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CINCINNATI (Liz Bonis) -- When it comes to the power of pot a number of states now say it can legally be used to treat health concerns.You might be surprised to hear that it's hotly debated if weight loss is one of them.Unless you talk to Art Glass, the author of the book, The Marijuana Diet. Local 12 talked to him by Skype from a state where he admits he can't legally use pot yet for this purpose in spite of that he claims that after several years on the diet he's dropped 65 pounds.Here's how he says the marijuana diet works: you smoke one to three inhales of marijuana, eat superfoods such as blueberries or green leafy vegetables, juice with green smoothies and fast intermittently.Then you do what Art calls, sofa exercises, which he showed Local 12 by Skype.Glass says the weed is what works for weight loss and he has studies and testimonials to back it up.Because marijuana has cannibinoids in it, it is the only plant that has that, and cannibinoids do incredible things for peoples minds and their bodies.So the real question then Liz Bonis had to ask is, is it really the marijuana? Or perhaps the reduced calorie intake that might be leading to weigh loss. And as you might imagine, experts have a bit of a mixed opinion about using controlled substances to help you lose weight. Doctor George Kerlakian is a bariatric surgeon who reviewed the marijuana diet and some of the studies Glass claims support weed for weight loss:When you look at studies like the ones that have been reported, you really have to look very carefully at the statistics, and whether or not in what we call in statistics are confounding factors. In the sampling of patients in their study, they could have included a lot of patients who initially were depressed or ill with chronic illnesses who then tried to use marijuana or other types of substances, but nonetheless, started out much smaller , with smaller waistlines, and lower cholesterol etc.Doctor Kerlakian says he would not recommend the marijuana diet for any of his patients. And when Local 12 asked if pot helps you drop pounds?I don't believe so, I think that is a myth, and if anything as you are well aware, often marijuana is recommended as a prescribed substance for patients who have chronic illnesses, cancer, HIV aids to improve their appetite.He says it's likely to increase, rather than decrease, eating.Because obviously it gives the patient some euphoria some feeling better and in touch with themselves and maybe improves their appetite this way.Art Glass doesn't disagree that marijuana can give you the munchies. But studies have shown that people who smoke marijuana eat more and weigh less.Doctor Kerlackian says in spite of that claim, if you weed out the facts, would he suggest marijuana diet for anyone who wants to lose weight?I would not. Absolutely not.

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In this episode of the Pharm So Hard Podcast, the hosts discuss GLP-1 receptor agonists, a class of medications used to manage blood sugar levels in patients with type 2 diabetes and to treat obesity. They provide an overview of the history and development of GLP-1 receptor agonists, highlighting their clinical superiority and various benefits. The hosts also explain the role of GLP-1s in the body, including their glucose-dependent insulin secretion and effects on gastric emptying. They discuss the impact of GLP-1s on hunger and mental health, emphasizing the reduction of food noise and improvement in satiety levels. Additionally, they differentiate GLP-1 receptor agonists for diabetes and weight loss and explore their indications and guideline positioning. Takeaways • GLP-1 receptor agonists are a class of medications used to manage blood sugar levels in patients with type 2 diabetes and to treat obesity. • GLP-1 receptor agonists have shown clinical superiority to other anti-hyperglycemic drugs, improving glycemic control, reducing weight loss and blood pressure, and providing cardio-protective benefits. • GLP-1s increase glucose-dependent insulin secretion, block glucagon secretion, and slow gastric emptying, leading to improved blood sugar control and increased satiety. • GLP-1 receptor agonists have a positive impact on mental health, reducing food noise and helping individuals make healthier food choices. • Different GLP-1 receptor agonists have specific indications for diabetes and weight loss, and their use is guided by clinical guidelines. • GLP-1 receptor agonists are FDA-approved for improving glycemic control in patients with type 2 diabetes and for the treatment of obesity. • The choice of GLP-1 receptor agonist depends on factors such as comorbidities, weight loss goals, and patient preferences. • GLP-1 receptor agonists have different dosing regimens, and the specific dose may vary based on the indication and the product. • Common side effects of GLP-1 receptor agonists include nausea, vomiting, and diarrhea, but these side effects often improve with continued use and proper management. GLP-1 agonists can cause loss of appetite as a side effect. • GLP-1s are being used off-label for conditions such as NAFLD and depression. • GLP-1s may have positive effects on bone health and blood pressure. • The high cost of GLP-1s poses challenges for patient access. Chapters 00:00 Introduction to GLP-1 Receptor Agonists 01:12 History and Development of GLP-1 Receptor Agonists 06:14 The Role of GLP-1s in the Body 09:38 Effects of GLP-1s on Hunger and Mental Health 11:17 Differentiation of GLP-1 Receptor Agonists for Diabetes and Weight Loss 11:44 Indications and Guideline Positioning of GLP-1 Receptor Agonists

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