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#diabetes #weightloss #diabetesdrug Research Reveals Method to Improve Diabetes and Weight-Loss Drug Performance According to new research from the University of Michigan, a network of proteins found in the central nervous system could be leveraged to enhance the effectiveness and minimize the side effects of popular diabetes and weight-loss medications. The study, published in the Journal of Clinical Investigation, focused on two proteins, melanocortin 3 and melanocortin 4, primarily located on the surface of neurons in the brain. These proteins play a central role in regulating feeding behavior and maintaining the body's energy balance.Melanocortin 3 and 4 influence everything from sensing long-term energy stores to processing gut signals about short-term satiety. GLP-1 agonists, such as semaglutides (e.g., Ozempic) and tirzepatides (e.g., Mounjaro), have gained attention for effectively treating type 2 diabetes, obesity, heart disease, and potentially addiction. These drugs mimic a natural hormone produced by the gut when full, signaling the brain to reduce feeding behavior. In the study, researchers tested the effects of several hormones that reduce food intake in the mouse models and discovered that modifying the melanocortin system made mice more responsive to GLP-1 drugs and other hormones influencing feeding behavior. Mice treated with a combination of a GLP-1 drug and an MC4R agonist or MC3R antagonist experienced up to five times more weight loss and reduced feeding compared to those receiving only GLP-1 drugs. The researchers also measured brain activity in areas associated with nausea from GLP-1 drugs and found no increased activation when these drugs were combined with alterations to the melanocortin system. However, priming melanocortin neurons significantly boosted GLP-1 drug activation in hypothalamic feeding centers. The findings suggested that combining GLP-1 drugs with an MC4R agonist could increase the drugs' effectiveness by up to fivefold without enhancing side effects. This approach could allow patients sensitive to side effects to take lower doses or improve outcomes in those unresponsive to current dosages. Further drug development and clinical testing are needed to advance this strategy. Although this research has only been conducted in mouse models, researchers remain optimistic that the results will translate effectively to humans. "The melanocortin system is highly conserved in humans. Everything we've observed in the mouse over the past decades studying these proteins has also been found in humans, so I suspect that these results would also be translatable to patients,” said Cone, director of the U-M Life Sciences Institute Check full updates on Medical Dialogues Also check out - Medical Dialogues Academy, a renowned academic wing of Medical Dialogues - India's premier health and news online portal, proudly presents this comprehensive course tailored for healthcare professionals eager to delve into the realm of medical journalism. 🔗 Enroll Today: https://academy.medicaldialogues.in/courses/certificate-course-in-medical-journalism/ 📚 Explore More With Us: 📌 Medical Content Writing: https://academy.medicaldialogues.in/courses/medical-content-writing/ 📌 Certificate Course in Pharmaceutical Medico-Marketing: https://academy.medicaldialogues.in/courses/certificate-course-in-pharmaceutical-medico-marketing/ Join us on this enlightening journey and become a part of a community pushing the boundaries of healthcare communication and reporting. Get the latest medical and health news at medicaldialogues.in Follow us on Twitter: https://twitter.com/medicaldialogs Facebook: https://www.facebook.com/medicaldialogues/ Instagram: https://www.instagram.com/medicaldialogues LinkedIn: https://www.linkedin.com/company/medical-dialogues Website: https://medicaldialogues.in/

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Are you on the ketogenic diet and looking for quality supplements to support your lifestyle? Look no further than GNC! GNC is a well-known retailer that offers a wide range of health and wellness products, including keto-friendly options like Keto Gummies. These gummies are a convenient and delicious way to get your daily dose of essential nutrients while staying in ketosis. In this article, we will explore how you can find quality ketogenic supplements at GNC stores.

Why Choose Keto Gummies from GNC?

Keto Gummies from GNC are an excellent choice for those following a ketogenic diet. These gummies are specifically formulated to provide the nutrients your body needs while staying in ketosis. They are made with high-quality ingredients and are free from artificial flavors and colors. Plus, they come in delicious flavors that make them a tasty treat any time of day.

When you choose Keto Gummies from GNC, you can trust that you are getting a reliable product from a reputable retailer. GNC is known for its commitment to quality and transparency in its products, so you can feel confident that you are getting a supplement that meets your needs. Additionally, GNC offers a wide selection of keto-friendly products, so you can easily find the right supplements to support your ketogenic lifestyle.

Another reason to choose Keto Gummies from GNC is convenience. These gummies are easy to take on the go, making it simple to get your daily dose of essential nutrients wherever you are. Whether you’re at work, at the gym, or traveling, you can easily incorporate these gummies into your daily routine. Plus, the delicious flavors make them a delightful treat that you’ll look forward to enjoying.

Finding Quality Ketogenic Supplements at GNC Stores

When it comes to finding quality ketogenic supplements at GNC stores, there are a few things to keep in mind. First, look for products that are specifically formulated for the ketogenic diet. These products will contain the right balance of nutrients to support your body’s needs while staying in ketosis. Additionally, check the ingredient list to ensure that the supplements are free from artificial additives and fillers.

It’s also essential to do your research and read reviews from other customers before making a purchase. This can help you determine the quality and effectiveness of the product you are considering. Look for products that have received positive feedback from customers who have tried them, as this can be a good indicator of their quality.

Lastly, consider talking to a healthcare professional or nutritionist before adding any new supplements to your routine. They can provide guidance on which supplements are best for your individual needs and help you avoid any potential interactions with other medications or health conditions. By taking these steps, you can ensure that you are getting quality ketogenic supplements that support your health and wellness goals.

FAQs About Keto Gummies from GNC

Q: Are Keto Gummies from GNC suitable for all ketogenic dieters?

A: Keto Gummies from GNC are generally suitable for most people following a ketogenic diet. However, it’s essential to check the ingredient list and consult with a healthcare professional before adding any new supplements to your routine.

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Q: How do I know if Keto Gummies are right for me?

A: If you’re looking for a convenient and delicious way to get your daily dose of essential nutrients while staying in ketosis, Keto Gummies from GNC may be right for you. Consider your dietary needs and goals before making a purchase.

Q: Can I find Keto Gummies at all GNC stores?

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A: While Keto Gummies are available at many GNC stores, availability may vary depending on location. Check with your local GNC store or visit their website to see if Keto Gummies are available near you.

Q: How should I incorporate Keto Gummies into my daily routine?

A: Keto Gummies can be taken as a daily supplement to support your ketogenic lifestyle. Follow the recommended dosage on the product label, and consider incorporating them into your daily routine for best results.

Q: Are there any side effects associated with taking Keto Gummies?

A: Most people tolerate Keto Gummies well, but some individuals may experience gastrointestinal discomfort or allergic reactions. If you experience any adverse effects, discontinue use and consult with a healthcare professional.