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Dr. James Hill—a expert on obesity, metabolism, and long-term weight management—joins me this week to unpack the biggest challenges in sustainable fat loss. Dr. Hill has spent decades researching weight control and the factors that determine whether people can keep weight off long-term. We discuss the science behind energy balance, metabolic flexibility, and why long-term weight loss is about more than just diet and exercise. He shares insights from his groundbreaking work with the National Weight Control Registry, the role of GLP-1 medications, and why physical activity is the key to preventing weight regain. We cover: The critical differences between weight loss and weight maintenance Why physical activity is perhaps more important for keeping weight off than losing it The National Weight Control Registry: lessons from long-term weight loss success stories How metabolism, muscle mass, and energy expenditure affect weight regain The role of protein and resistance training in preserving lean mass The impact of GLP-1 medications on weight loss and why most people regain weight after stopping them The psychology of weight maintenance: mindset, self-monitoring, and behavior change If you’ve ever struggled to keep weight off, or you’re interested in the latest research on metabolic health and sustainable weight management, this episode is a must-listen. Who is Dr. James Hill? Dr. James Hill is an internationally recognized expert on obesity, metabolism, and weight management. He is the co-founder of the National Weight Control Registry, the largest ongoing study tracking individuals who have successfully lost weight and kept it off long-term. Dr. Hill has published over 400 scientific articles and has led pioneering research on energy balance, metabolic flexibility, and the role of physical activity in weight maintenance. He is a professor at the University of Alabama at Birmingham and has served as the President of The Obesity Society. His work has been instrumental in shaping modern obesity treatment and prevention strategies. This episode is brought to you by: Puori - Code DRLYON for 20% off sitewide!– https://Puori.com/DRLYON Cozy Earth - Code DRLYON for up to 40% off! – https://cozyearth.com/DRLYON BON CHARGE - Code DRLYON for 15% off! - https://boncharge.com/DRLYON Manukora- Get $25 off the Starter Kit at https://manukora.com/DRLYON Find Dr. James Hill at: International Weight Control Registry https://internationalweightcontrolregistry.org/ Scholars Profile - https://scholars.uab.edu/6698-james-hill Academic Website - https://www.uab.edu/norc/about-us/leadership/executive-committee/james-hill Find me at: Instagram: @drgabriellelyon TikTok: @drgabriellelyon Facebook: facebook.com/doctorgabriellelyon YouTube: youtube.com/@DrGabrielleLyon X: x.com/drgabriellelyon Apply to become a patient - https://drgabriellelyon.com/new-patient-inquiry/ Join my weekly newsletter - https://institute-for-muscle-centric-medicine.ck.page Get my book - https://drgabriellelyon.com/forever-strong/ Forever Strong Summit 2025 - Grab your ticket NOW before we sell out! https://drgabriellelyon.com/forever-strong-summit-2025/ Timestamps: 00:00 - Intro & Forever Strong Summit Announcement 02:21 - Meet Dr. James Hill 04:34 - Why obesity wasn’t always a major concern 08:12 - The truth about energy balance and weight loss 14:42 - Weight loss vs. weight maintenance: why they require different strategies 18:01 - Why food restriction works for weight loss but fails for maintenance 24:04 - The role of dietary protein and resistance training in weight loss 30:17 - How small changes in energy balance lead to big results 35:07 - Why 150 minutes of exercise per week isn’t enough to maintain weight loss 41:55 - Why most people regain weight after stopping GLP-1 medications 48:00 - How metabolic flexibility influences weight control 52:47 - The importance of tracking body composition over time 1:02:00 - Why exercising your metabolism is key to long-term success 1:09:14 - The underestimated role of mindset in weight management 1:18:27 - The future of obesity treatment: personalized approaches Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

