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Welcome back to the CardioNerds Cardiovascular Prevention Series, where we are continuing our discussion of Glucagon-like Peptide-1 Receptor Agonists (GLP-1 RAs). This class of medications is becoming a household name, not only for their implications for weight loss but also for their effect on cardiovascular disease. CardioNerds Dr. Ty Sweeney (CardioNerds Academy Faculty Member and incoming Cardiology Fellow at Boston Medical Center), Dr. Rick Ferraro (CardioNerds Academy House Faculty and Cardiology Fellow at Johns Hopkins Hospital), and special guest Dr. Franck Azobou (Cardiology Fellow at UT Southwestern) sat down with Dr. Darren McGuire (Cardiologist at UT Southwestern and Senior Editor of Diabetes and Vascular Disease Research) to discuss important trial data on GLP-1 RAs in patients with heart disease, as well as recent professional society guidelines on their use. Show notes were drafted by Dr. Ty Sweeney. Audio editing was performed by CardioNerds Intern student Dr. Diane Masket. If you haven’t already, be sure to check out CardioNerds episode #350 where we discuss the basics and mechanism of action of GLP-1 RAs with Dr. Dennis Bruemmer. This episode was produced in collaboration with the American Society of Preventive Cardiology (ASPC) with independent medical education grant support from Novo Nordisk. See below for continuing medical education credit. Claim CME for this episode HERE. CardioNerds Prevention PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls and Quotes - GLP-1 Agonists: Diving into the Data Patients with diabetes and clinical atherosclerotic cardiovascular disease (ASCVD) or who are at high risk of ASCVD benefit from treatment with a GLP-1 RA. For persons with sufficient ASCVD risk and type 2 diabetes, GLP-1 RAs and SGLT2 inhibitors can, and often should, be used in combination. "Just like we don’t consider ‘and/or’ for the four pillars of guideline-directed medical therapy for heart failure with reduced ejection fraction, we shouldn’t parcel out these two therapeutic options...it should be both.” Setting expectations with your patients regarding injection practices, side effects, and expected benefits can go a long way toward improving the patient experience with GLP-1 RAs. Utilize a multidisciplinary approach when caring for patients on GLP-1 RAs. Build a team with your patient’s primary care provider, endocrinologist, clinical pharmacist, and nurse. “This is really a cardiologist issue. These are no longer endocrinology or primary care drugs. We need to be prescribing them ourselves just like we did back in the nineties when we took over the statin prescriptions from the endocrinology domain...we need to lead the way.” Show notes - GLP-1 Agonists: Diving into the Data For which patients are GLP-1 RAs recommended to reduce the risk of major cardiac events? For patients with type 2 diabetes and ASCVD, starting a GLP-1 RA carries a Class 1, Level of Evidence A recommendation in the most recent ESC and ACC guidelines. For patients without diabetes or clinical ASCVD with an estimated 10-year risk of CVD exceeding 10%, consideration of starting a GLP-1 RA carries a Class 2b, Level of Evidence C recommendation to reduce CV risk. The STEP-HFpEF trial showed that among patients with obesity and HFpEF, once-weekly semaglutide may be beneficial in terms of weight loss and quality of life. The results of the FIGHT and LIVE trials question the utility and safety of liraglutide in treating patients with advanced HFrEF. Of the over 17,000 patients enrolled in the SELECT trial, about 25% had heart failure, of which about one-third had HFrEF. Stay tuned for sub-analyses from that trial for more info! Can we still prescribe GLP-1 Ras in patients with well-controlled T2DM?
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Thank you for stopping by my channel :) Here are my results for my 20th week on Mounjaro and a monthly roundup on 5 mg Im absolutely thrilled with this weeks weigh in and my weight loss journey so far! Thank you all so much for your support it really does mean the world to me :) xxx You can find the Playlist for my Weekly Weigh ins here: https://youtube.com/playlist?list=PLIrmXjfhuyoCJYRmXnltUmljA3egV7503&si=1oLOTUE5wowqen2s Extra Mounjaro Videos can be found here: https://youtube.com/playlist?list=PLIrmXjfhuyoBKTTevrblxVgVEx_J4mklM&si=cZTxAs7xxD9IM0fn If you would like to follow me on instagram - mounjaro_uk_gem #mounjaro #weightloss #weightlossjourney
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Die Wechseljahre sind eine natürliche Phase im Leben einer Frau, die oft mit hormonellen Veränderungen und Gewichtszunahme einhergeht. Viele Frauen erleben in den Wechseljahren Schwierigkeiten beim Abnehmen, da ihr Stoffwechsel langsamer wird und ihr Körper mehr Fett speichert. Trotz dieser Herausforderungen ist es möglich, in den Wechseljahren Gewicht zu verlieren, wenn man die richtigen Strategien anwendet und sich konsequent an einen Plan hält. In diesem Artikel erfahren Sie, wie Sie erfolgreich 11 kg in den Wechseljahren abnehmen können.
