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Master the pharmacology of diabetes treatments with this comprehensive medical lecture. Designed for medical students, pharmacy students, physicians, pharmacists, and nurses, this session covers the mechanisms of action, effects, side effects, and clinical considerations for major classes of anti-diabetic drugs, including sulfonylureas, metformin, TZDs, DPP-4 inhibitors, GLP-1 receptor agonists, SGLT2 inhibitors, and insulin. This in-depth lecture explores critical aspects of diabetes pharmacology, including: [00:14] Sulfonylureas (SUs): [02:26] Mechanism: Stimulating insulin secretion via ATP-sensitive K+ channel blockade. [04:31] Side Effects: Hypoglycemia, weight gain. [08:47] Meglitinides: Similar insulin secretagogue action, different binding site, [09:43] short-acting. [14:16] Metformin (Biguanides): Mechanism: Reducing hepatic glucose production. [22:56] Side Effects: GI disturbances, lactic acidosis risk. [25:25] Thiazolidinediones (TZDs / Glitazones): Mechanism: PPAR gamma agonists, increasing insulin sensitivity. [30:15] Side Effects: Weight gain, edema. Incretin-Based Therapies: [33:09] GLP-1 Physiology: Origin from preproglucagon. [37:04] DPP-4 Inhibitors: Mechanism (increase endogenous GLP-1 levels). [39:25] GLP-1 Receptor Agonists (GLP-1 RAs): Examples (Semaglutide, Liraglutide); [38:57] Side effects (nausea, vomiting). [47:59] SGLT2 Inhibitors: Mechanism: Increasing urinary glucose elimination. [52:26] Side Effects: UTIs, genital infections. [53:07] Alpha-glucosidase Inhibitors: Mechanism: Reducing carbohydrate absorption. [53:57] Side Effects: Flatulence, diarrhea. [54:41] Pramlintide (Amylin Analog): Mechanism (reduces gastric motility & glucagon secretion). [56:24] Bromocriptine: Dopamine receptor agonist used for glucose lowering. [57:26] Insulin: Role in Type 2 Diabetes management. Key Learning Objectives: Understand the mechanisms of action for major classes of anti-diabetic medications. Identify common and significant side effects associated with each drug class. Differentiate between various diabetes drug classes based on their primary targets and effects (e.g., insulin secretagogues, sensitizers, incretin-based, glucose excretion enhancers). Appreciate the pharmacological basis for choosing different therapies in diabetes management. SANTINIKETAN MEDICAL COLLEGE & HOSPITAL Real Classroom Demonstration/Lecture On: PHARMACOLOGY by Dr. Neeladri Majumder (MBBS Batch: 2023-24) Conducted on: 03-04-25

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Hey guys! Today I'm going to be sharing exactly what I ate in a day to lose weight 30 Lbs in 12 weeks! THE HONEST TRUTH ★ FULL RECIPES + CALORIES (on the blog): https://liezljayne.com/what-i-ate-daily-to-lose-30-lbs-in-12-weeks/ ***Part 1 (HOW I LOST 30 LBS IN 12 WEEKS/ my top tips): https://www.youtube.com/watch?v=J_CDcyv8wc8&t=443s MY WEIGHT LOSS FITNESS ROUTINE: https://www.youtube.com/watch?v=l3A7-VKqUzU MY CALORIE HACKS FOR FAST WEIGHT LOSS: https://www.youtube.com/watch?v=JPqrU5UCyFs&t=56s *This is part of a 3 part series on my channel. I'm sharing all the details of how I lost 30 Lbs in 12 weeks! *THE 3RD PART OF THIS SERIES IS STILL COMING SOON! ALSO here are some links to other helpful weight loss videos/ other info I have for you guys (all linked below here..) ★ MY WEIGHT LOSS GUIDE & MEAL PLAN: http://guides.liezljayne.com/guides/ ★ FREE 3 DAY EATING PLAN: http://guides.liezljayne.com/3-day-ea... ★ WEIGHT LOSS MEAL PREP FOR WOMEN (1 WEEK/ 1 HR): https://www.youtube.com/watch?v=U5GP-... ★ WEIGHT LOSS MEAL PLAN VIDEO #1: https://www.youtube.com/watch?v=BXI-c... ★ WEIGHT LOSS MEAL PLAN VIDEO #2: https://www.youtube.com/watch?v=eu-HN... ★ 20 WEIGHT LOSS HACKS