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In this video, Laraine and Christopher Durham, collectively known as 'The Downsized', share their profound journey with GLP-1 weight loss medications, compounded Tirzepatide Zepbound and Mounjaro. Having lost significant weight throughout 54-55 weeks — 50 pounds for Laraine and 81 pounds for Christopher — they detail their experiences, including initial skepticism, the logistical challenges of obtaining medications, side effects, dietary changes, and health improvements such as reduced blood pressure and better sleep. They stress the importance of consulting a healthcare provider and the intricacies of managing prescriptions and insurance. The couple also offers insights into maintaining weight loss and the psychological impact of these medications. They emphasize that while the journey involved unexpected difficulties, the benefits far outweighed any challenges, making the entire process extremely rewarding. DOWNSIZED WEBSITE: https://thedownsized.org/ JOIN CLUB DOWNSIZED: https://www.youtube.com/@thedownsized/join DOWNSIZED GLP-1 COMPANION PRODUCT STORE: https://thedownsized.org/downsized-store We use Mochi Health: https://joinmochi.com/. Use Laraine’s code for $40 off: QIYGO8. 00:00 Introduction and Personal Stories 00:57 Starting the GLP-1 Journey 02:01 Initial Skepticism and First Experiences 03:41 Discovering Mounjaro, Zepbound and Compounded Medications 13:24 First Weeks on Medication 20:03 Navigating the Healthcare System 26:16 Unexpected Benefits and Side Effects 35:01 Managing Constipation and Side Effects 40:54 Navigating Dietary Changes 47:21 The Impact of GLP-1 Medications 52:21 Personal Experiences and Reflections 57:51 Advice for Newcomers and Final Thoughts

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Should prescription weight loss drugs like Ozempic and Wegovy be available to everyone, or should access be limited to those with obesity or diabetes? Hear the highlights from experts Dr. David Allison and Dr. Stuart W. Flint as they debate the ethics, risks, and benefits of making these powerful medications widely accessible. What do YOU think? Let us know in the comments. #ozempic #weightloss

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Bu bölümde Ayık Kafa podcast’in konuğu Dr. Sandra Kaufmann, MD. Bu, Dr. Kaufmann ile “yaşlanmama” planını konuştuğumuz sohbetin 2. bölümü, yani iki bölüm halinde yayınladığımız podcast’in devamı. Dr. Kaufmann, Johns Hopkins’te pediatrik anestezi alanında ihtisas yapmış, Joe DiMaggio Çocuk Hastanesi'nde Pediatrik Anestezi Şefi olarak görev yapmış ve The Kaufmann Anti-Aging Institute'i kurarak yaşlanma bilimi üzerine kapsamlı bir teori geliştiren ödüllü bir tıp doktorudur. Geçen hafta Yedi İlke’nin ilk 3’ünü ele almıştık; bugün seti tamamlıyoruz: 4. İlke Kalite Kontrolü: Hücreler bozuk DNA ve proteinleri nasıl onarır, otofajiyle çöpleri nasıl temizler? 5. İlke Bağışıklık Dengesi: Huysuz bir bağışıklık sistemi neden kronik iltihap, enfeksiyon ve kanser riskini artırır? 6. İlke Hücresel Özellikler: Beyin, kemik, deri gibi her hücre tipinin kendine özgü ömrü ve beslenme ihtiyacı vardır. 7. İlke Atık Yönetimi: Şeker kaynaklı “junk” Gelişmiş Glikasyon Son Ürünleri (AGE’ler) nasıl durdurulur? Hücreler tıkanmadan nasıl temizlenir? Kaufmann ayrıca yaygın sağlık alışkanlarının longevity üzerindeki etkilerini ve bu etkilerin nasıl azaltılabileceğini ele alıyor; mitokondrilerin enerji üretimi ve genel sağlık üzerindeki rolünü de anlatıyor. Takviye yönetiminin detaylarını da açıklayan Kaufmann, etkinlik düzeyi ve dozajın önemine de değiniyor. Sirtuinlerin hücresel sağlık ve longevity’deki kritik rolü, uyku ve sirkadiyen ritimlerin önemi ile AMP kinaz ve mTOR’un enerji düzenlemesindeki etkileşimi de konuşulan diğer başlıklar arasında yer alıyor. Ayrıca glikasyonun sağlık üzerindeki olumsuz etkileri ve vücutta etkili atık yönetiminin önemi ele alınıyor. Kaufmann, sağlığın korunmasında takviye ve ilaçların rolünü, yaşlanma mekanizmalarının anlaşılmasının gerekliliğini ve yaşam tarzı ile hedefe yönelik müdahalelerle hasarın nasıl azaltılabileceğini vurguluyor. Diyet içeceklerin etkisi, modern yaşamın toksinleriyle başa çıkma yolları, GLP-1 agonistleri kullanımı ve Kaufmann derecelendirme sistemiyle geliştirdiği özgün takviye öneri yaklaşımı da gündeme geliyor. Kaufmann, kişisel ilaç ve takviye deneyimlerini de paylaşarak sağlığa çok yönlü yaklaşımın önemini ortaya koyuyor. #EsraÇavuşoğlu #AyıkKafa #ElevatingLifeEvolvingHealth #Longevilab #DrSandraKaufmann #Longevity Dr. Sandra Kaufmann, MD: Web sitesi: https://kaufmannprotocol.com/bio Instagram: https://www.instagram.com/kaufmannlongevity/ *İş birlikleri ve Sponsorlar: https://dotshub.com/ T.C. İstanbul Gedik Üniversitesi’ne ne teşekkür ederiz. https://www.gedik.edu.tr/ *Kanalımıza üye olmak için 👉* https://www.youtube.com/@ayikkafa *Dr. Esra Çavuşoğlu, PhD* Instagram: https://www.instagram.com/esracavusoglu/ https://www.instagram.com/longevilab Web: https://www.longevilab.com/hakkimizda#esra-cavusoglu *Bize Ulaşmak İçin 👉* [email protected] *Ayık Kafa Hakkında* Dr. Esra Çavuşoğlu, PhD, kişisel tedavi deneyimlerinden başlayarak klinik psikoloji eğitimi ile devam eden çalışmalarını, yaptığı Bağımlılık odaklı doktorasını tamamlayarak bir üst aşamaya taşıdı. Ayık Kafa podcast'inde, Bağımlılık Hastalığı hakkında ilk elden bilgiler ve deneyimlerin yanı sıra son akademik çalışmalarını paylaşırken, Biohacking ve Longevity alanlarında dünyanın en yeni teknolojilerini, protokollerini, ürünlerini ve araştırmalarını ele alıyor. *Dr. Esra Çavuşoğlu, PhD Hakkında* Longevilab’in kurucusu Dr. Esra Çavuşoğlu, PhD, Amerika Birleşik Devletleri ve uluslararası düzeyde eğitimli bir klinik psikolog ve New York’ta sertifikalı bir bağımlılık terapistidir. Yale Üniversitesi Tıp Fakültesi Klinik Danışmanlık Kurulu’nda Uluslararası Gelişim Danışmanı olarak görev yapmıştır. Gaziantep Oya Bahadır Yüksel Rehabilitasyon Merkezi’nin kurucusu ve süpervizörüdür, Çavuşoğlu, Türkiye Rehabilitasyon Modeli’nin tasarımcısı ve uygulayıcısıdır. Dr. Esra Çavuşoğlu Türkiye’nin büyüyen bağımlılık sorunuyla mücadele etmek amacıyla Çağdaş Bağımlılık Çalışmaları Derneği’ni (ÇABAÇAD) kurmuştur.