Die Herausforderungen beim Abnehmen in den Wechseljahren
Während der Wechseljahre verändert sich der Hormonhaushalt einer Frau dramatisch, was zu einer Verlangsamung des Stoffwechsels führen kann. Dies bedeutet, dass der Körper weniger Kalorien verbrennt und es schwieriger wird, Gewicht zu verlieren. Darüber hinaus können Hitzewallungen, Schlafstörungen und Stimmungsschwankungen dazu führen, dass Frauen weniger motiviert sind, sich gesund zu ernähren und regelmäßig Sport zu treiben.
Ein weiteres Problem in den Wechseljahren ist der Verlust von Muskelmasse. Da Frauen ab einem bestimmten Alter an Muskelmasse verlieren, sinkt ihr Grundumsatz und sie verbrennen weniger Kalorien, auch in Ruhe. Dies kann dazu führen, dass Frauen in den Wechseljahren leichter an Gewicht zunehmen und schwerer abnehmen können.
Zusätzlich können emotionale und psychologische Faktoren wie Stress, Depressionen und ein geringes Selbstwertgefühl das Abnehmvorhaben in den Wechseljahren erschweren. Viele Frauen fühlen sich unattraktiv oder unwohl in ihrem Körper und greifen deshalb zu Trostessen oder ungesunden Snacks, die den Gewichtsverlust behindern.
Strategien zum erfolgreichen Abnehmen in den Wechseljahren
Um erfolgreich Gewicht in den Wechseljahren zu verlieren, ist es wichtig, eine gesunde und ausgewogene Ernährung zu sich zu nehmen. Dies bedeutet, dass Frauen auf eine ausreichende Zufuhr von Obst, Gemüse, Vollkornprodukten, magerem Eiweiß und gesunden Fetten achten sollten. Es ist auch wichtig, verarbeitete Lebensmittel, zuckerhaltige Getränke und fettreiche Snacks zu vermeiden, um die Kalorienzufuhr zu reduzieren.
Neben der Ernährung ist regelmäßige körperliche Aktivität entscheidend für den Gewichtsverlust in den Wechseljahren. Frauen sollten versuchen, mindestens 150 Minuten moderate bis intensive körperliche Aktivität pro Woche zu absolvieren, um ihren Stoffwechsel anzukurbeln und Kalorien zu verbrennen. Dies kann durch Cardio-Übungen wie Laufen, Schwimmen oder Radfahren sowie Krafttraining erreicht werden, um Muskelmasse aufzubauen und den Grundumsatz zu erhöhen.
Eine weitere wichtige Strategie beim Abnehmen in den Wechseljahren ist die Kontrolle des Stresslevels. Chronischer Stress kann zu einer erhöhten Produktion von Cortisol führen, einem Hormon, das den Appetit und die Fettansammlung fördern kann. Frauen sollten daher Stressmanagement-Techniken wie Meditation, Yoga oder Atemübungen in ihren Alltag integrieren, um ihre mentale Gesundheit zu verbessern und Gewichtszunahme zu vermeiden.
Tipps und Tricks für den Gewichtsverlust in den Wechseljahren
Um den Gewichtsverlust in den Wechseljahren zu beschleunigen, können Frauen bestimmte Tipps und Tricks anwenden. Dazu gehört zum Beispiel das Trinken von ausreichend Wasser, um den Stoffwechsel zu unterstützen und den Appetit zu kontrollieren. Frauen sollten auch darauf achten, ausreichend zu schlafen, da Schlafmangel den Stoffwechsel verlangsamen und den Gewichtsverlust behindern kann.
Es kann auch hilfreich sein, Mahlzeiten vorzubereiten und gesunde Snacks wie Obst, Gemüse oder Nüsse griffbereit zu haben, um Heißhungerattacken und ungesunde Entscheidungen zu vermeiden. Frauen sollten außerdem auf ihre Portionsgrößen achten und langsam essen, um ihr Sättigungsgefühl zu erkennen und Überernährung zu vermeiden.
Eine weitere Strategie für den erfolgreichen Gewichtsverlust in den Wechseljahren ist die Aufrechterhaltung eines stabilen Blutzuckerspiegels. Frauen sollten auf den Verzehr von raffinierten Kohlenhydraten und zuckerhaltigen Lebensmitteln verzichten und stattdessen komplexe Kohlenhydrate, Proteine und gesunde Fette zu sich nehmen, um ihren Blutzuckerspiegel zu stabilisieren und Heißhungerattacken zu vermeiden.
