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Dr. Jade Teta interviews Dr. Lauren Fitzgerald, an MD specializing in functional medicine, about the use of Ozempic and other GLP-1 agonists for weight loss. Dr. Fitzgerald shares her personal experience with using these compounds and how they have helped her and her patients achieve significant weight loss. They discuss the history and mechanism of GLP-1 agonists, as well as the potential risks and benefits. Dr. Fitzgerald emphasizes the importance of using low doses and implementing healthy habits alongside the medication for long-term success. Dr. Lauren Fitzgerald discusses the use of semaglutide for weight loss and shares her experience and insights. She emphasizes the importance of lifestyle changes, such as protein intake and weight training, in conjunction with the medication. Dr. Fitzgerald also explains her approach to dosing, starting with a low dose and adjusting based on individual response and weight loss progress. She highlights the benefits of using a compounding pharmacy and provides tips for maintaining weight loss after discontinuing the medication. Keywords: GLP-1 agonists, weight loss, functional medicine, microdosing, safety profile, Ozempic (semaglutide), weight loss, lifestyle changes, protein intake, weight training, dosing, compounding pharmacy, and maintaining weight loss. Dulaglutide (Trulicity®), Exenatide (Byetta®), Exenatide extended-release (Bydureon®), Liraglutide (Victoza®), Lixisenatide (Adlyxin®), Semaglutide injection (Ozempic®), Semaglutide tablets (Rybelsus®) and tirzepatide (Mounjaro®). Takeaways: - GLP-1 agonists, such as Semaglutide (GLP) and Tirzepatide (GIP/GLP), are bioidentical hormones that regulate hunger and insulin sensitivity. - Traditional dosing of GLP-1 agonists can lead to severe appetite suppression and potential side effects like nausea, vomiting, pancreatitis, and gastroparesis. - Microdosing GLP-1 agonists, starting at 0.25 mg, can be a safer and more sustainable approach for weight loss. - Slow and steady weight loss is more likely to be maintained in the long term. - GLP-1 agonists have a good safety profile when used correctly, and concerns about thyroid cancer are not supported by evidence. Semaglutide can be an effective tool for weight loss when combined with lifestyle changes. - Protein intake and weight training are important for maintaining muscle mass during weight loss. - Dosing of semaglutide should be individualized based on the patient's response and weight loss progress. - Using a compounding pharmacy can provide more flexibility in dosing and cost. - Maintaining weight loss requires ongoing lifestyle changes and a gradual reduction in medication dosage. Chapters 00:00 Introduction to GLP-1 Agonists and Functional Medicine 08:59 The Need for Effective Weight Loss Tools 12:38 Understanding GLP-1 Agonists as Bioidentical Hormones 17:24 The Importance of Low Doses and Safety Profile 21:21 Addressing Concerns about Thyroid Cancer 24:56 Introduction to semaglutide for weight loss 29:19 The importance of measuring data and non-negotiables 31:33 Using a compounding pharmacy for semaglutide 34:13 Benefits and success with compounded semaglutide 36:14 Transitioning to trisepatide if needed 40:32 How to work with Dr. Lauren Fitzgerald 42:25 Connect with Dr. Lauren Fitzgerald online Dr Lauren Fitzgerald: FB: @Dr. Lauren Fitz & Club FITz Fitness IG: @drlaurenfitz www.larimarmed.com
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Medical Economics Senior Editor Richard Payerchin and Robert Kushner, MD, professor of medicine and medical education at Northwestern university talking about the latest advancements in treating obesity, and how physicians should approach the drugs making a splash across the industry. Music Credits: Future Medicine by mark woollard - stock.adobe.com (http://stock.adobe.com) Relaxing Lounge by Classy Call me Man - stock.adobe.com (http://stock.adobe.com) COCKTAIL by Mythical Audio - stock.adobe.com (http://stock.adobe.com) Editor's note: Episode timestamps and transcript produced using AI tools. Introduction to new medications (00:00:00) Discussion on understanding the administration and combination of new medications for weight loss and health improvement. Podcast introduction (00:00:20) Host introduces the episode featuring Richard Payerchin andRobert Kushner, MD, discussing obesity treatment advancements. Current status of physicians (00:01:15) Kushner highlights physicians' increasing awareness and adoption of new obesity medications. Effectiveness of new medications (00:02:02) Overview of how new medications improve weight loss and health outcomes compared to previous treatments. Not a cure-all (00:03:38) Kushner clarifies that while effective, these medications are not a complete solution for obesity. Patient questions and concerns (00:05:14) Common patient inquiries about candidacy for new medications and managing side effects. Criteria for candidacy (00:06:45) Discussion on body mass index (BMI) criteria for patients to qualify for obesity medications. Economic factors in treatment (00:08:34) Challenges regarding medication affordability and insurance coverage impacting treatment decisions. Personal experience with medications (00:09:03) Kushner shares his extensive experience prescribing various obesity medications. Treatment regimen approach (00:10:55) Emphasis on addressing obesity as a chronic disease with appropriate treatment strategies. Lifestyle foundation for treatment (00:13:10) Importance of lifestyle changes alongside pharmacotherapy in obesity management. Avoiding counterfeit medications (00:15:40) Discussion on the dangers of counterfeit drugs and the importance of sourcing legitimate medications. Long-term study insights (00:18:30) Insights from a study on semaglutide and its acceptance rate among patients regarding side effects. Future of obesity medications (00:21:18) Predictions on the long-term safety and efficacy of semaglutide based on recent studies. Financial predictions for coverage (00:23:54) Discussion on potential changes in medication coverage and the future of obesity treatment advancements. Introduction to new medications (00:24:36) Discussion on glucagon and amylin medications showing promise in obesity treatment trials. Oral medications development (00:25:10) Anticipation for oral small molecule medications that mimic injectable treatments for obesity. Medicare approvals and cost implications (00:25:42) Medicare's approval of semaglutide for certain patients and the need to reduce medication costs. Future of medication pricing (00:26:29) Expectations for price renegotiation and the potential for generic medications to lower costs. Importance of primary care engagement (00:26:48) Emphasis on primary care physicians' role in managing obesity with new medications and lifestyle changes. Closing remarks (00:27:59) Gratitude expressed for the discussion and the importance of familiarity with obesity treatments.
