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00:00 - Intro 00:13 - GLP-1 RA Weight Loss Drugs: Hidden Ocular Risks Explained | Optic Neuropathy & Retinal Health 03:39 - Ozempic & GLP-1 Drugs: UK Investigation into Deadly Pancreatitis Side Effects 1. GLP-1 RA Weight Loss Drugs: Hidden Ocular Risks Explained | Optic Neuropathy & Retinal Health Discover the potential ocular risks of GLP-1 receptor agonists (GLP-1 RAs) like semaglutide (Ozempic/Wegovy). This video explores studies linking these popular weight loss and diabetes drugs to optic neuropathy, retinal complications, and diabetic retinopathy progression. Learn about the science behind GLP-1 RAs, their mechanisms of action, and how rapid blood glucose/lipid changes may impact eye health. Understand the debate around 'early worsening' effects, microvascular damage theories, and why ophthalmologists recommend baseline eye exams for patients on GLP-1 RA therapy. Key topics include: - Overview of GLP-1 RA drugs and their rise in popularity - Retinal health risks: diabetic retinopathy, vitreous hemorrhage, and NAION - Mixed study results: protective vs. harmful effects on ocular microvascular health - Clinical recommendations for monitoring patients on GLP-1 RAs - Limitations in current research and future directions Whether you're a healthcare professional or a patient considering GLP-1 RA therapy, this video provides critical insights into balancing benefits and risks for ocular safety. 2. Ozempic & GLP-1 Drugs: UK Investigation into Deadly Pancreatitis Side Effects The UK Medicines and Healthcare products Regulatory Agency (MHRA) is investigating serious pancreatitis risks linked to GLP-1 weight-loss drugs like Ozempic and Mounjaro, with reports of acute pancreatitis cases and at least 10 deaths in the UK. This potentially fatal side effect has raised concerns about the safety of these medications, which are prescribed for weight loss and diabetes management. The MHRA’s Yellow Card scheme received nearly 400 reports of pancreas issues, including acute pancreatitis—a condition requiring hospitalization and associated with severe abdominal pain, nausea, and fever. While pharmaceutical companies like Novo Nordisk and Lilly assert their commitment to patient safety, genetic factors may influence susceptibility to such side effects. In the US, though no formal investigation exists, studies indicate a higher risk of pancreatitis among GLP-1 users. The FDA requires warnings about this risk and monitors reports. This video explores the latest developments in this medical crisis and what patients should know.
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Semaglutide is a medication that has recently made headlines for its potential to aid in weight loss. Originally approved for the treatment of type 2 diabetes, semaglutide has shown promising results in helping individuals shed excess pounds as well. This has led many people to seek out where they can buy semaglutide for weight loss purposes.
What is Semaglutide?
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that works by mimicking the effects of a hormone in the body that helps regulate blood sugar levels. Originally developed for the treatment of diabetes, semaglutide has been found to have additional benefits in aiding weight loss. It works by increasing feelings of fullness, reducing hunger, and slowing down the emptying of the stomach, all of which can contribute to weight loss.
Semaglutide comes in the form of a once-weekly injection that can be self-administered. It is usually prescribed as part of a comprehensive weight loss program that includes dietary changes and increased physical activity. While individual results may vary, studies have shown that semaglutide can lead to significant weight loss in many patients.
It is important to note that semaglutide is not a magic weight loss solution and should not be seen as a quick fix. It is most effective when used in conjunction with a healthy lifestyle that includes a balanced diet and regular exercise. It is also important to consult with a healthcare provider before starting any new medication, including semaglutide, to ensure it is safe and appropriate for you.
Where to Buy Semaglutide for Weight Loss
Since semaglutide is a prescription medication, it is not available for purchase over the counter. In order to obtain semaglutide for weight loss purposes, you will need to consult with a healthcare provider who can evaluate whether it is a suitable option for you. If semaglutide is deemed appropriate, your healthcare provider can write you a prescription that can be filled at a pharmacy.
In some cases, healthcare providers may be hesitant to prescribe semaglutide for weight loss, as it is not yet approved by the FDA specifically for this purpose. However, many providers are willing to prescribe medications off-label if they believe it will benefit their patients. It is important to have an open and honest discussion with your healthcare provider about your weight loss goals and to work together to develop a plan that is safe and effective for you.
If you are having trouble finding a healthcare provider who is willing to prescribe semaglutide for weight loss, you may want to consider seeking out a weight loss clinic or specialist who is familiar with the medication. These providers may be more knowledgeable about the use of semaglutide for weight loss and more willing to prescribe it off-label.