Zusammenfassung
Die Wechseljahre können für viele Frauen eine herausfordernde Zeit sein, insbesondere wenn es um das Abnehmen geht. Doch mit den richtigen Strategien und einem konsequenten Plan ist es möglich, auch in den Wechseljahren erfolgreich Gewicht zu verlieren. Indem Frauen auf eine gesunde Ernährung, regelmäßige Bewegung, Stressmanagement und andere Tipps und Tricks achten, können sie ihr Ziel von 11 kg Gewichtsverlust erreichen und sich in ihrem Körper wohler fühlen. Wenn Sie weitere Fragen zum Abnehmen in den Wechseljahren haben, lesen Sie unseren FAQ-Abschnitt unten oder wenden Sie sich an einen Experten für weitere Unterstützung.
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Don't miss this exclusive live event as the one and only Christina Aguilera sits down to candidly discuss her experience with the weight loss medication Ozempic. In a rare and unfiltered conversation, the iconic pop star will take us behind the scenes of her dramatic transformation, addressing the controversies and rumors that have surrounded her use of this controversial drug. #christinaaguileraozempic Prepare to be captivated as Christina opens up about the personal challenges that led her to explore Ozempic, the ups and downs of her journey, and the impact it has had on her physical and mental well-being. She'll dive deep into the ethical discussions surrounding celebrity access to these types of treatments, offering a unique perspective that challenges the status quo. This live event is your chance to hear Christina's story straight from the source. Ask your burning questions, gain insights into the realities of Ozempic use, and join the conversation as we explore the broader implications of this medical and societal phenomenon. Tune in live to witness an unforgettable and thought-provoking discussion that promises to leave a lasting impression. Christina Aguilera's Ozempic experience will be revealed like never before - you won't want to miss it!" Christina Aguilera Opens Up About Her Ozempic Experience - Christina Aguilera Ozempic Christina Aguilera Opens Up About Her Ozempic Experience - Christina Aguilera Ozempic Christina Aguilera Opens Up About Her Ozempic Experience - Christina Aguilera Ozempic
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Keto Clean’s journey on Shark Tank was nothing short of transformational. The innovative keto-friendly product caught the attention of the sharks and captivated viewers across the nation. From pitching their product to negotiating with the sharks, Keto Clean’s founders faced challenges and triumphs that ultimately led to their success on the show. In this article, we will delve into the details of Keto Clean’s time on Shark Tank and explore how they emerged victorious in the competitive world of entrepreneurship.
The Pitch
When Keto Clean’s founders stepped onto the Shark Tank stage, they were prepared to showcase their unique product and convince the sharks of its value. With a captivating presentation and a compelling story behind the brand, Keto Clean managed to capture the attention of all five sharks. The founders eloquently explained the benefits of their keto-friendly product and highlighted its potential in the market. Their passion and dedication to their business resonated with the sharks, setting the stage for a successful pitch.
As the sharks grilled the founders with tough questions and raised concerns about the product’s scalability, Keto Clean remained composed and confident in their responses. They addressed each question with poise and transparency, demonstrating their deep understanding of the industry and their commitment to the success of their brand. The sharks were impressed by Keto Clean’s knowledge and expertise, which ultimately played a crucial role in sealing the deal.
Despite facing intense scrutiny and pressure from the sharks, Keto Clean’s founders stood their ground and defended their business model with conviction. They remained true to their values and vision for the brand, refusing to compromise on their principles in exchange for a deal. This unwavering dedication to their mission left a lasting impression on the sharks and set Keto Clean apart from the competition.
The Negotiation
As the negotiations heated up and the sharks began making offers, Keto Clean’s founders carefully weighed their options and considered each proposal with meticulous attention to detail. They remained focused on securing a deal that would not only benefit their business but also align with their long-term goals and values. The founders engaged in strategic back-and-forth discussions with the sharks, leveraging their knowledge of the industry and their understanding of market trends to drive a favorable outcome.
After carefully evaluating the offers on the table, Keto Clean’s founders ultimately accepted a deal from one of the sharks that aligned with their vision for the brand. The terms of the agreement were mutually beneficial for both parties, setting the stage for a successful partnership that would propel Keto Clean to new heights. The negotiation process was a testament to the founders’ resilience and determination, showcasing their ability to navigate challenges and seize opportunities in the competitive world of entrepreneurship.
