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CardioNerds (Drs. Gurleen Kaur and Richard Ferraro) and episode FIT Lead Dr. Spencer Carter (Cardiology Fellow at UT Southwestern) discuss the clinical implementation of GLP-1 receptor agonists with Dr. Neha Pagidapati (Faculty at Duke University School of Medicine). In this episode of the CardioNerds Cardiovascular Prevention Series, we discuss the clinical implementation of glucagon-like peptide-1 (GLP-1) receptor agonists. We cover the clinical indications, metabolic and cardiovascular benefits, and potential limitations of these emerging and exciting therapies. Show notes were drafted by Dr. Spencer Carter. Audio editing was performed by CardioNerds Academy Intern, student Dr. Pacey Wetstein. This episode was produced in collaboration with the American Society of Preventive Cardiology (ASPC) with independent medical education grant support from Novo Nordisk. See below for continuing medical education credit. Claim CME for this episode HERE. CardioNerds Prevention PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls and Quotes - Clinical Implementation of GLP-1 Receptor Agonists GLP-1 agonists work through a variety of mechanisms to counteract metabolic disease. They increase insulin secretion, inhibit glucagon secretion, slow gastric motility, and increase satiety to limit excess energy intake. Patients with type II diabetes and an elevated risk for atherosclerotic cardiovascular disease should be considered for GLP-1 agonist therapy regardless of hemoglobin A1c. GLP-1 agonists offer significant ASCVD risk reduction even in the absence of diabetes. Newer data suggest a significant reduction in cardiovascular events with GLP-1 agonist therapy in patients who are overweight or obese and have a prior history of heart disease. GLP-1 agonists should generally be avoided in patients with a history of medullary thyroid cancer or MEN2. As these medications slow gastric emptying, relative contraindications include history of recurrent pancreatitis and gastroparesis. GLP-1 agonists should be initially prescribed at the lowest dose and slowly uptitrated to avoid gastrointestinal side effects. Show notes - Clinical Implementation of GLP-1 Receptor Agonists What were the groundbreaking findings of the STEP1 and SURMOUNT-1 trials and how these impact cardiovascular wellness? The STEP1 and SURMOUNT trials demonstrated sustained clinically relevant reduction in body weight with semaglutide and tripeptide, respectively, in patients with overweight and obesity. As obesity is an important risk factor for the development of cardiovascular disease, weight reduction meaningfully contributes to cardiovascular wellness. What were the findings of the LEADER trial and their implications for patients with type II diabetes and high cardiovascular risk? The LEADER trial demonstrated a significant reduction in the rate of cardiovascular death, nonfatal MI, or nonfatal stroke in patients with type II diabetes treated with liraglutide. GLP-1 receptor agonist therapy should be considered in all patients with type II diabetes and elevated ASCVD risk regardless of A1c or current hyperglycemic therapy. What are current indications for GLP1 agonists in the context of cardiometabolic disease. GLP-1 receptor agonists should be considered in patients with type II diabetes and high ASCVD risk OR patients without diabetes who are overweight/obese and have a history of cardiovascular disease. What are important side effects or contraindications to GLP1 agents when used for cardiovascular risk reduction and wellness? GLP-1 receptor agonists should be avoided in patients with a history of medullary thyroid cancer or MEN2. Relative contraindications include recurrent pancreatitis, gastroparesis,

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Best Food to Lose Belly Fat NATURALLY at Home | Effective Weight Loss Tips Are you struggling with stubborn belly fat? Look no further! In this video, we share the 5 best foods to lose belly fat and transform your diet for effective weight loss. Incorporate these nutrient-dense foods into your meals to boost metabolism, curb hunger, and achieve your weight loss goals. Why You Should Watch: Gain insights into the latest nutrition research for losing belly fat. Get practical tips for easily incorporating these foods into your daily diet. Learn how to create balanced meals that promote a healthy lifestyle. 👉 Join the Health Blankett community for more weight loss tips, healthy recipes, and wellness advice! Don’t forget to like, comment, and subscribe for the best health content! 🔔 Hit the bell icon so you never miss an update! #BestFoodsToLoseBellyFat #LoseBellyFatNaturally #WeightLossTips #FoodsForFlatStomach #NaturalWeightLoss #BellyFatBurningFoods #HealthyEatingForWeightLoss #HomeWeightLossRemedies #FatBurningFoodsAtHome #EasyWeightLossDiet 5 best foods to lose belly fat naturally at home | health blankett

