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GLP-1 drugs like Ozempic have been life-changing for diabetes and weight loss. But could they also reduce the risk of dementia? Hello 👋 I’m Luke, a PhD student at the University of Oxford with a keen interest in evidence-based decision-making, health economics, and clinical research. My goal is to help people better understand the science behind health claims so they can make informed choices. In this video, I break down the latest research — including clinical trials and meta-analyses — to explore whether GLP-1 drugs like semaglutide might help protect the brain. 🔍 What You’ll Learn: ✔️ The link between diabetes and dementia ✔️ What the latest meta-analyses show (GLP-1s, SGLT2is, pioglitazone) ✔️ How to interpret forest plots ✔️ Key limitations of the current evidence ✔️ Upcoming trials and what to look out for 💬 Let me know your thoughts in the comments — especially what you think about the long-term role of GLP-1s in brain health. ⚠️ Disclaimer: This video is for educational purposes only. It is based on publicly available research and my own independent analysis. It is not medical advice. Always consult a qualified healthcare professional before making health decisions. 📖 References: REF1: https://www.alzheimersresearchuk.org/dementia-information/dementia-risk/diabetes-and-dementia-risk/ REF2: https://pubmed.ncbi.nlm.nih.gov/30149446/ REF3: https://pubmed.ncbi.nlm.nih.gov/40193122/ REF4: https://aaic.alz.org/releases-2024/glp-drug-liraglutide-may-protect-against-dementia.asp REF5: https://alzres.biomedcentral.com/articles/10.1186/s13195-024-01666-7

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