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How Testosterone Affects Fat Loss: Real Science of Low-T | Thomas DeLauer: I'm sick of the lack of legitimacy behind testosterone, so let's clear some of this up. I work with a lot of men that are battling Low-T by helping them with their lifestyle at http://www.ThomasDeLauer.com As men age, their testosterone levels decline. This is exacerbated by an increase in SHBG (sex-hormone binding globulin), which binds to testosterone and thus reduces the amount of free testosterone in the body. Low testosterone levels have been linked to obesity and many other health problems, including fatigue, memory problems and reduced muscle and bone mass. So what is the impact of testosterone on body fat? Testosterone and energy - low levels of testosterone are linked with low energy levels. Regaining regular testosterone levels can increase energy and lead to weight loss. Studies have found that testosterone supplementation reduces total body fat percentages. Obesity is often correlated with low testosterone levels in men. Just as testosterone therapy is associated with decreased obesity, losing weight is associated with increased testosterone levels. An article published in 2014 in the journal of Current Opinion in Endocrinology, Diabetes and Obesity looked at the existing data regarding testosterone therapy in overweight and obese men with testosterone deficiency (hypogonadism). -Many weight loss supplements have dangerous side effects or are ineffective -Looked at weight loss, BMI, waist circumference and body composition -Evaluated long-term testosterone therapy -About 40% of obese nondiabetic men and 50% of obese diabetic men over 45 have low levels of free testosterone -Many studies have found that testosterone therapy in obese men is correlated with increased lean body mass, weight loss, decreased BMI and reduced waist circumference. -Weight loss is significant and sustained with long-term testosterone therapy Testosterone plays a part in protein, fat and carbohydrate metabolism. -Testosterone is involved with mitochondrial function and thus energy production and utilization -This interference with energy production is likely why those with low testosterone levels experience a lack of energy -Testosterone therapy has been found to increase lipid oxidation and normalize glucose use in the body. It was found to increase energy and motivation. Weight gain is associated with an 88% increase in body fat and a 12% increase in lean body mass (LBM) and weight loss with a 72% decrease in body fat and a 28% decrease in LBM. -With testosterone therapy LBM has been shown to increase. -Increased LBM means increased energy expenditure at rest -Testosterone therapy is also associated with improved cardiometabolic function Testosterone deficiency is linked with a decrease in energy metabolism from fat and an increase in energy metabolism from glucose. -Testosterone therapy has been shown to increase lipid metabolism Safety? Safety is the main concern with testosterone replacement therapy. Possible risks discussed in literature include: -Increased risk of prostate and breast cancer -Liver toxicity and tumors -Sleep apnea exacerbation -Testicular infertility and atrophy It is necessary to talk with your doctor before starting testosterone therapy. Summary: If you are a male struggling to lose weight, testosterone therapy is a promising treatment to help with not only weight loss but body composition, energy levels and overall health. References: 1. Dose-dependent effects of testosterone on regional adipose tissue distribution… http://press.endocrine.org/doi/10.1210/jc.2003-031492?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed 2. Testosterone and weight loss: the evidence https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154787/ 3. Effects of testosterone treatment on body fat and lean mass in obese men on a hypocaloric diet… https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054608/ 4. The benefits and risks of testosterone replacement therapy: a review https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2701485/

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What happens inside your body when you take steroids? Find out all the benefits and side effects of steroid use. If you're wondering if you do lose muscle when you stop taking steroids or testosterone injections this video will help. Whether you're trying to learn more about anabolic steroids or the effects that large doses of testosterone and sarms have on your body, this video will help. 🔥 FREE 6 Week Shred: https://GravityTransformation.com 📲 FREE Diet/Workout Planner Tool: http://bit.ly/2N41lTX Steroids can help you build a massive amount of muscle, increase your strength, and drastically speed up your recovery. But they can also come with some serious side effects, especially for many beginners that rush in without knowing what they're doing. So today i want to go over exactly what happens to the human body on steroids based on science. Now before we jump in I want to mention that I don't personally have any first-hand experience with steroids, but I have spent countless hours researching the topic, so I'll do my absolute best to give you a non-bias science-based summary of the effects that steroids have on your body. Now the first thing you have to know is that not all steroids are the same. The term “steroid” refers to a biologically active organic compound with four rings arranged in a specific molecular configuration. So even a corticosteroid is still considered a steroid since it has this same kind of four ring structure and corticosteroids are considered relatively safe. They're even routinely prescribed by doctors to help lower inflammation in the body, caused by things like swelling due to an injury, allergic reactions, and even asthma. Although many of you already know about corticosteroids, it may surprise you to learn that both cholesterol and estrogen are actually also considered steroids because they have the same four rings, but for the rest of the video when I say steroids I'm referring to the type of steroids that are predominantly used for enhancement purposes known as an anabolic-androgenic steroid. This is a type of steroid that mimics the effects of testosterone in your body. Normally your testes will produce four to nine milligrams of testosterone per day in an average healthy male. But by taking synthetic testosterone, you'll vastly increase the amount of testosterone that flows through your veins. Your body then treats that exogenous testosterone in the same way as if it were your body's own testosterone. So the testosterone enters your cells and binds to what's known as androgen receptors. From there, it binds to the nucleus of the cell and attaches to DNA. This process activates hundreds of genes involved in stimulating protein synthesis and reducing protein breakdown. So as a result, your muscles are more likely to stay in a "positive protein turnover rate,” which benefits muscle growth because to build muscle, more protein needs to be built up compared to the amount that gets broken down. And this is how steroids assist with muscle growth, and why they're so popular amongst bodybuilders. Now aside from improving protein turnover rate anabolic steroids also increase the number of nuclei that are found within muscle cells. Those nuclei, which are actually called myonuclei, happen to be the control center of each muscle. So having more nuclei is beneficial because the number of nuclei you have within a muscle is actually one of the primary factors that determine your potential for growth. To put it simply the more myonuclei, the bigger the muscle can become. (3) And this is actually one reason why some people have better muscle-building genetics because they naturally have more myonuclei, while others don't. (4) You see, the nuclei in your muscle fibers are limited to a maximum region of the cell that they can control. This is an area known as the myonuclear domain. Once the growth of a particular muscle fiber exceeds this domain, the only way to further grow is to add new nuclei to that cell. And that process is called 'myonuclear addition.' Now the problem is that normally, it takes a lot of time to add new nuclei to a muscle. That’s why you can’t gain 20 pounds in let's say one month. But by taking steroids, you can gain muscle much faster because it significantly increases the speed at which your body can add new nuclei to muscle tissue. And once it's there the new nuclei remain in your muscle tissue for the rest of your life. We can see this play out in studies in which steroids were given to mice. 3 months after stopping the use of steroids, the mice had their muscle mass return to normal, but the extra nuclei stayed there. (5) That’s why taking steroids not only increases muscle mass in the short term, but it can also increase the amount of muscle that you can build and maintain for the rest of your life. So even if someone that once took steroids stopped taking steroids, they would most likely lose some mass, but their muscles would still have a higher...

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