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Following their appearance on Shark Tank, Keto Clean experienced a surge in demand for their product and a significant increase in brand awareness. The exposure from the show catapulted Keto Clean into the spotlight, garnering attention from consumers and retailers alike. The founders wasted no time capitalizing on their newfound success, leveraging their appearance on Shark Tank to expand their distribution network and reach new markets.
With the support of their shark investor, Keto Clean was able to scale their business and introduce new product lines to meet the growing demand for keto-friendly options. The founders remained steadfast in their commitment to quality and innovation, continuously refining their products to meet the evolving needs of their customers. As Keto Clean continued to thrive in the competitive health and wellness industry, their journey on Shark Tank served as a catalyst for their growth and success.
Overall, Keto Clean’s transformational journey on Shark Tank is a testament to the power of perseverance, passion, and strategic thinking in the world of entrepreneurship. By showcasing their ingenuity and resilience on a national stage, Keto Clean’s founders not only secured a deal with a shark investor but also paved the way for a bright future ahead. Their journey serves as an inspiration to aspiring entrepreneurs and a reminder that with dedication and determination, anything is possible.
Summary and FAQ
As Keto Clean continues to thrive in the competitive market, it’s essential to understand the key takeaways from their journey on Shark Tank. Here are some frequently asked questions and a summary of Keto Clean’s transformational experience on the show:
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The ketogenic diet has gained immense popularity in recent years for its numerous health benefits, including weight loss, improved mental clarity, and increased energy levels. However, finding keto-friendly snacks that satisfy your sweet tooth can be challenging. That’s where Kiss My Keto Gummies come in – delicious, low-carb treats that make staying on track with your keto lifestyle a breeze.
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Kiss My Keto Gummies are the perfect solution for anyone following a ketogenic diet who craves a sweet treat without the guilt. These gummies are made with high-quality ingredients that are low in carbs and sugar, making them a great option for satisfying your cravings while staying in ketosis. Plus, they come in convenient single-serve packs that are perfect for on-the-go snacking.
Each serving of Kiss My Keto Gummies contains only 3g of net carbs, making them a guilt-free indulgence that won’t derail your ketosis. They are sweetened with erythritol and stevia, two natural sweeteners that won’t spike your blood sugar levels. Whether you’re looking for a mid-afternoon snack or a late-night treat, these gummies are sure to hit the spot.
Not only are Kiss My Keto Gummies delicious, but they are also free from artificial flavors, colors, and preservatives. You can feel good about indulging in these tasty treats knowing that they are made with real, wholesome ingredients. Plus, they are gluten-free and dairy-free, making them suitable for a wide range of dietary preferences.
Benefits of Kiss My Keto Gummies
One of the biggest benefits of Kiss My Keto Gummies is their convenience. You can easily toss a pack in your bag or desk drawer for a quick and satisfying snack whenever hunger strikes. They are also portion-controlled, so you don’t have to worry about overindulging and derailing your progress on the keto diet.
In addition to being a convenient snack option, Kiss My Keto Gummies are also a great way to satisfy your sweet cravings without sacrificing your health goals. They are made with high-quality ingredients that are proven to support a ketogenic lifestyle, helping you stay on track and reach your weight loss goals faster.
Another benefit of Kiss My Keto Gummies is their versatility. You can enjoy them on their own as a standalone snack, or get creative and incorporate them into your favorite keto-friendly recipes. Whether you’re craving something sweet or looking for a way to enhance the flavor of your favorite dishes, these gummies are sure to deliver.
Customer Reviews and Testimonials
Customers who have tried Kiss My Keto Gummies rave about their delicious taste and convenience. Many have praised the gummies for being a satisfying snack that helps them stay on track with their keto diet. Some have even shared creative ways to enjoy the gummies, such as adding them to smoothie bowls or using them as a topping for keto-friendly desserts.
One customer said, “I love having Kiss My Keto Gummies on hand for when I need a sweet pick-me-up. They satisfy my cravings without kicking me out of ketosis, and the portion-controlled packs make it easy to enjoy them guilt-free.” Another customer shared, “I was skeptical at first, but these gummies are seriously good. They have become my go-to snack when I need something sweet but don’t want to sabotage my progress.”
If you’re looking for a tasty, keto-friendly snack that won’t derail your progress, give Kiss My Keto Gummies a try. With their delicious taste, convenience, and high-quality ingredients, these gummies are sure to become a staple in your keto snack arsenal.
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Are Kiss My Keto Gummies suitable for vegetarians?Yes, Kiss My Keto Gummies are made with vegetarian-friendly ingredients and do not contain any animal-derived products.
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How many gummies come in a pack?Each pack of Kiss My Keto Gummies contains 12 individual serving packets, perfect for portion-controlled snacking.

