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Join Thrive Market Today to get 30% Off Your First Order AND a Free Gift Worth up to $50! http://ThriveMarket.com/Thomas This is MORE IMPORTANT than EATING LESS for Fat Loss (energy flux)- Thomas DeLauer To lose weight and improve body composition, it may be best to eat more AND move more in order to attain a higher energy flux. This video does contain a paid partnership with a brand that helps to support this channel. It is because of brands like this that we are able to provide the content that we do for free. Please check out the new workout channel, Garage Built Life, here: https://www.youtube.com/channel/UCQPQImPsw74KhO0Zy2-leyA/videos Please Subscribe to my Email Newsletter Here: https://www.thomasdelauer.com/life-optimization-tactics/ Follow More of My Daily Life on Instagram: http://www.Instagram.com/ThomasDeLauer References https://pubmed.ncbi.nlm.nih.gov/10896648/ https://clinicalnutritionespen.com/article/S2405-4577(15)00152-7/fulltext https://academic.oup.com/ajcn/article/103/6/1389/4637455 https://pubmed.ncbi.nlm.nih.gov/7872209/ https://pubmed.ncbi.nlm.nih.gov/7961258/ https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6835968/ https://academic.oup.com/jcem/article/89/7/3573/2844671 https://academic.oup.com/ajcn/article/103/6/1389/4637455 https://www.tandfonline.com/doi/full/10.1586/17446651.2015.1079483 https://academic.oup.com/cardiovascres/article/117/2/613/5813974 https://pubmed.ncbi.nlm.nih.gov/1337012/ https://academic.oup.com/jcem/article/104/10/4481/5531560 https://academic.oup.com/ajcn/article/103/6/1389/4637455 Timestamps ⏱ 0:00 - Eating More to Lose Weight? 1:45 - The Goal - Be at Energy Balance at a Higher Caloric Intake 2:11 - Exercise More & Eat More for Better Body Composition 5:21 - Join Thrive Market Today to get 30% Off Your First Order AND a Free Gift Worth up to $50! 6:25 - Energy Flux Study - Dr. Melby 8:11 - Low Energy Flux vs High Energy Flux 8:57 - Energy Flux Mechanism(s) -~-~~-~~~-~~-~- Please watch: "Costco Diabetes Haul | Best Foods for Diabetics & Insulin Resistance @ Costco" https://www.youtube.com/watch?v=PXwjcvjGxJY -~-~~-~~~-~~-~-
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GLP-1 receptor agonists, including Ozempic, have revolutionized the management of type 2 diabetes and obesity. These medications offer significant benefits in terms of weight loss and cardiovascular health, though they are not without potential side effects.
Mounjaro (tirzepatide) is a novel medication that has recently emerged as a powerful treatment for type 2 diabetes and an effective option for weight loss. Developed by Eli Lilly and Company, Mounjaro is unique because it acts on two receptors—GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). This dual action sets it apart from other GLP-1 receptor agonists like Ozempic (semaglutide), which targets only the GLP-1 receptor.
We will explore Mounjaro's benefits, side effects, and a comparative analysis with Ozempic, highlighting their differences and similarities.
Mounjaro (Tirzepatide)
Mechanism of Action
Mounjaro is a dual GIP and GLP-1 receptor agonist. By activating these two receptors, Mounjaro enhances insulin secretion, suppresses glucagon release, slows gastric emptying, and increases satiety. This dual action results in improved blood glucose control and significant weight loss.
Benefits
Diabetes Management
Blood Sugar Control: Mounjaro has been shown to significantly lower HbA1c levels, a key marker of long-term blood glucose control.
Improved Insulin Sensitivity: It enhances the body's response to insulin, making it more effective at lowering blood glucose levels.
Weight Loss
Significant Weight Reduction: Clinical trials have demonstrated that Mounjaro can lead to substantial weight loss. Patients have reported losing more weight compared to those taking other GLP-1 receptor agonists.
Increased Satiety: By slowing gastric emptying and promoting a feeling of fullness, Mounjaro helps reduce caloric intake.
Side Effects
Gastrointestinal Issues: Common side effects include nausea, vomiting, diarrhea, and constipation. These symptoms are often mild to moderate and tend to decrease over time.
