those with obesity-related comorbidities. Studies continue to reveal promising results regarding the safety and effectiveness of GLP-1 pills in diverse demographic settings, further validating their role as a staple in weight management interventions.

Lastly, medical professionals urge patients to consider a holistic approach that encompasses routine check-ups, dietary education, and involvement in weight loss programs or support groups. The collaborative role of healthcare providers is essential in supporting patients in their weight loss journey, ensuring they have access to resources needed for lasting lifestyle changes while employing GLP-1 medications effectively.

Addressing Common Questions and Concerns

As patients explore GLP-1 medications for weight loss, several common questions arise. One primary concern is regarding the sustainability of weight loss using these pills. While GLP-1 medications can assist in weight reduction, experts agree that maintaining weight loss is only achievable through lifestyle changes. As such, patients are encouraged to incorporate regular physical activity and balanced nutrition into their everyday lives to foster long-term success.

Another common inquiry revolves around the cost and accessibility of oral GLP-1 medications. As they gain approval from regulatory bodies and enter mainstream use, many insurance policies are beginning to cover these treatments, making them more accessible to patients. Understanding insurance options and discussing available support programs with healthcare providers can help patients navigate the financial aspects effectively.

Potential patients are also frequently concerned about long-term safety and side effects. While most individuals tolerate GLP-1 medications well, it’s essential to have ongoing discussions with healthcare providers about risks and benefits. Regular monitoring and adjustments to the treatment regimen can minimize adverse effects and ensure the consistent efficacy of the medication over time. Patients are advised to report any unusual symptoms or changes in their health promptly.

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My 2013 weight loss journey using Phentermine 37.5 prescribed by my Dr. Starting weight - 198.5 Current weight - 180.5 Goal weight - 150-145? Thanks for watching!