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Have you ever wondered if the ketogenic diet is truly sustainable for long-term weight loss? It’s praised for quick results, but what happens after the initial success? In this video, we delve into the keto diet's impact on both physical and mental health, exploring whether it is safe and healthy for extended use. We'll discuss the ketogenic diet's benefits for weight loss and mental health while also addressing concerns about its long-term safety. Join us as we explain the keto diet and compare it with other low-carb diets. Is the keto diet healthy, or could it be bad for you? We aim to answer these questions by examining the potential risks and benefits of following a ketogenic lifestyle over time. We'll also cover important topics like transitioning off the keto diet and how this transition can affect your body and mind. Understanding the keto diet's impact on psychology is crucial, as it influences not just weight loss but also mental well-being. Is the keto diet safe long term, or are there hidden risks? We will provide insights into how to safely manage a ketogenic diet for sustainable weight loss and mental health benefits. If you're considering starting or continuing a ketogenic diet, or if you're curious about transitioning off keto, this video is for you. We hope to provide you with a comprehensive view of what it means to adopt a keto lifestyle and its implications on your overall health. Make sure to subscribe to MyBMB for more insightful content on health and wellness. Your journey to understanding whether the ketogenic diet is right for you starts here! ------------- You can also read my blog here: https://www.my-bmb.com/post/is-keto-sustainable-for-long-term-weight-loss ------------- Before you go, be sure to check out my video on whether protein powders are a waste of money. https://youtu.be/tQNRWMEQy-c Or you can also read my blog here: https://www.my-bmb.com/post/stop-wasting-money-on-protein-powders ------------- 00:00 Introduction 02:09 Challenges to long-term adherence and the psychological aspect of keto 04:08 The impact of UPFs in keto diets 06:19 Health impacts beyond weight loss 07:53 The role of individual differences in success 09:53 Transitioning off keto 11:22 Summary ------------ The My BMB Program Learn how to love your body and form a healthy relationship with food by empowering yourself with knowledge about food, exercise, and your body, as well as supporting your mind by changing your behaviour patterns with meaningful meditations. Visit the website to learn more: https://www.my-bmb.com/ ------------ Say HI on social: https://www.instagram.com/my_b_m_b/ https://www.tiktok.com/@my_bmb.com https://www.facebook.com/mybodymindbusiness ------------ https://youtu.be/C1p93DXEMdI #ketodiet #weightloss #MyBMB #JustinaNothard

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