Benefits of Semaglutide for Weight Loss
There are several potential benefits of using semaglutide for weight loss. Studies have shown that semaglutide can lead to significant weight loss compared to a placebo, with some participants losing up to 15% of their body weight. In addition to weight loss, semaglutide has been shown to improve other health markers, such as blood sugar control, blood pressure, and cholesterol levels.
Another benefit of semaglutide is its convenience. The medication is taken as a once-weekly injection, which can be done at home. This can be more convenient for some individuals than having to take daily medications or remember to take pills several times a day.
In addition to its weight loss benefits, semaglutide has also been shown to reduce the risk of developing other weight-related health conditions, such as type 2 diabetes and cardiovascular disease. By helping individuals achieve and maintain a healthier weight, semaglutide can have long-term benefits for overall health and well-being.
Potential Side Effects of Semaglutide
Like any medication, semaglutide may cause side effects in some individuals. Common side effects of semaglutide include nausea, vomiting, diarrhea, and constipation. These side effects are usually mild and tend to improve over time as the body adjusts to the medication.
More serious side effects of semaglutide are rare but can include pancreatitis, kidney problems, and thyroid tumors. It is important to be aware of these potential risks and to consult with a healthcare provider if you experience any concerning symptoms while taking semaglutide.
If you are considering taking semaglutide for weight loss, it is important to weigh the potential benefits against the potential risks and to discuss any concerns with your healthcare provider. They can help you determine if semaglutide is a safe and appropriate option for you and can monitor you for any potential side effects while taking the medication.
Conclusion
Semaglutide is a medication that has shown promise in aiding weight loss, but it is important to approach it as part of a comprehensive weight loss program that includes healthy lifestyle changes. If you are interested in trying semaglutide for weight loss, consult with a healthcare provider who can evaluate whether it is a suitable option for you and provide guidance on how to use it safely and effectively.
Remember that weight loss is a journey that requires commitment and dedication, and there is no one-size-fits-all solution. Semaglutide may be a helpful tool in your weight loss arsenal, but it is not a substitute for healthy eating and regular exercise. By working with a healthcare provider and making sustainable lifestyle changes, you can achieve long-term success in your weight loss goals.
Take the time to research and educate yourself about semaglutide and its potential benefits and risks, and make an informed decision about whether it is the right choice for you. With the right support and guidance, you can embark on a journey towards a healthier weight and a healthier life.
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Obesity continues to be a growing concern worldwide, with countless individuals struggling to achieve and maintain a healthy weight. In recent years, there has been increased interest in the use of medications to aid in weight loss efforts. One such medication that has gained attention is semaglutide. Originally approved for the treatment of type 2 diabetes, semaglutide has shown promising results in promoting weight loss in individuals without diabetes. However, as with any medication, there are potential side effects to consider.
Overview of Semaglutide
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that works by mimicking the action of the hormone GLP-1 in the body. GLP-1 is involved in regulating blood sugar levels and appetite, making it a promising target for weight loss treatment. Semaglutide is administered as a once-weekly injection and is typically used in conjunction with diet and exercise to promote weight loss.
Studies have shown that semaglutide can lead to significant weight loss in individuals with and without diabetes. In one clinical trial involving individuals with obesity, participants who received semaglutide lost an average of 15-20% of their body weight over a 68-week period. These results have sparked interest in the use of semaglutide as a potential treatment for obesity.
Despite its promising benefits, semaglutide is not without potential side effects. Like other GLP-1 receptor agonists, common side effects of semaglutide include nausea, vomiting, diarrhea, and constipation. These gastrointestinal side effects are typically mild to moderate in severity and may improve over time as the body adjusts to the medication.
Potential Risks and Considerations
In addition to gastrointestinal side effects, there are other potential risks and considerations to be aware of when taking semaglutide for weight loss. One concern is the potential for pancreatitis, a rare but serious inflammation of the pancreas. While the risk of pancreatitis with semaglutide appears to be low, it is important to be vigilant for symptoms such as severe abdominal pain, nausea, and vomiting.
Another potential risk of semaglutide is the possibility of thyroid tumors. In preclinical studies, semaglutide has been shown to increase the risk of thyroid C-cell tumors in rodents. While the relevance of these findings to humans is not yet fully understood, it is important to consider this potential risk when using semaglutide for weight loss.

Other potential side effects of semaglutide may include low blood sugar (hypoglycemia), injection site reactions, and an increased heart rate. It is important to discuss any concerns or questions with a healthcare provider before starting treatment with semaglutide.
Conclusion
In conclusion, semaglutide shows promise as a potential treatment for weight loss in individuals with obesity. While the medication has been shown to be effective in promoting weight loss, it is not without potential side effects. It is important to weigh the benefits and risks of semaglutide carefully and to work closely with a healthcare provider to monitor for any adverse effects. By staying informed and proactive, individuals can make informed decisions about their weight loss journey with semaglutide.
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