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#Misinformation aided and abetted by social media is a growing problem that is harming public #health and putting lives of millions of people at risk. The First Check team of Health Analytics Asia is leading an initiative to identify and combat medical misinformation, #hoaxes, #unscientific medical advice and dubious claims. This video series is aimed to improve the quality of #health and science reporting through video stories by debunking #unscientific myths, medical misinformation and or fake/doctored videos or images related to public health. This initiative is awarded by a grant from International Fact Checking Initiative (IFCN) with support from YouTube. Our approach to build collaboration with doctors is globally recognised as a unique initiative and more recently, we’ve been selected by New York University for the Membership PuzzleProject, a global public research project studying how to optimise news for trust in the 21st century. New episodes every week For more information visit our websites : https://www.ha-asia.com https://www.firstcheck.in Credits: Edited & Produced: Hashim Ahmad Hakeem

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[서울=뉴스핌] 황숙혜 기자 = 당뇨병 환자들의 혈당 조절을 위한 약물의 핵심인 GLP-1이 비만 치료 효과를 앞세워 블록버스터로 부상한 가운데 암 치료 가능성까지 확인되면서 월가의 조명이 집중되고 있습니다. 일라이 릴리를 포함해 비만 치료를 위한 GLP-1 유사체 약물을 공급하는 제약사들이 또 한 차례 성장 모멘텀을 얻을 수 있다는 기대가 관련 업계와 투자자들 사이에 번지고 있는 모양새입니다. 본래 GLP-1은 췌장에 작용해 인슐린 분비를 촉진하고 혈당을 높이는 글루카곤 분비를 억제하는 호르몬입니다. 혈당이 올라갈 때 수치를 낮추는 기전을 가진 GLP-1은 위장 운동을 늦춰 음식물이 장내에 오래 머물도록 하는 한편 뇌의 포만 중추를 자극해 식욕을 억제하는 효과를 가진 것으로 입증되었습니다. GLP-1 유사체를 이용한 비만 치료제가 제조된 배경도 여기에 있습니다. GLP-1과 암의 연관 관계는 2024년부터 본격적으로 제기되었습니다. 호르몬이 체중 감량에 효과를 내는 만큼 비만과 관련성이 높은 암의 발병 위험을 낮추는 데 효과적일 수 있다는 의견이 제기된 것입니다. 대장암과 간암, 신장암, 췌장암, 유방암, 난소암 등 의학계는 10여 가지 암을 비만 관련 암으로 분류하고 있습니다. 최근까지 연구에서 사람들이 체중을 감량할 때 암을 포함한 여러 질병의 발병 위험이 줄어드는 것으로 나타난 데 이어 내분비학회 연례회의에서 발표된 연구에서 GLP-1 작용제가 보다 직접적으로 암세포에 작용한다는 사실이 확인되었습니다. 동물을 이용한 실험에서 GLP-1이 유방암 종양 크기를 축소시키는 것으로 확인되었다고 학회는 발표했습니다. GLP-1이 미국 식품의약청으로부터 항암제로 승인받기까지는 아직 갈 길이 멀지만 최근까지 연구 결과가 암 발생 예방 그리고 더 나아가 암 치료까지 가능성을 열었다는 데 월가는 의미를 두고 있습니다. 실제 항암 치료에 GLP-1이 적용되려면 동물에 이어 환자를 대상으로 수차례의 대규모 임상 시험을 실시해 효능과 안전성을 입증해야 하고, 최근까지 나온 연구 결과를 최종 목적지까지 가기 위한 초기 단계라고 볼 수 있습니다. 장거리 마라톤의 출발 선에서 첫 발을 뗀 상황이지만 시장 전문가들은 낙관적입니다. GLP-1이 단순히 당뇨병 치료 효과를 가져오는 데 그치지 않고 체중 감량과 암 치료 효과까지 기대할 수 있다는 사실만으로도 의미가 작지 않다는 얘기입니다. UBS는 보고서를 내고 GLP-1 의약품 판매 규모가 2023~2029년 사이 연평균 30% 급증하는 시나리오를 제시했습니다. 시장 조사 업체 그랜드 뷰 리서치는 보고서를 통해 북미 지역의 GLP-1 수용체 작용제 의약품 판매 규모가 2023년 280억 달러에서 2030년 1391억 달러로 급팽창할 것으로 내다봤습니다. 2024~2030년 사이 북미 지역에서만 연평균 25.7%의 성장을 기록하는 셈입니다. 일라이 릴리는 이미 시장 성장에 커다란 반사이익을 보고 있습니다. 2025년 1분기 업체의 매출액이 127억 달러로 전년 대비 45% 급증한 가운데 젭바운드와 마운자로의 매출 규모가 총 62억 달러로 절반 이상의 비중을 차지했습니다. 주요 외신에 따르면 일라이 릴리는 하루 한 번 복용하는 알약 형태의 GLP-1 의약품 개발을 위해 3상 임상시험까지 완료했습니다. 미 식품의약청의 승인을 받으면 약품을 당뇨병과 비만 치료용으로 공급한다는 계획입니다. 업체는 3상 임상시험 결과가 고무적이라고 발표했습니다. 오르포글리프론은 저분자 약물로, 오젬픽과 마운자로 등 주사제 형태의 약물에 비해 편의성이 높습니다. 모간 스탠리는 경구용 GLP-1이 게임체인저가 될 것이라며 낙관론을 펼쳤습니다. 오르포글리프론의 미 식약청 승인이 확실시되고, 본격적인 판매가 개시되면 기존 주사제 GLP-1 시장을 급속하게 침투할 것이라는 얘기입니다.

