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Keto Complete, a weight loss supplement that was featured on Shark Tank, caused quite the fuzz for viewers and investors alike. The ketogenic diet has been trending for some time, with many people claiming it is effective at enabling people to lose excess weight and improve their overall health. Could Keto Complete be a game-changer in the realm of weight loss supplements by making it easier and more convenient to follow a keto diet?
The Shark Tank Pitch
On Shark Tank, makers of Keto Complete explained how users can reach ketosis faster and better than traditional ways through their product. They took note of the special combination of BHB ketones and other natural ingredients widely known to assist ketosis found in Keto Complete. The science behind the item grabbed shark’s attentions as well as its potential to help people who wish to shed off excessive fats.
Despite an encouraging pitch, Sharks were concerned about market potential or scalability of Keto Complete. While ketone diets have seen increasing popularity over recent years, it remains a niche sector when compared with other systems used for weight reduction. Some sharks raised doubts on whether this could generate enough sales numbers over time.
Success Stories and Customer Reviews
Since being aired on Shark Tank, there are many customers who swear by effectiveness of Keto Complete. A noticeable number of customers have shed off remarkable weights after using Keto Complete as recommended which additionally improved their energy levels as well as general state of health Some people even called the pills “miracle” because they make your body start burning fats quickly.
Accordingly, user reviews of keto complete are overwhelmingly positive with most consumers describing it as both convenient and easy to take/use; alongside this line others also stated that they experienced higher level of consistent ketosis while on this supplement than had been possible through nutrition and exercise alone Additionally others appreciated its appetite suppressant capabilities thus helping them maintain focus throughout their weight management journey.
Expert Opinions and Clinical Studies
Despite anecdotal evidence supporting keto complete’s effectiveness, there are some skeptics among experts in nutrition and weight loss. While a few studies have shown that the ingredients in Keto Complete supports ketosis, most of the supplement industry remains unregulated and this continues to create concerns around product purity and efficacy. Nonetheless unless more robust clinical trials are conducted, it is difficult to establish unequivocally if Keto Complete is indeed a game changer in the world of weight loss supplements.
However many users believe that Keto Complete can be an important tool for those people who want to lose weight or improve their health while many experts say the same thing. In addition to exercise and a healthy diet, using Keto Complete could help an individual meet his/her targeted weight quickly than they would have done by dieting and exercising alone; hence talk to your doctor before you embark on the use of any kind of supplement including Keto Complete during your weight loss attempts.
To sum up:
It cannot be overemphasized that the Shark Tank presentation of Keto Complete surely caused a buzz among the audience and investors, with some supporting it while others condemning it. The influence of this product on the weight loss industry is immeasurable, as expected from its proponents and critics. Whether Keto Complete is transformative or not, it has changed how one can think about starting ketogenic diet in new ways. Like any other slimming aid, use Keto Complete with utmost care and doubtfulness and investigate about it before deciding to adopt it within your obesity reduction plan.
