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Register for this webinar: https://xtalks.com/webinars/sarcopenia-changes-and-challenges-in-body-composition-with-glp-1-receptor-agonist-based-weight-loss-therapies/?utm_source=youtube&utm_medium=videopromo&utm_campaign=24q242 Recent trials of GLP-1 receptor agonist-based therapies using weight loss primary endpoints have shown remarkable efficacy that approaches that of bariatric surgery (~20–25 percent compared to 25–30 percent with bariatric surgery). GLP-1 receptor agonist-based therapies have also shown compelling benefits on other obesity comorbidities such as glycaemic control in type 2 diabetes, cardiovascular disease risk, progression of chronic kidney disease, obstructive sleep apnea and metabolic-dysfunction associated steatotic liver disease. Although changes in fat distribution from GLP-1 receptor agonist-based therapies are key to understanding many of the health outcome benefits, the impact of skeletal muscle loss on long-term health outcomes remains to be clarified. While skeletal muscle loss is not specific to GLP-1 receptor agonist-based therapies, the degree of weight loss compared to other anti-obesity medications (AOMs) has exposed the limitations of using weight change as a primary endpoint in clinical trials and has highlighted the need for including accurate measurements of changes in muscle mass and function in AOM clinical trials. The evolving requirement for accurate assessment of body composition (BC) in clinical trials is further driven by: - The variability of changes in fat loss and BC changes to different GLP-1 receptor agonist-based therapies - The variable changes in BC of diverse ethnic and racial populations in response to GLP-1 receptor agonist-based therapies - The expansion of treatment populations by GLP-1 receptor agonist-based therapies to include adolescents with obesity - The development of new therapies aimed at preserving muscle mass and function - Understanding changes in regional adiposity such as pathogenic visceral adipose tissue, liver adipose tissue and epicardial adipose tissue In this webinar, the speakers will review recent clinical trial data that represents the current state of scientific knowledge and evaluate the impact of the data on loss of muscle mass following GLP-1 receptor agonist-based therapies and the need for accurate and tailored assessments of BC in clinical trials. Register for this webinar today to delve into the latest clinical trial data on GLP-1 receptor agonist-based therapies and their impact on weight loss and body composition. Register for this webinar: https://xtalks.com/webinars/sarcopenia-changes-and-challenges-in-body-composition-with-glp-1-receptor-agonist-based-weight-loss-therapies/?utm_source=youtube&utm_medium=videopromo&utm_campaign=24q242 #Obesity #DrugDevelopment #ClinicalResearch #ClinicalData #TherapeuticAreas #WeightLoss #BodyComposition #FattyLiver #Sarcopenia #GLP1Agonist #GLP1Agonists #GLP1Drugs

