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Extreme Weight Loss (originally titled Extreme Makeover: Weight Loss Edition) is a television program from ABC in which individuals volunteer to receive training and lifestyle changes from trainer Chris Powell. The show is slightly based on the original concept of Extreme Makeover, where individuals receive life-changing makeovers. The exception is that this show focuses primarily on participants losing massive amounts of weight over one year and receiving plastic surgery to remove the excess skin from their transformations.

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Curious about weight loss supplements? Can weight loss supplements actually help? Join Dr Lucy and Dr Mary as they dive into the world of evidence-based nutrition. In this episode of the REAL Health and Weight Loss podcast, they break down the claims surrounding matured hop extract (MHE). MHE has popped in zillions of FB groups promising visceral fat loss but is this actually true? 🎧 You can listen to the whole episode 231 of the Real Health and Weight Loss podcast on your favourite podcast platform or The Real Life Medicine YouTube account #shorts

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Nutritionist Dr. Joey Shulman has tips for getting your body to sense change and break a weight-loss plateau.

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incretin effect| incretin effect glp-1| incretin effect explained| incretin effect in diabetes| incretin hormones| incretin based therapy of diabetes ▪ Incretins are a group of metabolic hormones that stimulate a decrease in blood glucose levels. Gastric inhibitory polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are the two primary incretin hormones secreted from the intestine on ingestion of glucose or nutrients to stimulate insulin secretion from pancreatic β cells. The major mechanism of metabolism of the incretins is cleavage by dipeptidyl peptidase 4 (DPP4), an enzyme that is ubiquitously expressed, including in endothelial cells. ▪ Two pharmacological approaches have been taken to enhance the incretin effect in type 2 diabetes. One approach is to administer GLP-1 'analogues' (GLP-1 receptor agonists) that are resistant to cleavage by DPP4. The other approach is to inhibit DPP4 activity. This effectively increases the half-life and therefore the circulating concentrations of the incretins. ▪ In summary, Ingested glucose causes secretion of incretins from GI tract. These ingredients then increase insulin secretion from the pancreas. Anti-diabetic drugs targeting this mechanism are glp1 analogues and dpp4 inhibitors. And in this way, by increasing insulin secretion, the incretins lower blood glucose. Chapters: 0:00 - Insulin Secretion Mechanism 0:42 - Incretin Effect 1:10 - Incretin Hormones 1:26 - Glucagon-like peptide-1 (GLP-1) Hormone 2:19 - Problem in Diabetes 2:35 - GLP-1 analogues and DPP-4 inhibitors 3:24 - Summary of Incretin Effect incretin hormones, incretin effect, incretin effect glp-1, incretin effect explained, incretin effect in diabetes, insulin, diabetes, glucagon like peptide 1, incretin based therapy of diabetes, incretin pathway, incretin and glp-1, glp 1 analogs, dpp4 inhibitors, sitagliptin, vildagliptin, exenatide, liraglutide, oral antidiabetic drugs, mechanism of insulin secretion, insulin secretion, insulin physiology, insulin pharmacology, diabetes mellitus, medicine, pharmacyd by asim ☕ Buy Me A Coffee: https://www.buymeacoffee.com/pharmacyd 💡 Facebook: https://web.facebook.com/pharmacyd0929 For any Queries and Suggestions Email on: [email protected] Disclaimer: "Content is For Informational & Education Purpose Only, Creamed From Various Authentic Books of Pharmacy & Medicine. The Video Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition." A Famous Quote is: "What We Know is a Drop. What We Don't Know is an Ocean".

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Pop icon Christina Aguilera has sparked concern after a recent fan video went viral, showcasing her dramatic weight loss. Fans are speculating if the transformation is due to Ozempic usage or even a rumored facelift. The 43-year-old singer attended an event at Barry’s Bootcamp to celebrate her debut album's 25th anniversary, but attention quickly shifted to her slender frame. Many took to social media to express their opinions, with some defending her natural body fluctuations, while others speculated about her health. Watch now to see the full story.

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