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Obesity is a major public health issue affecting millions of individuals around the world. It is a complex condition with various contributing factors, including genetics, lifestyle, and environmental influences. For some individuals struggling to lose weight through diet and exercise alone, prescription medications may be a viable option. One such medication that has gained popularity in recent years for weight loss is semaglutide.
What is Semaglutide?
Semaglutide is a medication originally developed for the treatment of type 2 diabetes. It belongs to a class of drugs called glucagon-like peptide-1 receptor agonists, which work by mimicking the effects of a hormone called GLP-1 that helps regulate blood sugar levels. In addition to its effects on blood sugar control, semaglutide has been shown to promote weight loss in individuals with obesity.
Studies have shown that semaglutide can lead to significant weight loss when used in combination with lifestyle modifications such as diet and exercise. In a clinical trial known as the STEP program, participants who took semaglutide lost more weight compared to those who received a placebo. This has sparked interest in using semaglutide for weight loss in individuals who are struggling to achieve their weight loss goals through traditional means.
How Does Semaglutide Work for Weight Loss?
The exact mechanism by which semaglutide promotes weight loss is not fully understood, but researchers believe it involves several key factors. One of the primary ways semaglutide helps with weight loss is by reducing appetite and food intake. This is thought to occur through its effects on the brain’s appetite-regulating centers, leading to feelings of fullness and reduced cravings for food.
In addition to its effects on appetite, semaglutide may also help with weight loss by slowing down the emptying of the stomach, which can lead to prolonged feelings of fullness after meals. This can help individuals consume fewer calories overall, leading to weight loss over time. Semaglutide may also have metabolic effects that help improve insulin sensitivity and fat metabolism, leading to more efficient energy utilization and fat loss.
Is Semaglutide Safe for Weight Loss?
Like any medication, semaglutide can have potential side effects and risks that should be considered before starting treatment. Common side effects of semaglutide include nausea, vomiting, diarrhea, and constipation, which may improve over time as the body adjusts to the medication. More serious side effects can occur, such as pancreatitis or gallbladder problems, so it is important to discuss the potential risks and benefits with a healthcare provider.
Individuals with a history of pancreatitis, thyroid cancer, or multiple endocrine neoplasia syndrome type 2 should not take semaglutide. It is also not recommended for use in individuals with a history of severe gastrointestinal disease or a personal or family history of medullary thyroid cancer. Pregnant or breastfeeding women should not use semaglutide for weight loss.
How Can I Get Semaglutide for Weight Loss?
Before starting semaglutide for weight loss, it is important to consult with a healthcare provider to determine if it is the right option for you. Semaglutide is typically prescribed for weight loss in a higher dose than what is used for diabetes treatment, so it is essential to follow your healthcare provider’s guidance on dosing and monitoring. Semaglutide is available by prescription only and may not be covered by all insurance plans, so it is important to check with your insurance provider about coverage options.
For individuals who are struggling to lose weight through traditional methods and are interested in exploring the use of semaglutide for weight loss, talking to a healthcare provider is the first step. Your healthcare provider can evaluate your individual health status and weight loss goals to determine if semaglutide is a suitable option for you. With proper guidance and monitoring, semaglutide may be a helpful tool in achieving and maintaining weight loss for individuals with obesity.
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▶ Watch Next: The 4 Labs Every Man Over 30 Needs https://youtu.be/jrwZo9SaDiA?si=B29PepHihhLrF_jj --- Losing weight as a busy man isn’t about doing more—it’s about doing the right things first thing in the morning. In this video, I break down the 5 simple morning habits that helped me burn fat, boost energy, and stay consistent without crash diets or 2-hour workouts. These habits are especially powerful for men over 30 who need a smarter way to stay lean, focused, and in control of their health. And if your fat loss has stalled or energy still feels off, you need labs. Watch the next video to see the 4 tests I recommend for every man over 30. --- What You’ll Learn: The 5 morning habits that helped me lose fat Why your metabolism is slower in the morning—and how to wake it up The role of water, movement, and light in fat loss How to build a repeatable routine that fits your life When to check your hormones and energy levels through lab testing --- SEO Keywords: morning weight loss routine, how to lose fat fast men, fat-burning morning habits, men’s morning routine for weight loss, lose belly fat over 30, hormone tests for men, labs for weight loss, men’s health fat loss tips --- DISCLAIMER: This video is purely educational and does not constitute medical advice. The content of this video is my personal opinion and not that of my employer(s). Use of this information is at your own risk. Chris Caldwell, MSN-FNP will not assume any liability for any direct or indirect losses or damages that may result from the use of the information contained in this video including but not limited to economic loss, injury, illness, or death.
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