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Research reveals that while these medications can lead to a significant reduction in body weight (up to 15% after 68 weeks of treatment), the weight may be regained if the medication is discontinued without ongoing lifestyle changes. Long-term studies are still ongoing to fully understand the implications of using GLP-1 medications in younger populations and we can’t down play the importance of nutrition, exercise, and movement from activities like sports. ( This doesn’t mean that select populations can’t benefit from novel interventions or advanced therapeutics - it means that exercise & nutrition help to facilitate the best possible outcomes (physically and mentally) for everyone ] If the American academy for pediatrics can roll out GLP1 for 12 year olds, then hopefully we can include a fraction of this investment on basic lifestyle modification and maybe even upgrade the school cafeteria food 🙏🏽 For the full clip along with a discussion of thyroid, women’s health and metabolic adaption— tune into the intentional strength podcast 🎙️ 🎧 Thank You for the support, Sam. 🔔 SUBSCRIBE for more! Listen to our full episodes here → https://open.spotify.com/show/1pOzGDriI0ENoR6PN8CuEg Thank You for the support, Sam. 🔔 SUBSCRIBE for more! My Amazon Best Selling Book on Nutrition and Metabolism: https://metabolismmadesimple.com/ More Free Content, Articles, Workshops and Audio Podcast: https://sammillerscience.com/ My Live Mentorship and Specialization Program for Health, Fitness, and Nutrition Professionals: https://metabolismschool.com/

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Here's a YouTube description based on the provided sources about Eli Lilly's oral GLP-1 drug, orforglipron: --- **Title Suggestion:** Eli Lilly's Oral GLP-1 Breakthrough: Is Orforglipron the Future of Weight Loss & Diabetes Treatment? **Description:** Discover the exciting potential of Eli Lilly's new oral GLP-1 drug, orforglipron, which is poised to revolutionize the treatment of obesity and Type 2 Diabetes! In its first Phase 3 clinical trial, ACHIEVE-1, orforglipron demonstrated remarkable effectiveness, comparable to injectable weight-loss medications. Participants with Type 2 Diabetes achieved significant reductions in blood sugar levels, with HbA1c lowering by an average of 1.3% to 1.6% depending on the dose. Many even reached HbA1c levels below 6.5%, meeting the American Diabetes Association's threshold for diabetes control. But that's not all – this once-daily oral tablet also led to impressive weight loss! Participants lost an average of 7.3 kg (7.9%) at the highest dose over 40 weeks, with researchers noting that weight changes appeared to still be ongoing, suggesting potential for even greater loss with continued treatment. This is particularly promising, as individuals without diabetes might experience even more weight reduction. One of orforglipron's biggest advantages is its user-friendly profile. Unlike other oral GLP-1s like Novo Nordisk's Rybelsus, orforglipron can be taken at any time, regardless of meals or water intake, making adherence much easier for patients. This convenience, combined with its effectiveness, makes it a game-changer, especially for the millions who prefer pills over injections due to needle phobia. While its weight loss benefits are slightly less than Lilly's injectable Zepbound (which showed 15.3% to 36.2% reduction in non-diabetic patients), orforglipron's A1C reduction is comparable to injectable GLP-1s like Ozempic. Its safety profile is consistent with other GLP-1 therapies, with common side effects including diarrhea, nausea, and indigestion. Eli Lilly is confident in orforglipron's market potential and plans to seek approval for obesity treatment later this year, followed by Type 2 Diabetes in 2026. Importantly, the company suggests they could launch orforglipron globally "without supply constraints," offering a crucial solution amid ongoing shortages of injectable GLP-1 drugs. Could this daily pill be the breakthrough we've been waiting for? Watch to learn more! #EliLilly #Orforglipron #GLP1 #WeightLoss #DiabetesTreatment #OralMedication #NewDrug #HealthcareInnovation #Type2Diabetes #ObesityTreatment #Achieve1Trial #MedicalBreakthrough ---Vast Utility For Weight Loss Drugs Will More Than Pay For Themselves Says Eli Lilly Ceo David Ricks

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