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We return to the topic of the weight loss drug semaglutide, sold under brand names such as Wegovy and Ozempic, this week. We explore who these drugs are suitable for, what to expect when starting this type of therapy, and how they fit into the broader context of health management. Expect to Learn: ✦ The indications and potential candidates for GLP-1 weight loss drugs ✦ Expected results and side effects of semaglutide therapy ✦ The role of diet and exercise in conjunction with GLP-1 drugs ✦ Strategies for maintaining weight loss after discontinuing the medication ✦ The long-term effects and safety considerations of GLP-1 drugs 🔗 Get full show notes: https://optimizemenutrition.com/podcast/antinutrients 🔗 Get EC’s weekly bonus email: https://optimizemenutrition.com/email/ ABOUT THE SHOW The Consistency Project aims to simplify nutrition, health, and well-being by breaking down the concepts and actions we can all take to live fuller, more functional lives. ABOUT US 📍 EC Synkowski is a Certified Nutrition Specialist® (CNS), a Licensed-Dietitian Nutritionist (LDN), and Certified CrossFit Level 4 Coach (CF-L4). She's the founder of OptimizeMe Nutrition and the creator of the #800gChallenge®. 📍 Patrick Cummings is a long-time CrossFitter, writer, and podcaster. ON SOCIAL EC: https://www.instagram.com/optimizemenutrition/ Patrick: https://www.instagram.com/pscummings Full Disclaimer: https://optimizemenutrition.com/disclaimer/ #ConsistencyProject

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http://373it.com/body Losing belly fat first is a definite plus for those who follow the South Beach Diet. After Phase 1, you will find your pants are quite a bit looser ... you may even have to go shopping for new ones! So, how can a diet cause you to lose weight in a certain area?

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Benefits: This workout helps strengthen your abs, enhance core stability, and burn calories effectively. Day 4 is a step toward a stronger, leaner you—let’s do this! 👉 Don’t forget to like, subscribe, and share your Day 4 experience in the comments. Your progress keeps us motivated—let’s keep pushing forward together! 🔥 #GymAtYourHome #Day4 #FatLossChallenge #CoreWorkout #30DayChallenge

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Explore the McDougall Program's battle against semaglutide in a quest for superior health and weight loss. Dr. John McDougall champions the starch-based diet, showcasing its benefits over semaglutide injections for weight loss. This discussion highlights the starch-based diet's ability to enhance health, reduce costs, and protect the environment, contrasting with semaglutide's high expenses and side effects. The McDougall Program vs semaglutide comparison reveals the natural diet's advantage in mitigating diseases like hypertension and diabetes without the negative impacts of semaglutide weight loss methods. 0:00 - Dr McDougall on Semaglutide vs McDougall Program 4:01 - Health Risks of Weight Loss Drugs 9:05 - Weight Loss Drugs Affecting Your Sex Life? 10:06 - Commonalitiles in McDougall Program & Semaglutides 11:26 - Dietary Impact on Health Conditions 12:51 - Do We All Have Hemorrhoids? 21:08 - Is This Going to Help With Climate Change? 25:20 - Is TSA of 2.7 Worrisome? 28:10 - Too much Strain & Diverticulitis 31:21 - Colon Screening & Diet? 40:00 - Avascular necrosis & More! 44:05 - Avoiding Surgery in Hernia 49:37 - Dumping Syndrome & What Can Help? 55:03 - Bleeding Ulcers in Late 20s! 58:38 - Outro & Next in McDougall Program Alcohol mortality CHD, BP: Zhao J, Stockwell T, Naimi T, Churchill S, Clay J, Sherk A. Association Between Daily Alcohol Intake and Risk of All-Cause Mortality: A Systematic Review and Meta-analyses. JAMA Netw Open. 2023 Mar 1;6(3):e236185. doi: 10.1001/jamanetworkopen.2023.6185. Erratum in: JAMA Netw Open. 2023 May 1;6(5):e2315283. PMID: 37000449; PMCID: PMC10066463. Biddinger KJ, Emdin CA, Haas ME, Wang M, Hindy G, Ellinor PT, Kathiresan S, Khera AV, Aragam KG. Association of Habitual Alcohol Intake With Risk of Cardiovascular Disease. JAMA Netw Open. 2022 Mar 1;5(3):e223849. doi: 10.1001/jamanetworkopen.2022.3849. Erratum in: JAMA Netw Open. 2022 Apr 1;5(4):e2212024. PMID: 35333364; PMCID: PMC8956974. Di Federico S, Filippini T, Whelton PK, Cecchini M, Iamandii I, Boriani G, Vinceti M. Alcohol Intake and Blood Pressure Levels: A Dose-Response Meta-Analysis of Nonexperimental Cohort Studies. Hypertension. 2023 Oct;80(10):1961-1969. doi: 10.1161/HYPERTENSIONAHA.123.21224. Epub 2023 Jul 31. PMID: 37522179; PMCID: PMC10510850. References skin cancer: Mahamat-Saleh Y, Cervenka I, Al Rahmoun M, Savoye I, Mancini FR, Trichopoulou A, Boutron-Ruault MC, Kvaskoff M. Mediterranean dietary pattern and skin cancer risk: A prospective cohort study in French women. Am J Clin Nutr. 2019 Oct 1;110(4):993-1002. doi: 10.1093/ajcn/nqz173. PMID: 31380561. References pregnancy: Makarem N, Chau K, Miller EC, Gyamfi-Bannerman C, Tous I, Booker W, Catov JM, Haas DM, Grobman WA, Levine LD, McNeil R, Bairey Merz CN, Reddy U, Wapner RJ, Wong MS, Bello NA. Association of a Mediterranean Diet Pattern With Adverse Pregnancy Outcomes Among US Women. JAMA Netw Open. 2022 Dec 1;5(12):e2248165. doi: 10.1001/jamanetworkopen.2022.48165. PMID: 36547978; PMCID: PMC9857221. Reference - Delivery systems for semaglutides: Alhiary R?, Kesselheim AS?, Gabriele S?, Beall RF?, Tu SS?, Feldman WB?. Patents and regulatory exclusivities on GLP-1 receptor agonists. ? JAMA. 2023;330(7):650-657. doi:10.1001/jama.2023.13872 References adherence: Gasoyan H, Pfoh ER, Schulte R, Le P, Rothberg MB. Early- and later-stage persistence with antiobesity medications: A retrospective cohort study. Obesity (Silver Spring). 2023 Dec 6. doi: 10.1002/oby.23952. Epub ahead of print. PMID: 38053443. Aronne LJ, Sattar N, Horn DB, et al. Continued Treatment With Tirzepatide for Maintenance of Weight Reduction in Adults With Obesity: The SURMOUNT-4 Randomized Clinical Trial. JAMA. 2024;331(1):38–48. A total of 81.0% of participants reported at least 1 treatment-emergent adverse event during the tirzepatide lead-in treatment period, with the most frequent events being gastrointestinal (nausea [35.5%], diarrhea, [21.1%], constipation [20.7%], and vomiting [16.3%]; 👉 Subscribe to our YouTube Channel to Transform Your Health: @themcdougallprogram 👉Learn more about The Dr. McDougall Health & Medical Center: https://www.drmcdougall.com/?utm_source=youtube&utm_medium=youtube_description&utm_campaign=Dr.McDougall_Website 👉 Join the 12-Day McDougall Program - A life-saving online medical program for over 35 years, reversing and healing chronic illness through expert care, education, and whole food, starch-based nutrition: https://www.drmcdougall.com/12-day-program/?utm_source=youtube&utm_medium=youtube_description&utm_campaign=Dr.McDougall_12_Day_Program 👉 For a wealth of free information, visit our website, where you'll find a treasure trove of resources: https://www.drmcdougall.com/?utm_source=youtube&utm_medium=youtube_description&utm_campaign=visit_our_website We're here to assist you! Feel free to reach out to us at [email protected].