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Inhibitors of dipeptidyl peptidase 4 (DPP-4 inhibitors or gliptins) are a class of oral hypoglycemics that block the enzyme dipeptidyl peptidase-4 (DPP-4). They can be used to treat diabetes mellitus type 2. The first agent of the class – sitagliptin – was approved by the FDA in 2006.[1] Glucagon increases blood glucose levels, and DPP-4 inhibitors reduce glucagon and blood glucose levels. The mechanism of DPP-4 inhibitors is to increase incretin levels (GLP-1 and GIP),[2][3][4] which inhibit glucagon release, which in turn increases insulin secretion, decreases gastric emptying, and decreases blood glucose levels. A 2018 meta-analysis found no favorable effect of DPP-4 inhibitors on all-cause mortality, cardiovascular mortality, myocardial infarction or stroke in patients with type 2 diabetes.[5] ExamplesEdit Drugs belonging to this class are: Sitagliptin[6] (FDA approved 2006, marketed by Merck & Co. as Januvia) Vildagliptin[7] (EU approved 2007, marketed in the EU by Novartis as Galvus) Saxagliptin (FDA approved in 2009, marketed as Onglyza) Linagliptin (FDA approved in 2011, marketed as Tradjenta by Eli Lilly and Company and Boehringer Ingelheim)[8] Gemigliptin (approved in Korea in 2012, marketed by LG Life Sciences)[9] Marketed as Zemiglo Anagliptin (approved in Japan in 2012, marketed by Sanwa Kagaku Kenkyusho Co., Ltd. and Kowa Company, Ltd.)[10] Teneligliptin (approved in Japan in 2012[11]) Alogliptin (FDA approved 2013, marketed by Takeda Pharmaceutical Company) Trelagliptin (approved for use in Japan in 2015) Omarigliptin (MK-3102) (approved in Japan in 2015,[12] developed by Merck & Co.; research showed that omarigliptin can be used as once-weekly treatment and generally well-tolerated throughout the base and extension studies[13]) Evogliptin (approved for use in South Korea[14]) Gosogliptin (approved for use in Russia[15]) Dutogliptin (being developed by Phenomix Corporation), Phase III[16] Other chemicals which may inhibit DPP-4 include: Berberine, an alkaloid found in plants of the genus Berberis, inhibits dipeptidyl peptidase-4 which may at least partly explains its antihyperglycemic activity.[17] Adverse effectsEdit In those taking sulphonylureas, there is an increased risk of low blood sugar.[18] Adverse effects, including nasopharyngitis, headache, nausea, heart failure, hypersensitivity and skin reactions. The U.S. Food and Drug Administration (FDA) is warning that the type 2 diabetes medicines like sitagliptin, saxagliptin, linagliptin, and alogliptin may cause joint pain that can be severe and disabling. FDA has added a new Warning and Precaution about this risk to the labels of all medicines in this drug class, called dipeptidyl peptidase-4 (DPP-4) inhibitors.[19] However, studies assessing risk of rheumatoid arthritis among DPP-4 inhibitor users have been inconclusive.[20] A 2014 review found increased risk of heart failure with saxagliptin and alogliptin, prompting the FDA in 2016 to add warnings to the relevant drug labels.[21] A 2018 meta analysis showed that use of DPP-4 inhibitors was associated with a 58% increased risk of developing acute pancreatitis compared with placebo or no treatment.[22] A 2018 observational study suggested an elevated risk of developing inflammatory bowel disease (specifically, ulcerative colitis), reaching a peak after three to four years of use and decreasing after more than four years of use.[23] CancerEdit In response to a report of precancerous changes in the pancreases of rats and organ donors treated with the DPP-4 inhibitor sitagliptin,[24][25] the United States FDA and the European Medicines Agency each undertook independent reviews of all clinical and preclinical data related to the possible association of DPP-4 inhibitors with pancreatic cancer. In a joint letter to the New England Journal of Medicine, the agencies stated that they had not yet reached a final conclusion regarding a possible causative relationship.[26] A 2014 meta-analysis found no evidence for increased pancreatic cancer risk in people treated with DPP-4 inhibitors, but owing to the modest amount of data available, was not able to completely exclude possible risk.[27] Combination drugsEdit Some of the DPP-4 inhibitor drugs have gotten approval from the FDA to be used with metformin concomitantly with additive effect to increase the level of glucagon-like peptide 1 (GLP-1) which also decreases hepatic glucose production.[28]
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How to Lose Weight Without Dieting? ChatGPT said: Losing weight without dieting is possible by making small lifestyle changes. Focus on portion control—eat slowly and stop when full. Drink plenty of water to stay hydrated and reduce hunger. Get enough sleep, as poor rest can lead to weight gain. Move more throughout the day—take the stairs, walk, or stretch. Reduce stress, as it can cause overeating. Eat whole, unprocessed foods and include protein, fiber, and healthy fats to stay full longer. Avoid sugary drinks and snacks. Practice mindful eating by paying attention to what you eat. Stay consistent with these habits, and over time, you’ll see results without following a strict diet. Small, healthy changes make a big difference! #shorts
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