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Andrew Huberman's weight loss diet. I was tagged in this video of Andrew Huberman saying if you want to lose weight, "you can eat meat, fish, eggs, fruits, vegetables... if it is not in that list, you are not eating it". I think this serves as a very useful lesson. What is being described is actually very similar to a paleo (caveman) diet, with the further removal of nuts and seeds. In short, you can ONLY eat meat, fish, eggs, fruits and vegetables. And it *can* work. There are numerous research papers showing that people who follow a paleo diet will often 1) lose weight 2) improve their health markers. And this can happen even when people are NOT given calorie goals. They just naturally consume fewer calories by the prescription of food choice. They are prioritising nutritious foods that are good for appetite regulation (on average) and also eliminating all ultra-processed foods which are worse for appetite regulation (on average). This obviously sounds great. But there is a flip side. This diet has also been criticised for being 1) unnecessarily rigid (especially with the removal of dairy, grains and legumes, let alone STRICT avoidance of everything else) 2) unnecessarily expensive 3) difficult to adhere to in the long term. For example, a mere 4-week feasibility study described it as possibly being impractical for use in clinical and public health settings. So I think this is a good lesson for you which you can apply to any dietary approach you like. Focusing on food quality can be great. But sometimes it goes too far, and if a diet is so strict that is it difficult to stick to long term, it might not be a smart idea for you to follow it. Does that make sense? References: - A paleolithic diet is more satiating per calorie than a mediterranean-like diet in individuals with ischemic heart disease - Influence of Paleolithic diet on anthropometric markers in chronic diseases: systematic review and meta-analysis - The feasibility of a Paleolithic diet for low-income consumer - Experiences of barriers and facilitators to weight-loss in a diet intervention - a qualitative study of women in northern Sweden - Paleolithic nutrition for metabolic syndrome: systematic review and meta-analysis. - Compliance, Palatability and Feasibility of PALEOLITHIC and Australian Guide to Healthy Eating Diets in Healthy Women: A 4-Week Dietary Intervention

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Over the years, the hit TV show Shark Tank has been a platform for entrepreneurs to showcase their innovative products and pitch their businesses to a panel of established investors. Some of the products featured on the show have become household names, while others have faded into obscurity. One product category that made waves on Shark Tank is keto pills. These pills claimed to help individuals achieve ketosis faster, burn fat more efficiently, and boost energy levels.

The Keto Pills That Took Shark Tank by Storm

One of the most memorable pitches on Shark Tank was by a company selling keto pills that promised to revolutionize the way people lose weight. The entrepreneurs behind the product claimed that their pills were backed by science and could help users see significant weight loss results in a short amount of time. The Sharks were intrigued by the potential of the product and several of them made offers to invest in the company.

After the episode aired, the keto pills flew off the shelves and became a trending topic on social media. Many people who watched the show were eager to try the pills for themselves and see if they could achieve similar results. The company saw a massive surge in sales and quickly became a household name in the weight loss industry.

Where Are They Now?

Unfortunately, despite the initial hype and success, the keto pills eventually fell out of favor with consumers. While some users reported seeing positive results from taking the pills, others experienced side effects and minimal weight loss. Soon, questions arose about the effectiveness and safety of the product, leading to a decline in sales and a tarnished reputation for the company.

As more research was conducted on the ingredients and formulation of the keto pills, it became apparent that the product may not have been as revolutionary as initially claimed. Many experts in the weight loss industry criticized the pills for making unrealistic promises and capitalizing on the keto trend without providing substantial evidence to support their claims.

Today, the company behind the keto pills has shifted its focus to other products and aspects of the health and wellness industry. While they may have moved on from the hype of their Shark Tank appearance, the legacy of their keto pills still lingers in the minds of those who were intrigued by the potential of the product. Whether or not they will attempt a comeback with a new and improved formula remains to be seen.

FAQ: The Truth About Keto Pills

Q: Do keto pills really work?

A: The effectiveness of keto pills varies from person to person. Some individuals may see positive results in terms of weight loss and energy levels, while others may not experience any significant changes. It is important to consult with a healthcare professional before starting any new supplement regimen.

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Q: Are keto pills safe to take?

A: The safety of keto pills is a subject of debate among health experts. Some ingredients commonly found in these pills, such as exogenous ketones, have been linked to potential side effects such as digestive issues and electrolyte imbalances. It is crucial to read the label carefully and follow dosage instructions to minimize any risks.

Q: Can keto pills help me lose weight faster?

A: While keto pills may provide a temporary boost in metabolism and fat burning, they are not a magic solution for weight loss. Sustainable weight loss requires a combination of a healthy diet, regular exercise, and lifestyle modifications. It is essential to approach weight loss with a holistic and long-term perspective.

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