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When it comes to managing weight loss, the pharmaceutical industry has made significant progress in recent years with the development of new medications designed to aid in weight reduction. Two drugs that have gained attention in this regard are Tirzepatide and Semaglutide. Both drugs belong to the class of medications known as glucagon-like peptide-1 (GLP-1) receptor agonists, which work by mimicking the action of the natural hormone GLP-1 to regulate blood sugar levels and decrease appetite.

Tirzepatide

Tirzepatide is a newer drug that has shown promising results in clinical trials for weight loss. It is a dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonist, which means it works on two different hormones to help regulate blood sugar levels and decrease appetite. In studies, patients taking Tirzepatide have experienced significant weight loss compared to those taking a placebo, making it a potentially valuable option for individuals struggling to lose weight.

One of the main benefits of Tirzepatide is its convenience for patients. The medication is administered once a week via injection, which can be more appealing to some individuals than daily dosing regimens. Additionally, Tirzepatide has shown promising results in improving other markers of metabolic health, such as reducing A1c levels in patients with diabetes.

However, like any medication, Tirzepatide is not without its drawbacks. Some patients may experience side effects such as nausea, vomiting, or diarrhea, which can be bothersome for some individuals. Additionally, the long-term safety and efficacy of Tirzepatide are still being studied, so more research is needed to fully understand its impact on weight loss and overall health.

Semaglutide

Semaglutide is another GLP-1 receptor agonist that has been approved for the treatment of obesity in certain patients. Like Tirzepatide, Semaglutide works by mimicking the action of GLP-1 to regulate blood sugar levels and decrease appetite. In clinical trials, patients taking Semaglutide have also experienced significant weight loss compared to those taking a placebo, making it a valuable option for individuals looking to shed pounds.

One of the advantages of Semaglutide is its proven track record in weight management. The medication has been studied extensively in numerous clinical trials and has been shown to be effective in helping patients achieve and maintain weight loss over the long term. Additionally, Semaglutide has been associated with improvements in cardiovascular health, making it a valuable option for individuals with obesity and other metabolic conditions.

Despite its benefits, Semaglutide also has potential side effects that may impact some individuals. Common side effects of the medication include nausea, vomiting, and diarrhea, which can be bothersome for some patients. Additionally, Semaglutide is administered once a week via injection, which may be inconvenient for some individuals who prefer daily dosing regimens.

Comparing Tirzepatide and Semaglutide

When comparing Tirzepatide and Semaglutide for weight loss, several factors should be considered. Both medications have shown promise in helping patients achieve significant weight loss, but they have unique characteristics that may make one more suitable for certain individuals than the other. Tirzepatide may be preferable for individuals seeking a once-weekly dosing option and potential improvements in metabolic health, while Semaglutide may be a better choice for those looking for a medication with a proven track record in weight management and cardiovascular health.

Ultimately, the choice between Tirzepatide and Semaglutide will depend on individual factors such as treatment goals, preferences, and potential side effects. Consulting with a healthcare provider can help determine the best medication option for each individual’s unique needs and circumstances. Both drugs show promise in aiding weight loss, and ongoing research will continue to shed light on their long-term safety and efficacy in managing obesity and related conditions.