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Ingesting the device prior to eating may induce a sensation of satiety, deceiving the brain into believing that it’s time to stop eating. When you eat a large meal, your stomach sends signals to your brain that create a feeling of fullness, which helps you realize it’s time to stop eating. A stomach full of liquid can also send these messages, which is why dieters are often advised to drink a glass of water before eating. MIT engineers have now come up with a new way to take advantage of that phenomenon, using an ingestible capsule that vibrates within the stomach. These vibrations activate the same stretch receptors that sense when the stomach is distended, creating an illusory sense of fullness. https://scitechdaily.com/the-future-of-weight-loss-new-vibrating-pill-developed-by-mit-reduces-food-intake-by-40/

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Following a ketogenic diet requires careful planning and dedication to ensure you are consuming the right balance of fats, proteins, and carbohydrates. One challenge that many people face on a keto diet is finding satisfying and convenient snacks that comply with their dietary restrictions. The emergence of keto gummies has provided a tasty solution for those looking to satisfy their cravings without straying from their low-carb lifestyle.

What are Keto Gummies?

Keto gummies are a type of snack that is specifically designed to be low in carbs and high in healthy fats. They are typically made with ingredients such as gelatin, MCT oil, and natural sweeteners like stevia or erythritol. These gummies offer a convenient way to satisfy your sweet tooth while staying in ketosis.

When following a ketogenic diet, it is important to be mindful of your carb intake to maintain ketosis, a metabolic state where your body burns fat for fuel instead of carbohydrates. Keto gummies are a great option for those looking for a delicious treat without the guilt of consuming high-carb sweets.

One of the key benefits of keto gummies is that they are often made with clean ingredients that support a healthy lifestyle. Many keto gummies are free from artificial flavors, colors, and preservatives, making them a great alternative to traditional candy that is loaded with sugar and additives.

How to Make Keto Gummies

While you can easily find pre-made keto gummies online or in specialty stores, making your own gummies at home allows you to customize the flavor and ingredients to suit your preferences. To make keto gummies at home, you will need a few key ingredients such as gelatin, water, MCT oil, and a natural sweetener like stevia or erythritol.

Start by blooming the gelatin in cold water, then heat the mixture over low heat until the gelatin is fully dissolved. Add in MCT oil and your sweetener of choice, then pour the mixture into silicone molds and refrigerate until set. You can experiment with different flavors by adding in extracts like vanilla, lemon, or raspberry to create a variety of tasty keto gummies.

Homemade keto gummies are a fun and easy way to enjoy a delicious snack while staying on track with your low-carb diet. You can make a batch of gummies ahead of time and store them in the fridge for a quick and satisfying treat whenever cravings strike.

Benefits of Keto Gummies

In addition to being a tasty and convenient snack for those on a keto diet, keto gummies offer a variety of benefits that make them a popular choice among health-conscious individuals. One of the main benefits of keto gummies is their ability to help satisfy cravings for sweets without increasing your carb intake.

Another benefit of keto gummies is that they are typically low in calories and free from artificial ingredients, making them a guilt-free indulgence for those looking to maintain a healthy weight. The high-fat content in keto gummies also provides a satisfying and satiating snack that can help keep you feeling full between meals.

Additionally, the ingredients used in keto gummies, such as MCT oil, have been shown to have potential health benefits, including improved cognitive function and increased energy levels. By including keto gummies in your diet, you can enjoy a delicious treat while reaping the rewards of their nutrient-rich ingredients.

Where to Buy Keto Gummies

If you prefer the convenience of purchasing pre-made keto gummies, there are several options available online and in health food stores. Look for brands that use high-quality ingredients and offer a variety of flavors to suit your taste preferences. Many keto gummies are also gluten-free, dairy-free, and vegan, making them a versatile snack for individuals with dietary restrictions.

When shopping for keto gummies, be sure to check the nutrition label to ensure they fit within your macronutrient goals. Some keto gummies may contain added ingredients like fiber or collagen for added health benefits, so take the time to read the labels and choose a product that aligns with your dietary needs.

Whether you choose to make your own keto gummies at home or purchase them from a store, incorporating these delicious treats into your ketogenic diet can help you stay on track and satisfy your sweet cravings without compromising your health goals.

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