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0:00 Does the Evidence Support Any Natural "T-Boosters"? 1:23 Intro To Randomised Control Trials 2:25 Fenugreek Seed Extract Evidence 3:15 Ashwagandha Evidence 4:39 Tribulus Terrestris Evidence 5:08 Maca Evidence 5:37 Asian ("Panax") Ginseng Evidence 6:10 Fadogia agrestis 6:36 Forskolin The Scientific Evidence on Popular Natural Testosterone Boosting Supplements. In this video, Doctor Owen, Medical Doctor and Chemist, summarises the findings of all the currently available randomised control trials on natural testosterone-boosting supplements. Because this video looks only at randomised control trials on humans, some popular "testosterone booster" supplements are omitted because they remain totally unproven. The video explores the mostly positive data behind fenugreek seed extract and ashwagandha, including a suggestion for the future direction of ashwagandha testosterone research (pitting root extract versus leaf extract). It goes on to explore Tribulus, Maca and Asian Ginseng. Four randomised control trials failed to provide any evidence that Tribulus terrestris boosts testosterone levels in humans. And three randomised control trials failed to show any evidence that Maca powder increases testosterone levels in humans. As for Asian Ginseng, 6 of 7 RCTs failed to show a statistically significant difference versus placebo, with just 1 finding a significant positive effect. The last section of the video addresses the total or near-total dearth of high-quality human trial data on Fadogia agrestis and Forskolin, which to different extents, are both popular natural supplements taken for supposed testosterone-boosting effects. In summary, this video details the currently available scientific evidence and stresses the need for more data. Specifically, more data is needed on these supplements in females, longer-duration trials and long-term safety data. I hope this summary video is informative and of use to some. **Medical Disclaimer: I do not advocate taking any of these supplements on the relatively scarce data on effectiveness and safety currently available and instead advocate being a “late adopter” once more safety data becomes available.** ** All the information contained in this video is not intended nor implied to constitute professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained in this video is for general informational purposes only and does not replace a consultation with your own doctor/health professional ** Links to all referenced science: - Fenugreek seed extract & testosterone RCTs: https://ffhdj.com/index.php/ffhd/article/view/565 https://scholar.google.com/scholar_lookup?journal=Asian+J+Pharm+Clin+Res&title=Effects+of+glycosides+based+fenugreek+seed+extract+on+serum+testosterone+levels+of+healthy+sedentary+male+subjects:+an+exploratory+double+blind,+placebo+controlled,+crossover+study&volume=7&issue=Suppl+2&publication_year=2014&pages=177%E2%80%9081& https://pubmed.ncbi.nlm.nih.gov/31828857/ https://www.tandfonline.com/doi/full/10.3109/13685538.2015.1135323 https://pubmed.ncbi.nlm.nih.gov/30356905/ https://pubmed.ncbi.nlm.nih.gov/21116018/ - Ashwagandha ("Withania Somnifera") & testosterone RCTs: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863556/ https://journals.sagepub.com/doi/pdf/10.1177/1557988319835985 https://pubmed.ncbi.nlm.nih.gov/31517876/ https://www.tandfonline.com/doi/full/10.1186/s12970-015-0104-9 - Tribulus & testosterone RCTs: https://journals.sagepub.com/doi/abs/10.1177/0391560318802160?journalCode=urja https://www.sciencedirect.com/science/article/abs/pii/S0378512216302973 https://www.sciencedirect.com/science/article/abs/pii/S0378874105003314 https://www.sciencedirect.com/science/article/abs/pii/S2173578614000523 - Maca & testosterone RCTs: http://eplant.njau.edu.cn/maca/publication/Effect%20of%20Lepidium%20meyenii%20(Maca),%20a%20root%20with%20aphrodisiac%20and%20fertility-enhancing%20properties,%20on%20serum%20reproductive%20hormone%20levels%20in%20adult%20healthy%20men.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569766/ https://pubmed.ncbi.nlm.nih.gov/19260845/ - Asian Ginseng & testosterone RCTs: https://pubmed.ncbi.nlm.nih.gov/11991768/ , https://pubmed.ncbi.nlm.nih.gov/23254461/ , https://pubmed.ncbi.nlm.nih.gov/16855773/ , https://pubmed.ncbi.nlm.nih.gov/26860800/ , https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735289/, https://pubmed.ncbi.nlm.nih.gov/11798012/ , https://pubmed.ncbi.nlm.nih.gov/25967606/ - Fadogia Rat Erectile-Dysfunction Study: https://pubmed.ncbi.nlm.nih.gov/16281088/ - Forskolin & Testosterone RCT: https://jissn.biomedcentral.com/articles/10.1186/1550-2783-2-2-54

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Disclaimer: This video is not intended to provide diagnosis, treatment or medical advice. Information obtained from this video should not be taken in lieu of your own medical provider's advice and treatment plan. Please consult directly with a physician or other healthcare professional regarding any diagnosis or treatment plan options. Content provided on this Youtube channel is for informational purposes only and should not be considered as a substitute for advice from a healthcare professional. The statements made about specific products throughout this video are not to diagnose , treat, cure or prevent disease. As always, consult with your medical doctor if you have any questions specific to your medical situation.

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