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For More Information and to Buy this Product Click the Given Link Active Luxe Keto Blend claims to get you into ketosis. And, that’s a natural fat burning process your body does. Usually, your body runs on carbs. So, it makes energy from the food you eat. Well, during ketosis, your body makes energy from its own fat stores. And, for anyone trying to lose weight, that’s ideal, because you’re burning fat. Well, Active Luxe Keto Pills claim to help you stay in ketosis longer and burn even more fat than you can alone. And, that’s why we wanted to investigate this pill. Beyond that, they also claim they have the right ingredients to lower your cortisol levels and make you feel more relaxed. This is a lot of claims for one little pill. So, let’s find out if the Active Luxe Keto Ingredients live up to their claims. And, if this product can truly help you lose any weight. Facebook: https://www.facebook.com/HealthSuperClub/ Twitter: https://twitter.com/HealthSuperClu1

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ACV Keto Gummies are a new product that has caught attention in the health and wellness sector; they claim to help lose weight and improve body health. Their appearance on Shark Tank, the popular TV show, has made them even more popular. This article will analyze ACV Keto Gummies’ impact on Shark Tank and assess if it is worth all the hype.

Shark Tank Appearance

The very first presentation on Shark Tank caught the eyes of all sharks in view of one thing – ACV Keto Gummies. The entrepreneurs who made this product boldly maintained that their gummies were a natural and efficient way of shedding some fat as well as boosting energy levels. With good science behind it and happy customers, sharks could not help but get impressed by this product. A deal was struck subsequently which led to its endorsement by some of industry’s most successful business minds.

ACV Keto Gummies gained popularity after their appearance on Shark Tank. They became a hot topic on social media where influencers and celebrities couldn’t stop talking about how effective they were. As a result, sales shot up making them absolutely necessary for anyone trying to achieve weight loss or who is on a keto diet.

Among various other weight loss supplements, ACV Keto Gummies differ materially because they incorporate both apple cider vinegar and ketogenic ingredients together. Apple cider vinegar aids digestion, minimizes inflammation while supporting weight reduction due to its numerous benefits for human health. Such action takes place when these are combined with ketogenic ingredients found in these gummies which then makes an unstoppable formula that can accelerate lipolysis while increasing energy levels at once.

Ingredients and Benefits

ACV Keto Gummies contain natural ingredients which have been scientifically proven to support weight loss efforts as well as general wellbeing of individuals using them. The major constituent of these gummies is apple cider vinegar that contains acetic acid known to promote fat burning process as well as maintain proper blood glucose level (Jenkins et al., 2017). Besides, the gummies have ketogenic ingredients including MCT oil and BHB salts which push an individual into ketosis, a state that burns fat stored in the body instead of carbs.

ACV Keto Gummies are especially advantageous because they are designed for use at one’s convenience. Instead of having to drink apple cider vinegar or take many supplements, ACV Keto Gummies can be chewed anytime if you get hungry. Therefore, it becomes easier to manage your weight even when constantly moving around or during travels.

Apart from this, ACV Keto Gummies are made out of real substances only without any artificial ingredients as well as preservatives or fillers. The significance of this is that you know what exactly you put in your system; hence it improves quality control at the highest level. These gummies are also gluten-free and vegan besides being non-GMO; thus suitable for those individuals who have strict dietary preferences.

Customer Reviews and Results

Customers who have tried ACV Keto Gummies since their appearance on Shark Tank never had enough good things to say about them. Numerous users have reported substantial drop in weight levels, better digestion and rising stamina after using these gummy candies regularly over time (Park et al., 2016). There were cases where people claimed such products was pivotal in smashing through some plateaus and exceeding set goals within a shorter period than anticipated.

In addition, ACV Keto Gummies are also favored by customers for their taste, with the users finding them very palatable and easy to include in their everyday routine. On the other hand, unlike traditional apple cider vinegar shots that might be harsh on one’s stomach and not pleasant to drink, a person can effortlessly take gummies instead.

Indeed, Shark Tank has had significant effects on ACV Keto Gummies. The show’s exposure has put the gummies at the center stage making them a go-to option for anyone looking to support their weight loss journey naturally and effectively. With customers giving positive reviews and sharks endorsing it, ACV Keto Gummies will keep revolutionizing health care sector.

With more people turning towards natural supplements in order to improve their health and wellbeing goals, ACV Keto Gummies have emerged as a standout product. These gummies have become popular mainly due to combining apple cider vinegar with ketogenic ingredients that aid weight loss process alongside energy enhancement as well as making someone healthy generally. If you are following keto diet or simply need an easier way of increasing your weight reduction efforts then this could be what you were seeking for; ACV Keto Gummies could be your answer.

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