Hypoglycemia: When used with other diabetes medications, particularly insulin or sulfonylureas, there is a risk of low blood sugar.
Pancreatitis: As with other GLP-1 receptor agonists, there is a potential risk of developing pancreatitis.
Weight Loss
Mounjaro: Clinical trials indicate that Mounjaro may lead to greater weight loss compared to Ozempic. The dual receptor mechanism is thought to contribute to this enhanced effect.
Ozempic: While Ozempic is effective in promoting weight loss, it generally results in less weight reduction compared to Mounjaro.
Cardiovascular Benefits
Mounjaro: Preliminary data suggests that Mounjaro may offer cardiovascular benefits, but more research is needed to confirm these effects.
Ozempic: Ozempic has demonstrated significant cardiovascular benefits, reducing the risk of major cardiovascular events such as heart attack and stroke in high-risk patients.
Dosing and Administration
Mounjaro: Administered once a week via subcutaneous injection. The ease of weekly dosing may improve patient adherence.
Ozempic: Also administered once a week via subcutaneous injection, making it convenient for patients.
Side Effect Profile
Mounjaro: Gastrointestinal side effects are common but typically mild to moderate. There is also a risk of hypoglycemia when used with other diabetes medications and a potential risk of pancreatitis.
Ozempic: Similar to Mounjaro, gastrointestinal issues are the most common side effects. There is also a risk of pancreatitis and, in rare cases, thyroid tumors based on animal studies.
Patient Considerations
When choosing between Mounjaro and Ozempic, several factors should be considered:
Efficacy: For patients needing significant HbA1c reduction and substantial weight loss, Mounjaro may offer superior benefits. However, individual responses can vary.
Side Effects: Both medications have similar side effect profiles, primarily involving gastrointestinal issues. Patients should discuss their medical history and potential risks with their healthcare provider.
Cardiovascular Health: Ozempic has established cardiovascular benefits, making it a preferred choice for patients with a high risk of cardiovascular events. Mounjaro’s cardiovascular effects are promising but require further validation.
Conclusion
Mounjaro represents a significant advancement in the treatment of type 2 diabetes and weight management, thanks to its dual action on GIP and GLP-1 receptors. While Ozempic remains a highly effective option with proven cardiovascular benefits, Mounjaro offers a potentially more potent alternative for patients needing significant glycemic control and weight loss.
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Is the Keto Diet Effective for Managing Type 2 Diabetes? In this informative video, we’ll discuss the ketogenic diet and its potential role in managing Type 2 diabetes. With the rising prevalence of diabetes, many people are seeking effective dietary strategies to help control blood sugar levels. We will explore how the ketogenic diet, characterized by low carbohydrates and high fats, may aid in blood sugar management and weight loss for those living with Type 2 diabetes. We’ll examine recent studies that reveal the impact of the ketogenic diet on blood sugar control and medication reduction. Additionally, we will compare it to the carnivore diet, which focuses solely on animal products, to see how both diets approach carbohydrate intake. While both diets may offer benefits, we’ll also discuss their limitations and the importance of personalized dietary choices. Consulting healthcare professionals is essential when considering any dietary changes, especially for diabetes management. Join us as we break down the facts and provide you with a clearer understanding of these dietary options. Don’t forget to subscribe for more informative content on health and nutrition! ⬇️ Subscribe to our channel for more valuable insights. 🔗Subscribe: https://www.youtube.com/@CarnivoreHealthKitchen/?sub_confirmation=1 #KetoDiet #Type2Diabetes #DiabetesManagement #CarnivoreDiet #BloodSugarControl #WeightLoss #LowCarb #Nutrition #HealthTips #DietaryChoices #InsulinSensitivity #HealthyEating #MedicalAdvice #Wellness #FoodScience About Us: Welcome to Carnivore Health Kitchen! Our channel is dedicated to exploring the carnivore diet, providing you with essential information about meat-only meal plans and benefits of this dietary choice. Whether you’re curious about carnivore vs. keto, nutrient deficiencies that can arise, or how a high-protein diet affects your body, you'll find informative content tailored for your journey. We also cover topics like the best meats for carnivore eating, common mistakes, and the long-term health impacts of this lifestyle.
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