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Vídeo que explora 4 fatores que dificultam o início e a continuidade do emagrecimento TIMELINE 01:20 – por onde começar a emagrecer? 03:00 – saber sinalizar o metabolismo 08:15 – e depois que perdeu peso mas parou de emagrecer? 09:00 – peso inicial perdido geralmente é água, não gordura 10:20 – manter consistência 11:40 – fases do emagrecimento 14:40 – ter pressa para emagrecer 16:11 – consistência leva a sustentabilidade e rotina 17:40 – se acomodar só como dieta ou apenas com exercício 20:00 – incorporar dieta com exercício ajuda a sair do platô 21:00 – resumindo e concluindo Ana Maria Gomes Pereira – CREMESP 96158 lattes.cnpq.br/5155858834996266 orcid.org/0000-0003-2697-2791 Estevan Matheus Cuvero – CRP 06/72871 Desenvolvimento Web, CEO, confecção de sites e mídias sociais upwebsites.com.br/ Atendimento clinico on-line estevanmatheus.com.br AVISO As informações dos vídeos deste canal NÃO CONSTITUEM NEM SUBSTITUEM CONSULTA MÉDICA, nem orientação nutrológica, nutricional, psicológica, diagnóstica ou terapêutica de qualquer natureza. O conteúdo deste canal tem caráter meramente informativo com objetivo de divulgação científica (Art. 8 da Resolução do CFM 1974/11 - publicidade do Código de Ética Médica). Os profissionais aqui apresentados não estão divulgando seus serviços de saúde ne publicizando endereços/telefones de consultórios ou clínicas de atendimentos (Art.9 da Resolução do CFM 1974/11, alínea 1, ítem E) e não se responsabilizam por quaisquer resultados de saúde (positivos ou negativos) decorrentes de decisões individuais dos expectadores. LINKS VÍDEO: Dificuldade de emagrecer e os 7 fatores de proteínas: https://youtu.be/cn-5bG8dlJQ?si=iSV2KWz3Km_MZeis VÍDEO: Quanto de proteína comer por refeição? https://youtu.be/QbwelkMVujY?si=0FGL7jtT9ManUHSR VÍDEO: Dificuldades de emagrecer – sinalização do metabolismo: https://youtu.be/QZOAVaSpNGY?si=usBkWA2LtJwZcCdO VÍDEO: Músculos protegem de demência? https://youtu.be/GV00Qepurgo?si=fN-LSuV33V9n_NOC VÍDEO: Metabolismo saudável e músculos: https://youtu.be/2aDSiRmbfB4?si=Yulh27cYckNSeCtV VÍDEO: Como escolher o que comer: https://youtu.be/R55WsNO4_rQ?si=K5qQ_JGqlbWrwYHP VÍDEO: Musculação vs aeróbico para perder gordura: https://youtu.be/b278i_KSMlg?si=JMZBsLtUY65q6RFr VÍDEO: Acelerar o metabolismo: https://youtu.be/VFjWei_-ApM?si=Yff56O5eLwPYBVhA VÍDEO: Como corrigir o metabolismo – Parte 1: https://youtu.be/d_QJm_JTfC0?si=W4k4CPdCvQ82HcEy VÍDEO: Como corrigir o metabolismo – Parte 2: https://youtu.be/3cTPGVpPW1s?si=CSYV5u0Z08as-nX- VÍDEO: Como corrigir o metabolismo – Parte 3: https://youtu.be/MwdrHAMokQ8?si=dgreeCL2h3ES7q0d
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