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Employees of Hospitals, Schools, Universities and Libraries may download FREE medical animations from Nucleus by signing up for a free trial: http://nmal.nucleusmedicalmedia.com/free-trial-membership-a #BariatricSurgery #weightlosssurgery #weightloss MEDICAL ANIMATION TRANSCRIPT: If you suffer from severe obesity and have been unable to lose weight, your doctor may recommend robotic bariatric surgery. Your digestive system or gastrointestinal tract includes your mouth, esophagus, stomach, small intestine, and large intestine. Your pancreas, liver, and gallbladder squirt digestive juices into your small intestine to help you break down the food you eat. Your doctor may recommend bariatric surgery if you are unable to lose weight and keep it off through diet and exercise alone, have a body mass index or BMI above 40, have a BMI above 35 and you have a life threatening condition such as heart disease or diabetes, or weigh more than 100 pounds over your ideal body weight or IBW. Bariatric surgery helps you lose weight by decreasing the size of your stomach so that it holds less food and makes you feel full more quickly. Before your procedure, an intravenous line or IV will be started. You may be given antibiotics through the IV to decrease your chance of infection. You'll be given general anesthesia. A breathing tube will be inserted through your mouth and down your throat to help you breathe during the operation. Your surgeon will make a small incision near your belly button and insert a plastic tube called a port. Carbon dioxide gas will be pumped into your abdomen through this port. The gas will inflate your abdomen, giving your surgeon more room to see and move the surgical tools. After your abdomen is inflated, a high definition camera will be inserted into this port. Your surgeon will make additional port incisions for robotic instruments, as well as for instruments used by patient side assistance. An assistant will insert all of the robotic tools through these ports. Unlike standard laparoscopic instruments, these tools can rotate 360 degrees and have more flexibility than the human wrist. Seated at a special console, your surgeon will operate the robotic arms and the camera with joystick-like controls and foot pedals. A computer will translate the exact movements of your surgeon's fingers into precise movements of the surgical tools. At the same time, a high definition vision system will provide a magnified, three dimensional stereoscopic view of the surgical area. One common robotic bariatric surgical procedure is a gastric sleeve procedure. In this procedure, most of your stomach will be removed, leaving a smaller sleeve-like tube about the size of a banana. To create the gastric sleeve, your surgeon will cut and staple your stomach at the same time. The part of your stomach separated from the gastric sleeve will be removed through one of the incisions. The remaining gastric sleeve does not change where food enters and leaves your stomach. At the end of your procedure, the incisions will be closed with stitches, staples, surgical glue, or closure tape dressings. The incisions will be covered with sterile dressings. After your procedure, your breathing tube will be removed, and you will be taken to the recovery area for monitoring. You'll be given pain medication as needed. You may continue to receive antibiotics through your IV. Most patients are released from the hospital one to two days after the procedure. ANR17010

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Are you struggling to lose weight and looking for a convenient and tasty solution? Weight loss gummies have gained popularity in recent years as a convenient and enjoyable way to supplement your weight loss efforts. One popular retailer of weight loss gummies is Dischem, a well-known pharmacy chain in South Africa. But are Weight Loss Gummies Dischem truly effective for shedding pounds? In this article, we will explore the effectiveness of weight loss gummies and whether they can help you achieve your weight loss goals.

Do Weight Loss Gummies Dischem Work?

Weight loss gummies from Dischem claim to help support weight loss by curbing cravings, boosting metabolism, and increasing energy levels. These gummies are typically made with natural ingredients such as green tea extract, garcinia cambogia, and apple cider vinegar, which are known for their weight loss properties. However, it’s essential to remember that weight loss gummies are not magic pills and should be used in conjunction with a healthy diet and regular exercise for best results.

One of the key ingredients found in many weight loss gummies is green tea extract. Green tea has been shown to boost metabolism and promote fat loss, making it a popular choice for weight loss supplements. Garcinia cambogia is another common ingredient in weight loss gummies that is believed to help suppress appetite and block the production of fat. Apple cider vinegar is also commonly included in weight loss gummies for its ability to support digestion and promote feelings of fullness.

How to Use Weight Loss Gummies Dischem

When using weight loss gummies from Dischem, it’s essential to follow the recommended dosage instructions provided on the packaging. Typically, you will be advised to take a certain number of gummies per day, usually before meals. It’s crucial not to exceed the recommended dosage, as this can lead to adverse effects and may not be more effective in helping you lose weight.

In addition to taking weight loss gummies, it’s essential to maintain a healthy and balanced diet rich in fruits, vegetables, lean proteins, and whole grains. Incorporating regular exercise into your routine, such as cardio and strength training, can also help support your weight loss goals. Drinking plenty of water and getting an adequate amount of sleep are also vital for overall health and weight loss.

Potential Side Effects of Weight Loss Gummies

While weight loss gummies from Dischem are generally considered safe when taken as directed, they may cause some side effects in certain individuals. Common side effects of weight loss gummies may include digestive issues such as bloating, gas, and diarrhea, especially if the gummies contain a high amount of fiber or stimulants. It’s essential to monitor how your body reacts to the gummies and discontinue use if you experience any adverse effects.

