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While looking over the research on the effect of GLP-1 receptor agonists on alcohol consumption, I stumbled across a recent and _really_ interesting paper on how that class of drugs affects sensation. It's "Glp-1 Receptor Agonists Significantly Impair Taste Function" by Rafa Khan and Richard L. Doty in _Physiology & Behavior_ Vol. 291 (published version at https://www.sciencedirect.com/science/article/abs/pii/S003193842400341X and white paper version at https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4953499 ). Don't necessarily take that title on its face, as the details are super important and incredibly interesting and maybe not as dire as you'd think. And, well, I felt like it would be a good use of my platform to discuss all of this. So that's what we're doing today, talking about this hugely consequential new class of drugs - Wegovy/Ozempic (semaglutide), Mounjaro (tirzepatide, although that's also a GIP), and whatever else is going to be out there - with an eye towards spirits nerdery. First I broadly discuss the history and basic mechanisms of these drugs, with a brief detour into side effects and what I would consider to be "best practices" in using them for weight loss purposes. (N.b., I don't get into treatment for type 2 diabetes and that's another set of concerns, also I am not a doctor and please consult a medical professional for all this etc..) And then I discuss the paper above. And... well, it's complicated. Based on their results I think the main takeaway is that while GLP-1 agonists seem to have very good odds of degrading your sense of taste, there's also pretty good odds that you won't actually notice. 🤷 Extra special thanks to my Different Spirits on Patreon (https://www.patreon.com/differentspirits), who got this video first - Eric Amig Anthony Darcy Bean Jamie Brown Kingsbury bushcraft William Christopher Clematis Rob D Liam Davitt Joe Devine Samuel Dose Stephen Eckert eon Ingmar nine Steve Frazee Ian Gendler Solomon Grundy John Halliday Alex Hurd Trevor Jarrait Jonathan Lestingi Kyaru Ariel Mserious Craig Nielsen Jason Newquist No Thanks Chris Rhodes Randy Rice RumSquirrel Gordon W Zach W

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Christina Aguilera’s recent appearance on This Morning has ignited concern and speculation among fans, as viewers noticed her dramatically slimmer figure. The pop icon’s transformation left many shocked, with social media buzzing about possible weight loss methods or surgery—though Christina has not responded to these rumors. In this video, we take a closer look at the public reaction, discuss potential reasons behind her transformation, and explore why celebrities often face intense scrutiny over their appearance. Join the conversation and share your thoughts below. If you found this update insightful, don’t forget to like and share the video! #ChristinaAguilera #ThisMorning #CelebrityNews #Transformation #PopCulture OUTLINE: 00:00:00 Christina Aguilera's New Look Shocks Fans on This Morning!

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One of the key ways to stay in shape is to exercise doing things you love! I absolutely love playing basketball, so it has helped me maintain a strong physique and healthy athleticism at 52 years old. For more fitness tips and free consultations, check out my website www.atlantis4health.com :). Please leave a like and comment and I'll reply!

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There’s so much confusion around GLP-1 medications. One of the things I hear people talk about a lot is the risk of muscle loss, but the truth is that it doesn’t cause any more muscle loss than normal weight loss would if the individual isn’t focused on healthy lifestyle factors. Healthy diet, proper sleep, resistance training, etc., At Fit4Life Academy we’ve worked with a number of clients who have used GLP-1 medications and successfully improved their lifestyle-related habits as well. As a result, they’ve been able to come off medication, actually BUILD muscle, and be in a much better place from a health and body composition perspective than when they started!

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