EVERY GIRL SHOULD KNOW: https://www.youtube.com/watch?v=TDW-y... ★ HOW TO LOSE WEIGHT FAST: https://www.youtube.com/watch?v=f2Hlr... ★ MY WEIGHT LOSS STORY: https://www.youtube.com/watch?v=1irWm... *This video in NOT sponsored - All opinions are my own. ------------------------------------------------------------------------------- ★ My "WHAT I EAT IN A DAY TO LOSE WEIGHT" Series: What I eat (DAY 1): https://www.youtube.com/watch?v=7chUi... What I eat (DAY 2): https://youtu.be/Gt5rru0KRGY What I eat (DAY 3): https://www.youtube.com/watch?v=q2Km5... What I eat (DAY 4): https://www.youtube.com/watch?v=7JjX_... What I eat (DAY 5): https://www.youtube.com/watch?v=dE10s... What I eat (DAY 6): https://www.youtube.com/watch?v=dXqg1... What I eat (DAY 7): https://www.youtube.com/watch?v=dXqg1... What I eat (MEAL PLAN): https://youtu.be/JhLLf_GAPW4 What I eat (DAY 8): https://www.youtube.com/watch?v=85doO... What I eat (DAY 9): https://youtu.be/Vw9O9N-7FXE What I eat (DAY 10): https://www.youtube.com/watch?v=E92kn... WEIGHT LOSS MEAL PLAN: https://www.youtube.com/watch?v=BXI-c... ---------------------------------------------------------------------- ★ WORKOUTS + FITNESS STUFF: 16 MIN HIIT WORKOUT: https://liezljayne.com/16-minute-work... MY 5 ESSENTIAL ESSENTIAL EXERCISES (FREE EBOOK): https://guides.liezljayne.com/5-essen... BUTT & LEGS WORKOUT AT HOME: https://www.youtube.com/watch?v=rEb2J... Butt & Thighs workout (full length 15 min): https://www.youtube.com/watch?v=Ti_Fz... Abs workout (full length 10 min): https://www.youtube.com/watch?v=LfUPx... Toned Arms workout (full length 8 min): https://www.youtube.com/watch?v=BiFo1... ---------------------------------------------------------------------- ★ My Links: BLOG: http://liezljayne.com/ INSTAGRAM: https://www.instagram.com/liezljayne/ FACEBOOK: https://www.facebook.com/liezljayne.blog TWITTER: https://twitter.com/liezljayne PINTEREST: https://pinterest.com/liezljayne/ ★ Check out my weight-loss guide & meal plan: http://guides.liezljayne.com/guides/ ★ FREE downloads on my blog: http://guides.liezljayne.com/free/ ---------------------------------------------------------------------------------------- ★ FREQUENTLY ASKED QUESTIONS: I'm answering my most asked Questions here: http://guides.liezljayne.com/frequent... ------------------------------------------------------------------------- Thanks so much for watching this video, I really hope you enjoyed it - and I hope that you found it helpful! Subscribe to my channel for more videos! xo DISCLAIMER - Please note that you should be in a healthy state before you decide to follow a new way of eating, or a calorie restricted diet. It’s always advised that you talk to your GP, doctor or health care professional to see if a new way of eating is suitable for your personal health needs and goals. This eating plan is not suitable for men, children, pregnant women, lactating women, or people who are still developing - It is only intended as inspiration for women who are already in a healthy state, and who are trying to lose weight and get into better shape. This way of eating is only intended for short term use. Please take special note that every women, and every person, will have different daily calorie needs for weight-loss - based on their natural body type and build, current weight, height, daily activity level and health goals. This is not a "one size fits all" way of eating. DISCLAIMER - Please note that you should be in a fit and healthy state before you perform these workouts. It is always a good idea to consult with your doctor, medical practitioner or fitness coach to see if a new exercise program is suitable for you and your personal needs. *THIS VIDEO IS NOT SPONSORED - ALL OPINIONS ARE MY OWN