It’s also important to note that weight loss gummies are not regulated by the FDA, so the quality and efficacy of these products may vary. It’s essential to do your research and choose reputable brands, such as Dischem, that have a good reputation for quality and safety. Consulting with a healthcare professional before starting any new weight loss supplement is also recommended, especially if you have any underlying health conditions or are taking medication.

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The Shark Tank Keto craze has taken the diet world by storm, with many people swearing by its effectiveness in helping them shed pounds and improve their overall health. But where did this all begin? How did the Original Shark Tank Keto come to be? Let’s take a closer look at the origins of this popular diet trend and how it has evolved over the years.

The Birth of the Shark Tank Keto Diet

The Shark Tank Keto diet first gained mainstream attention when it was featured on the hit reality TV show Shark Tank. Entrepreneurs presented their keto products to the panel of celebrity investors, who were intrigued by the potential of the keto diet to help people lose weight and improve their health. The sharks were impressed by the science behind the keto diet, which involves cutting out carbohydrates and replacing them with high-fat, moderate-protein foods to put the body into a state of ketosis.

One of the most memorable moments on the show was when entrepreneur Anna and Samantha Martin presented their keto weight loss pills, which they claimed could help people burn fat and lose weight quickly. The sharks were skeptical at first, but after hearing about the success stories of people who had tried the product, they quickly changed their tune. The Martin sisters walked away with a deal from one of the sharks, and the rest is history.

Since its appearance on Shark Tank, the Original Shark Tank Keto diet has become a household name, with millions of people around the world trying out the diet for themselves. The diet has been praised for its ability to help people lose weight, improve their energy levels, and even reduce the risk of chronic diseases like diabetes and heart disease.

The Evolution of Shark Tank Keto Products

Over the years, countless Shark Tank Keto products have hit the market, each claiming to offer a unique solution for those looking to embrace the keto lifestyle. From keto weight loss pills to keto meal replacement shakes, there is no shortage of options for those looking to try out the diet for themselves. However, not all Shark Tank Keto products are created equal, and it’s essential to do your research before diving into the world of keto supplements.

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One of the most popular Shark Tank Keto products is keto weight loss pills, which are designed to help people burn fat and lose weight quickly. These pills typically contain a blend of natural ingredients like BHB ketones, which are believed to help the body enter ketosis more quickly and efficiently. While some people swear by the effectiveness of these pills, others remain skeptical of their claims and prefer to stick to a more traditional approach to the keto diet.

Another popular Shark Tank Keto product is keto meal replacement shakes, which are designed to make it easier for people to stick to the keto diet while on the go. These shakes typically contain a blend of high-fat, moderate-protein ingredients to help keep the body in ketosis and promote weight loss. Many people find these shakes to be a convenient and delicious way to stay on track with their keto goals, while others prefer to stick to whole foods to get their nutrients.

The Future of Shark Tank Keto

As the Original Shark Tank Keto diet continues to gain popularity, it’s clear that the keto craze is here to stay. With more and more people looking for effective ways to lose weight and improve their health, the keto diet offers a compelling solution that has stood the test of time. Whether you’re a seasoned keto enthusiast or you’re just starting your journey, there are plenty of Shark Tank Keto products out there to help you reach your goals.

So, what does the future hold for the Original Shark Tank Keto diet? Only time will tell, but one thing is for sure – the keto trend shows no signs of slowing down anytime soon. As more research is conducted on the benefits of the keto diet and new products hit the market, we can expect to see even more innovative ways to embrace the keto lifestyle and achieve our health and weight loss goals.

Whether you’re a die-hard Shark Tank fan or you’re just curious about trying out the keto diet for yourself, there’s never been a better time to jump on the keto bandwagon. With so many Shark Tank Keto products to choose from, the possibilities are endless – so why not give it a try and see what all the hype is about?

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